The REVIVED-BCI2 included 700 patients with ejection fraction ≤35% with extended coronary artery disease and plausible PCI. Patients were randomized to PCI plus optimal and complete medical treatment (OMT) according to the current guidelines. 347 patients received PCI and 353 OMT. Primary end point was all cause death and hospitalization for cardiac failure. There were<a href="https://solaci.org/en/2022/08/31/esc-2022-revived-bcis2-3/" title="Read more" >...</a>
Non-adherence to medication in patients with acute coronary syndrome (ACS) remains to be solved; the use of polypills and a closer follow up have been tried out (follow up calls and motivation groups). Antiaggregation guidelines recommend dual antiplatelet therapy (DAPT) for at least one year after ACS. Adherence to drug treatment is comprised of multiple<a href="https://solaci.org/en/2022/08/30/adherence-to-p2y12-inhibitors-in-acute-coronary-syndrome-prognosis/" title="Read more" >...</a>
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease are associated to hospitalization and mortality. When associated to severe mitral regurgitation, not only do these two conditions have poor evolution, but they also limit the possibility of surgical valve replacement, given its high risk. Edge-to-edge repair with MitraClip has been shown beneficial in a group of<a href="https://solaci.org/en/2022/08/17/mitraclip-in-patients-with-copd-a-valid-option/" title="Read more" >...</a>
Severe tricuspid regurgitation (TR) is associated with high mortality and morbidity. For patients with high surgical risk that cannot get surgery, the endovascular option has become an attractive solution this past decade. Transcatheter intervention has focused on edge-to-edge repair and valve replacement. However, their success depends on anatomical characteristics and imaging guidance effectiveness. The bicaval<a href="https://solaci.org/en/2022/07/15/tricvalve-in-patients-with-severe-tricuspid-regurgitation-promising-results-at-6-months/" title="Read more" >...</a>
Takotsubo Syndrome (STT) is characterized by acute cardiac failure which can be reversed in many occasions, but is associated with morbidity and mortality at short and long term. It is most frequent among women, especially after menopause. However, gender differences have not been looked into when analyzing the evolution of this cardiomyopathy. This was an<a href="https://solaci.org/en/2022/06/22/takotsubo-syndrome-does-gender-impact-prognosis/" title="Read more" >...</a>
In general, thrombus aspiration in acute myocardial infarction (AMI) has not been shown beneficial by large studies. It could even be prejudicial, since it has been associated with stroke. However, there are certain scenarios where the presence of a significant number of these prevents us from reaching adequate TIMI flow 3, or is associated with<a href="https://solaci.org/en/2022/06/15/the-current-role-of-thrombus-aspiration-in-primary-pci/" title="Read more" >...</a>
According to the European Society of Cardiology (ESC Guidelines 2021) an early invasive strategy is recommended (<24h) for high-risk patients with acute coronary syndrome with no ST elevation (NSTE-ACS), namely patients presenting a rise or fall in cardiac troponin, dynamic ST- or T-wave changes and GRACE risk score >140. Early intervention (<2h) is reserved for<a href="https://solaci.org/en/2022/06/09/when-is-the-ideal-timing-for-nste-acs-percutaneous-intervention/" title="Read more" >...</a>
Severe mitral regurgitation is associated to cardiac failure and hospitalization and over time is accompanied by kidney failure, which leads to higher mortality. In the COAPT study, in patients with low ejection fraction, MitraClip showed benefits over medical treatment, but there was an important group of people with kidney function deterioration. The evolution and benefit<a href="https://solaci.org/en/2022/06/01/mitraclip-reduces-renal-function-deterioration/" title="Read more" >...</a>
According to the STITCH and STITCHES trials, in patients with coronary artery disease and deteriorated left ventricular ejection fraction (EF), revascularization of a viable heart might reverse left ventricular systolic dysfunction. In these patients, improved EF after coronary revascularization appears to increase long term survival, particularly after cardiac artery bypass grafting (CABG), compared against medical<a href="https://solaci.org/en/2022/05/16/improved-ventricular-function-post-revascularization-fewer-events-across-subgroups/" title="Read more" >...</a>
Mitral valve prolapse is the most frequent cause of mitral valve regurgitation and is associated to hospitalization for cardiac failure and mortality. At present, the preferred treatment for operable patients is mitral valve surgical repair. Transcatheter edge to edge repair (TEER) has shown great benefit patients at high surgical risk; however, it has not been<a href="https://solaci.org/en/2022/05/12/transcatheter-edge-to-edge-repair-is-favorable-for-elderly-patients-at-high-surgical-risk/" title="Read more" >...</a>