DeFACTO: Diagnostic Precision of CT Angiography in Determining FFR. Read article James K. Min2012-08-25
FAME 2: Cost-effectiveness of FFR-guided angioplasty in patients with stable angina
Introduction: FAME study 2, presented at the European Congress of Cardiology 2012, is a multicenter study that randomized patients with stable angina FFR-guided angioplasty and optimal medical therapy versus optimal medical therapy alone. The study was stopped early due to a significantly higher rate of primary endpoints, (death, MI, or urgent revascularization), in the conservative<a href="https://solaci.org/en/2015/06/24/fame-2-cost-effectiveness-of-ffr-guided-angioplasty-in-patients-with-stable-angina/" title="Read more" >...</a>
RIPCORD study: FFR changes clinical consideration of chest pain
The objective of this study was to evaluate whether routine use of FFR in all the coronary arteries could change the strategy in stable patients that underwent angiography for the investigation of a chest pain. We included 200 patients with chest pain; for 72 of them, the strategy would be to provide medical treatment by<a href="https://solaci.org/en/2015/06/24/ripcord-study-ffr-changes-clinical-consideration-of-chest-pain/" title="Read more" >...</a>
SYNTAX II: multiple vessels using iFR / FFR and IVUS
This study is still in progress and includes patients using SYNTAX II score based on functional invasive evaluation with iFR / FFR and performing angioplasty guided by IVUS using the biodegradable polymer everolimus eluting stent. The study seeks to prove superiority versus the first generation paclitaxel-eluting stent and non-inferiority versus surgery using historical data. We<a href="https://solaci.org/en/2015/06/24/syntax-ii-multiple-vessels-using-ifr-ffr-and-ivus/" title="Read more" >...</a>
HeartFlowNXT: Using noninvasive FFR shows promising results
The use of fractional flow reserve (FFR) is useful to determine the significance of coronary lesions. The ability to perform this physiologicalevaluation in a noninvasive base is an interesting alternative.The primary objective of the study was to compare the noninvasive FFRusing multislice CT versus invasive FFR. 357 patients were included in this multicenter study succeeded<a href="https://solaci.org/en/2015/06/24/heartflownxt-using-noninvasive-ffr-shows-promising-results/" title="Read more" >...</a>
ADVISE II: iFFR comparable toFFRbut with out adenosine
Several studies tested the utility of fractional flow reserve (FFR) to assess coronary lesions functionally. The FFR required for its measurement amaximum hyperemia that usually, is achieved with adenosine infusion. The “InstantaneousWave-freeRatio™” or iFR, has the advantage of not requiring maximum hyperemia.This prospective, multicenter, observational study that included 690 patients detectedthat iFR adequately classified 91.6%<a href="https://solaci.org/en/2015/06/24/advise-ii-iffr-comparable-toffrbut-with-out-adenosine/" title="Read more" >...</a>
IVUS or FFR Guided in MV Disease and ACS?
Costantino R. Costantini 2012-08-09
FFR to guide treatment of secondary vessel on bifurcations
Original title: Randomized Comparison of FFR-Guided and Angiography-Guided Provisional Stenting of True Coronary Bifurcation Lesions The DKCRUSH-VI (Double Kissing Crush Versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions VI) Trial. Reference: Shao-Liang Chen et al. J Am Coll Cardiol Intv. 2015. Online before print. Angiography for guiding the need to implant a stent in the side<a href="https://solaci.org/en/2015/04/22/ffr-to-guide-treatment-of-secondary-vessel-on-bifurcations/" title="Read more" >...</a>
Peripheral adenosine infusion versus central access infusion during measurement of FFR
Original title: FFR in the Transradial Era: Will Hand Vein Adenosine Infusion Suffice?A Comparative Study of the Extent, Rapidity, and Stability of Hyperemia From Hand and Femoral Venous Routes of Adenosine Administration. Reference: Peter Scott et al. J Am Coll Cardiol Intv. 2015, online before print. The aim of this study was to compare the administration of<a href="https://solaci.org/en/2015/04/15/peripheral-adenosine-infusion-versus-central-access-infusion-during-measurement-of-ffr/" title="Read more" >...</a>
Linear relationship between prognosis and FFR value
Original title: Prognostic Value of Fractional Flow Reserve Linking Physiologic Severity to Clinical Outcomes. Reference: Nils P. Johnson et al. J Am Coll Cardiol 2014;64:1641–54. Fractional flow reserve (FFR) has become an essential tool for guiding treatment, but its graded relationship to prognosis and its influence by medical treatment vs revascularization, remains unclear. The hypothesis of this study<a href="https://solaci.org/en/2015/02/13/linear-relationship-between-prognosis-and-ffr-value/" title="Read more" >...</a>