Reference: Planer et al. International Journal of Cardiology 2012 (in press) Prognosis of patients enrolled in acute myocardial infarction with ST segment elevation (STEMI) has improved markedly, particularly as a result of reperfusion therapy. Despite these improvements, patients with diabetes mellitus (DM) are a high risk group in the short and long term compared with…
Six Months Sufficient for Dual Antiplatelet Therapy
Reference: Kandzari DE, Barrer CS, Leon MB, et al. Dual antiplatelet therapy duration and clinical outcomes following treatment with zotarolimus-eluting stents. JACC Cardiovasc Interv 2011; 4: 1119-28.2011; 4: 1119-28. Patients treated with zotarolimus-eluting stents (ZES) suffer no excess late ischemic events if they take dual antiplatelet therapy for 6 months instead of 12 months or longer,…
Incomplete Revascularization Linked With Mortality in Multivessel Disease Patients
Reference: Wu C, Dyer AM, Kinas SB, et al. Impact of incomplete revascularization on long-term mortality after coronary stenting. Circ Cardiovasc Interv 2011; 4: 413-21. Complete revascularization was defined as a reduction of stenosis to less than 50% in all diseased (≥ 70% stenosis) lesions in major epicardial coronary vessels at the initial hospitalization or within…
Off-Pump CABG Reduces Postoperative Stroke vs. Standard Surgery
Reference: Afilalo J, RAsti M, Ohayon SM, et al. Off-pump vs on-pump coronary artery bypass surgery: an updated meta-analysis and meta-reggresion of randomized trials. Eur Heart J 2011. Epub ahead of print. Patients who undergo off-pump coronary artery bypass grafting (CABG) surgery experience nearly one-third fewer postoperative strokes than those who receive standard surgery using cardiopulmonary…
System Delays for STEMI patients linked to subsequent heart failure care
Reference: Terkelsen CJ, Jensen LO, Tilsted H-H, et al. Health care system delay and heart failure in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: Follow-up of population-based medical registry data. Ann Intern Med 2011; 155: 361-7. In patients with ST-segment myocardial infarction (STEMI), delays in obtaining primary percutaneous coronary intervention (PCI)…
Coronary CTA Use in Emergency Department saves time and money
Reference: Goldstein JA, Chinnaiyan KM, Abidov A, et al. The CT-STAT (coronary computed tomographic angiography for systemic triage of acute chest pain patients to treatment) trial. J Am Coll Cardiol 2011; 58: 1414-22. Using coronary computed tomographic angiography (CTA) as a screening tool for low-risk patients with chest pain in the emergency department achieves lower costs…
Ticagrelor vs. Clopidogrel in ST elevation MI: Pros and cons
Platelet Inhibition in the PLATO study: insights from the ECG substudy. En el Estudio PLATO quedó evidenciado que el Ticagrelor disminuyó la mortalidad a 12 meses en comparación con el Clopidogrel en el tratamiento de pacientes post-angioplastía por un síndrome coronario agudo o por un cuadro estable (4,5 vs. 5,9%; P<0.001). Estos resultados fueron del…
Tres Reglas para Identificar Infarto en la Guardia
Prioridad en la Evaluación Electrocardiográfica Inmediata en la Guardia: Validación de un Algoritmo En las actuales directrices internacionales se recomienda la inmediata realización ( Con el objeto de identificar los escenarios clínicos asociados a la presentación de un paciente con IAMST, un estudio epidemiológico recientemente publicado analizó todos los casos registrados durante el período 2007…