This was a prospective, randomized, controlled study comparing monoclonal antibody alirocumab with placebo in patients with hypercholesterolemia and high cardiovascular risk. At 24 weeks follow-up LDL cholesterol reduction with alirocumab was 61% versus 0.8% placebo (p <0.0001). This reduction was maintained at 52 weeks.
Jennifer Robinson
2014-08-31
Original title: Long-term safety, tolerability and efficacy of alirocumab versus placebo in high cardiovascular risk patients: first results from the ODYSSEY LONG TERM study in 2,341 patients.
