fractional flow reserve

A worse prognosis for incomplete revascularization in both angioplasty and surgery.

Original title: The Negative Impact of Incomplete Angiographic Revascularization on Clinical Outcomes and Its Association With Total Occlusions. The SYNTAX (Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) Trial. Reference: Vasim Farooq et al. J Am Coll Cardiol 2013;61:282–94 In patients with complex coronary artery disease who underwent coronary artery bypass surgery, (CABG), or percutaneous transluminal...

The FFR improves outcomes in daily practice as in randomized studies

Original title: Long-term outcomes of fractional flow reserve-guided vs. angiography-guided percutaneous coronary intervention in contemporary practice. Reference: Li J et al. Eur Heart J. 2013; Epub ahead of print Precision of the fractional flow reserve (FFR) to estimate the functional compromise of coronary stenosis and its ability to reduce events to decide PTCA, based on their outcome has...

Modest correlation between IVUS and FFR in intermediate lesions assessment

Original title: FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study Reference: Ron Waksman et al. J Am Coll Cardiol 2013. Article in Press For patients with angiographically assessed intermediate lesions such as stenosis between 40% and 80%, criteria that favor revascularization remains under debate.  Fractional Flow Reserve (FFR) is considered the gold standard to assess intermediate lesions,...

Incomplete Revascularization Linked With Mortality in Multivessel Disease Patients

Reference: Wu C, Dyer AM, Kinas SB, et al. Impact of incomplete revascularization on long-term mortality after coronary stenting. Circ Cardiovasc Interv 2011; 4: 413-21. Complete revascularization was defined as a reduction of stenosis to less than 50% in all diseased (≥ 70% stenosis) lesions in major epicardial coronary vessels at the initial hospitalization or within...

Intracoronary enalaprilat reduces periprocedural injury.

Original title: Intracoronary Enalaprilat to Reduce Microvascular Damage During Percutaneous Coronary Intervention (ProMicro) Study. Reference: Fabio Mangiacapra et al. J Am Coll Cardiol 2013. Article in press Angiotensin converting enzyme (ACE) inhibitors improve clinical outcomes in patients with coronary artery disease and improve epicardial flow in patients with acute ST-segment elevation.  Beyond the long-term protective effect of oral...

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