Pulmonary Illness and E-Cigarettes: New Devices with New Diseases

We are seeing patients with similar clinical characteristics that shared the used of e-cigarettes. Even though we have been unable to identify one single responsible component or a set of them, clearly the use of e-cigarettes has brought new pathologies.

Enfermedad pulmonar y cigarrillos electrónicos: Nuevos dispositivos con nuevas enfermedades

E-cigarettes are electronic battery powered devices that heat a liquid forming an inhalable aerosol. Several pulmonary diseases related to e-cigarettes have been reported as isolated cases, but never a series with a significant number of patients.

This study defined cases as people reporting the use of e-cigarettes 90 days prior symptom onset presenting pulmonary infiltration on imaging not attributed to other conditions.


Read also: E-Cigarettes vs. Nicotine Therapy to Stop Smoking.


53 were registered, mostly men, mean age 19. Mostly presented with respiratory symptoms (98%), gastrointestinal symptoms (81%) and constitutional symptoms (100%). They all presented bilateral pulmonary infiltrates.

94% of patients required hospitalization and one third mechanical ventilation. One patient died in hospital.

84% of patients reported having used tetrahydrocannabinol products in their devices, though there is a wide range of products and devices in the market.



Read also: E-Cigarettes: No Definitive Evidence on Their Potential Cardiovascular Effect, but Some Suggest Caution


Surveillance in one US state showed visits for severe pulmonary illness doubled between 2018 and 2019.

Conclusions

All patients used e-cigarettes and presented similar clinical characteristics, symptoms and imaging, not attributable to other conditions. Further study is required to characterize their physiopathology and identify the definitive cause.

Original Title: Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin — Preliminary Report.

Reference: Jennifer E. Layden et al. N Engl J Med. 2019 Sep 6. [Epub ahead of print].


Subscribe to our weekly newsletter

Get the latest scientific articles on interventional cardiology

We are interested in your opinion. Please, leave your comments, thoughts, questions, etc., below. They will be most welcome.

More articles by this author

STEACS and the Use of Bivalirudin vs. Heparin: In Search of BRIGHT-4 Outcomes

Various studies and registries have previously shown the impact of post-percutaneous coronary intervention (PCI) complications on the survival of patients with ST-segment elevation acute...

TAVR and Atrial Fibrillation: What Anticoagulants Should We Use?

The prevalence of atrial fibrillation (AF) in TAVR patients ranges from 15 to 30%, depending on series. This arrhythmia has been associated to higher...

Ultrathin vs Thin-Strut Stents in PCI Patients at High Bleeding Risk

Several in vivo studies have shown that ultrathin stents present lower thrombogenic risk vs. thin-strut stents, which reflects in lower rates of target lesion...

Should We Withdraw Anticoagulation Before TAVR?

Approximately one-third of patients undergoing transcatheter aortic valve replacement (TAVR) have atrial fibrillation and are on oral anticoagulant (OAC) therapy. This creates a complex...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

TCT 2024 | FAVOR III EUROPA

The study FAVOR III EUROPA, a randomized trial, included 2,000 patients with chronic coronary syndrome, or stabilized acute coronary syndrome, and intermediate lesions. 1,008...

TCT 2024 | TRISCEND II

This randomized study included 400 patients; 267 were treated with EVOQUE valve and 133 with optimal medical treatment (OMT). After one-year follow-up, there were no...

TCT 2024 – ACCESS-TAVI: Comparing Percutaneous Access Closure Strategies After TAVI

Vascular access complications following transcatheter aortic valve implantation (TAVI) remain common. However, few studies compare vascular access closure methods.  Based on the CHOICE-CLOSURE and MASH...