Delays in the treatment of symptomatic aortic stenosis (AS) reduce prognosis, especially in elderly patients. Accurate assessment of AS severity is crucial to avoid overtreatment and its associated risks. A transthoracic echocardiogram (TTE) is the initial evaluation in the diagnostic algorithm, and severity values are well established. However, some patients may obtain discordant data due<a href="https://solaci.org/en/2024/06/07/low-flow-aortic-stenosis-what-is-the-value-of-valve-calcification-in-its-interpretation/" title="Read more" >...</a>
Is Intravascular Lithotripsy Equally Effective in All Coronary Calcification Patterns?
Coronary calcifications pose a complex challenge with a high incidence (25% of all angioplasties), thus implying difficult management and adverse long-term outcomes, such as an increased risk of events, especially the need for repeat revascularization. The main mechanisms of long-term failure include stent underexpansion and, in particular, minimal post-deployment stent area. Intravascular lithotripsy (IVL) has<a href="https://solaci.org/en/2024/05/28/is-intravascular-lithotripsy-equally-effective-in-all-coronary-calcification-patterns/" title="Read more" >...</a>
Coronary Calcification: More Frequent Use of Coronary Lithotripsy as a Recommendation
Coronary calcification, whether concentric or eccentric, has always posed a challenge in percutaneous coronary intervention (PCI) due to difficulties in plaque preparation, device navigability, proper stent apposition, drug release, and potential complications during the procedure. This study analyzed 262 patients who participated in the four Disrupt CAD OCT Studies and underwent PCI using coronary lithotripsy followed<a href="https://solaci.org/en/2023/11/02/coronary-calcification-more-frequent-use-of-coronary-lithotripsy-as-a-recommendation/" title="Read more" >...</a>
Drug Coated Balloons: Link between Femoropopliteal Lesion Calcification Grade and Clinical Outcomes
At present, the use of drug coated balloons (DCB) in femoropopliteal territory is more and more frequent. However, when it comes to treating moderate to severe calcification, the evidence is still limited. Using a peripheral artery calcification scoring system (PACSS) has been associated to clinical outcomes after DCB angioplasty for femoropopliteal lesions. The system categorizes<a href="https://solaci.org/en/2023/05/11/drug-coated-balloons-link-between-femoropopliteal-lesion-calcification-grade-and-clinical-outcomes/" title="Read more" >...</a>
Outflow Tract Calcification and the Best Valve in This Context
Moderate or severe left ventricle outflow tract calcification increases the risk of annulus rupture, residual aortic regurgitation and the need for a second valve. This recent study analyzed the performance of different contemporary prosthetic valves in patients with this particular anatomy. Since the early days of transcatheter aortic valve replacement (TAVR) outflow tract calcification has<a href="https://solaci.org/en/2020/09/10/outflow-tract-calcification-and-the-best-valve-in-this-context/" title="Read more" >...</a>
TAVR: Reasons to Consider Mitral Annular Calcification
Courtesy of Dr. Carlos Fava. Aortic valve calcification and mitral annular calcification have the same etiology and are frequently present in high-risk patients undergoing transcatheter aortic valve replacement (TAVR). The implications of mitral annular calcification for patients undergoing TAVR has not been entirely clarified yet. The study examined 782 patients with severe aortic stenosis who underwent<a href="https://solaci.org/en/2017/02/14/tavr-reasons-to-consider-mitral-annular-calcification/" title="Read more" >...</a>
Extreme Valve Calcification in TAVI might compromise technical success
Original Title: Ballon-Expandable Trancatheter Aortic valve Replacement in Patients whit Extreme Aortic Valve Calcification. Reference: Yigal Abramowitz, et al. Catetherization and Cardiovascular Intervention 2016;87:117-1179. Courtesy of Dr. Carlos Fava. Transcatheter aortic valve replacement (TAVI) emerged as a valid option to treat high risk inoperable patients. A group of these patients presents extreme valve<a href="https://solaci.org/en/2016/06/16/extreme-valve-calcification-in-tavi-might-compromise-technical-success/" title="Read more" >...</a>
Severe coronary calcification is a predictor of coronary events in acute coronary syndromes
Original title: Ischemic Outcomes After Coronary Intervention of Calcified Vessels in Acute Coronary Syndromes. Pooled Analysis From the HORIZONS and ACUITY Trials. Reference: Philippe Généreux, et al. J Am Coll Cardiol 2014;63:1845-54 Calcification of the arteries has always been a challenge and a generator of problems during coronary angioplasty, but its impact on acute coronary syndromes has not<a href="https://solaci.org/en/2014/05/21/severe-coronary-calcification-is-a-predictor-of-coronary-events-in-acute-coronary-syndromes/" title="Read more" >...</a>
Myocardial Damage in MAC
Mitral annulus calcification (MAC) affects between 8% and 23% of the population. It is more common in women and patients with renal insufficiency. This phenomenon is characterized by an increase in valvular annulus fibrosis, which can extend and affect the leaflets. The presence of MAC is associated with valve regurgitation or stenosis, increasing mortality and<a href="https://solaci.org/en/2024/07/18/myocardial-damage-in-mac/" title="Read more" >...</a>
ULTIMATE III: Use of IVUS for Coronary De Novo Lesion Drug Coated Balloon Angioplasty
Percutaneous coronary intervention (PCI) with drug eluting stents (DES) can present limitations, especially in the form of stent thrombosis or instent restenosis (ISR). These findings have furthered the development of drub coated balloons (DCB). The safety and efficacy of DCB have already been shown in the context of ISR and de novo small vessel coronary<a href="https://solaci.org/en/2024/07/12/ultimate-iii-use-of-ivus-for-coronary-de-novo-lesion-drug-coated-balloon-angioplasty/" title="Read more" >...</a>