ESC 2014.

ODYSSEY LONG TERM: Safety and efficacy of long-term alirocumab

This was a prospective, randomized, controlled study comparing monoclonal antibody alirocumab with placebo in patients with hypercholesterolemia...

COPPS-2: Colchicine for prevention of post-pericardiotomy syndrome and postoperative atrial fibrillation

180 patients with colchicine 0.5 mg twice daily from 48-72 hs. before surgery versus 180 patients to...

PARADIGM-HF: New family of drugs for chronic heart failure

Therapy in heart failure has been to focus the neurohormonal pathways such as the renin-angiotensin-aldosterone system. Natriuretic...

CONFIRM HF: Is it safe to replace intravenous iron in patients with chronic heart failure

This study aimed to assess whether iron replacement versus placebo could improve physical activity in patients with...

NECTAR HF: Chronic vagal stimulation for heart failure with low ejection fraction

The increased sympathetic activity and reduced parasympathetic tone are important pathophysiological contributors to the progression of heart...

POPE-2: Colchicine to prevent pericardial effusion after cardiac surgery

The incidence of asymptomatic pericardial effusion after cardiac surgery is high. The aim of this study was...

MORE-CRT: Cardiac resynchronization with quadrupole electrode reduces complications

In approximately 10% of patients for resynchronization therapy implantation of ventricular lead is not possible for anatomical...

SOLID-TIMI 52: Darapladib to reduce new cardiovascular events after myocardial infarction

This study randomized 1: 1 patient who had been hospitalized for acute coronary syndrome within 30 days...