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Full conversion from transfemoral to transradial: similar success rate and far less complications.

Original title: Full conversion from transfemoral to transradial approach for percutaneous coronary interventions results in a similar success rate and a rapid reduction of in-hospital cardiac and vascular major events. Reference: Vincent Dangoisse et al. EuroIntervention 2013;9:345-352.   Although the transfemoral approach has clear disadvantages when it comes to bleeding complications, it continues to be the preferred approach...

Transradial access plus bivalirudin, the best combination to reduce bleeding

Original title: Comparison of bivalirudin and radial access across a spectrum of preprocedural risk of bleeding in percutaneous coronary intervention: Analysis from the National Cardiovascular Data Registry. Reference: Baklanov DV et al. Circ Cardiovasc Interv. 2013, article in press. Bleeding complications are clearly associated to mortality increase and two of the current best strategies to reduce bleeding are...

Implanting a second valve and embolization are two complications that increase mortality

Original title: Determinats and Outcomes of Acute transcatheter Valve-in Valve Therapy or Embolization. Reference: Raj R Makkar, et al. J Am Coll Cardiol 2013;62:418-30   Percutaneous aortic valve implantation has proven to be feasible, safe and a successful follow up. Only in a few patients is the two-valve implantation necessary due to bad positioning or embolism but...

Ticagrelor similar to clopidogrel in terms of coronary flow and myocardial perfusion

Título original: Angiographic Outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes). Referencia: Vijay Kunadian et al. J Am Coll Cardiol Intv 2013;6:671–83. In the PLATO (Platelet Inhibition and Patient Outcomes) trial, treatment with ticagrelor compared with clopidogrel resulted in a significant reduction in the combined endpoint of cardiac death, heart attack or stroke in patients undergoing...

Percutaneous Left Atrial Appendage Suture: more options in atrial fibrillation patients with antiguagulation contraindication

Original title: Percutaneous Left Atrial Appendage Suture Ligation Using the Lariat Device In Patines UIT Atrial Fibrillation Reference: Krystof Bartus, et al. J Am Coll Cardiol 2013;62:108–18. Atrial fibrillation (AF) is the most frequent arrhythmia and is associated with a 5 fold increase in stroke risk and the resulting morbimortality. Warfarin anticoagulation therapy can be effective but only...

Thoracoscopic Stand-Alone Left Atrial Appendectomy

Original title: Thoracoscopic Stand-Alone Left Atrial Appendectomy for Thromboembolism Prevention in Nonvalvular Atrial Fibrilation. Reference: Toshiya Ohtsuka, et al. J Am Coll Cardiol 201362;2:103-107 Anticoagulation is commonly prescribed as prevention therapy against AF-induced thromboembolism. However, even a correct prescription may result in an unexpected stroke due to cardioembolic stroke. Different left atrial appendectomy techniques and devices are currently...

Percutaneous Left Atrial Appendage Closure With the AMPLATZER : a valid alternative when anticoagulation is contraindicated

Original title: Percutaneous Left Atrial Appendage Closure With the AMPLATZER Cardiac Plug Device in Patients With Nonvalvular Atrial Fibrillation and Contraindication to Anticoagulation Therapy Reference: Marina Urena, et al. J Am Coll Cardiol 2013:62:96-102.   Anticoagulation is a good therapeutic strategy in nonvascular atrial fibrillation (AF). However, it is contraindicated in approximately 10% of patients, due to the...

Asymptomatic carotid injury, a disease not so silent

Original title: Association of the Recovery of Objective Abnormal CerebralPerfusion with Neurocognitive Improvement after CarotidRevascularization. Reference: Ching-Chang Huanget al. J Am CollCardiol 2013. Article in press. Cognitive impairment was observed in patients with severe asymptomatic carotid injury but a possible explanation for this is hyper-perfusion. Intuitively restored flow may improve neurocognitive capacity but so far studies have been...

Rational use of bivalirudin, less bleeding and less costs using risk score

Original title: Pre-Procedural Estimate of Individualized Bleeding Risk Impacts Physicians’ Utilization of Bivalirudin During Percutaneous Coronary Intervention. Reference: Seshu C. Rao et al. J Am Coll Cardiol 2013;61:1847–52 While safety of coronary angioplasty has improved over time, post-procedure bleeding  is still frequent with a large variability between centers. Bleeding is associated with increased mortality, myocardial infarction, stroke, increased...

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