CTO

Spontaneous coronary artery dissection (SCAD) is associated with fibro-muscular dysplasia in other territories

Original title: Spontaneous Coronary Artery Dissection. Prevalence of Predisposing Conditions Including Fibromuscular Dysplasia in a Tertiary Center Cohort Reference: Jacqueline Saw, et al. J Am Coll Cardiol Intv 2013;6:44 –52 Non atherosclerotic spontaneous coronary artery dissection (Non atherosclerotic SCAD) is a rare disease that is associated with acute myocardial infarction and sudden death.  This condition is more common...

Post TAVI LVEF Improvement: Only with No New Conduction Defects

Original title: Impact of a New Conduction Defect Alter Transcatheter Aortic Valve Implantation on Left Ventricular Function Reference: Rainer Hoffmann, et al. J Am Coll Cardiol Intv 2012;5:1257– 63. TAVI development in high risk patients can produce new conduction defects and require a definitive pacemaker in almost a third of treated patients.  The aim of this study was...

Aortic insufficiency has a poor prognosis in TAVI.

Original title: Impact of Post-Procedural Aortic Regurgitation on Mortality Alter Trancatheter Aortic Valve Implantation Reference: Kentaro Hayashida, et al. J Am Coll Interv 2012;5:1247-56 Transcatheter aortic valve implantation (TAVI) sprung up as a valid strategy to treat patients with severe high risk AS (aortic stenosis). However, residual aortic regurgitation (post AR) and post-dilation remain unsolved.  Between October 2006...

Periprocedural stroke, unrelated to the access site?

Original title: Influence of access site choice on incidence of neurologic complications after percutaneous coronary intervention. Reference: Karim Ratib et al. Am Heart J 2012;0:1-8 Article in press. Neurological complications post coronary angioplasty (PCA) are sporadic but they are associated with eight times increased mortality.  A transradial approach has multiple advantages over femoral but could theoretically have a...

Balloon Pulmonary Angioplasty (BPA) in patients with Chronic Thromboembolic Pulmonary Hypertension

Original title: Refined Balloon Pulmonary Angioplasty for Inoperable Patients with Chronic Thromboembolic Pulmonary Hypertension. Reference: Hiroki Mizoguchi et al. Circ Cardiovasc Interv. 2012;5:748-755. Patients with Chronic Thromboembolic Pulmonary Hypertension (CTE-PH) have bad prognosis. Pulmonary thromboendarterectomy can significantly reduce pulmonary pressure but, due to comorbidity or technical matters (very peripheral thrombi), not all patients are good candidates for this...

Thrombus Aspiration is useful in AMI

Original title: A Prospective Randomized Trial of Trombectomy Versus No Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesion. MUSTELA (MUltidevice Thrombectomy in Acute ST-Segment ELevation Acute Myocardial Infarction) Trial Reference: Marco De Carlo, et al. J Am Coll Cardiol Intv 2012;5:1223–30 The main objective during primary PCI is myocardial reperfusion, which is limited by distal...

Ambulatory Transradial Percutaneous Coronary Intervention

Original title: Ambulatory Transradial Percutaneous Coronary Intervention: A Safe, Effective, and Cost-Saving Strategy. Reference: Philippe Le Corvoisier et al. Catheterization and Cardiovascular Interventions 81:15–23 (2013). The number of PCI procedures has increased and for many interventional cardiology centers PC interventions entail significant resource consumption. Reducing post procedure hospital stay could reduce costs and optimize hospitalization resources.  The safety...

Chronic Total Occlusions, challenging but very possible

Original title: Predictors of Reocclusion After Successful Drug-Eluting Stent–Supported Percutaneous Coronary Intervention of Chronic Total Occlusion. The Florence CTO PCI Registry. Reference: Renato Valenti et al. J Am Coll Cardiol 2013; article in press. Previous registry data have shown a reduction in mortality rates in patients with successful recanalization of a Chronic Total Occlusion (CTO) compared to patients...

Revascularization reduces mortality in patients with high risk coronary artery disease based on multi-slice CT

Original title: All-cause mortality benefit of coronary revascularization vs. medical therapy in patients without known coronary artery disease undergoing coronary computed tomographic angiography: results from CONFIRM (Coronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter Registry) Reference: James K Min et al. European Heart Journal (2012) 33, 3088–3097 doi:10.1093/eurheartj/ehs315. Several large studies have shown revascularization reduces mortality...

Advances in Proximal Occlusion Devices for Carotid Angioplasty and Stenting

Original title: A Meta-Analysis of Proximal Oclusion Device Outcome in Carotid Artery Stenting Reference: Robert M Bersin, et al. Catheterization and Cardiovascular Intervention 80:1072-78 (2012) Carotid Angioplasty and Stenting (CAS) is considered a valid alternative to treat high risk patients. Embolic protection devices have been proved effective and currently there are two EPDs available: proximal occlusion and distal...

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