Resumen de las experiencias con Corevalve y nuevos dispositivos, tecnologías y desafíos para el implante percutáneo de válvula aórtica Dr. Elberhard Grube
CoreValve for High Risk and Extreme Risk Patients; The US Pivotal Trials
Eduardo de Marchena2014-10-30 M.D., F.A.C.C., F.A.C.P., F.S.C.A.I.Professor of Medicine & SurgeryAssociate Dean for International MedicineDirector of Interventional CardiologyUniversity of Miami Miller School of Medicine
Prótese Edwards Sapien XT e Medtronic Corevalve demonstram desempenho equivalente em 1 ano, em pacientes de alto risco submetidos a TAVI
Fundamentos: Existem poucos dados comparando diferentes próteses valvares (THV) utilizadas nos implantes percutâneos de valva aórtica (TAVI), sendo que as próteses balão expansíveis parecem apresentar melhores resultados em relação às balão-expansíveis. O objetivo do estudo foi comparar a performance hemodinâmica entre as próteses aórticas Edwards Sapien XT (balão-expansível) e Medtronic CoreValve (auto-expansível) em pacientes de...
CoreValve Evolut R CE: Good results at 6 months of the new CoreValve repositionable
This study evaluated the safety and efficacy of the new repositionable self-expanding valve. The primary end point was all-cause mortality and stroke at 30 days. 60 patients were included and the possibility for reposition was used 22 times between 12 recaptures and 10 re-sheathed of the valve. All maneuvers were carried out successfully. A 30...
ADVANCE II CoreValve Trial: Results at six months of self-expanding aortic valve
The CoreValve ADVANCE II Trial is a research study of the best practices to implement this device. Those practices included a careful assessment using scan to choose the right valve size, control the depth of the implant to 6 mm or less in relation to the valve annulus and adherence to international standards for pacemaker...
US CoreValve: Cost effectiveness of transcatheter replacement versus surgical replacement in high-risk patients
Previous studies have shown clinical benefits, but also an increased cost to treat patients with symptomatic severe aortic stenosis receiving transcatheter valve replacement (TAVR). There is little consensus regarding the cost-effectiveness for transcatheter versus surgical replacement. The present study was aimed to quantify the quality of life, adjusted survival for quality of life, resource utilization,...
CoreValve US Pivotal Trial: 2-year results of the self-expanding valve on inoperable patients
This study evaluated the safety and effectiveness of the CoreValve transcatheter valve replacement in patients with severe aortic stenosis with extreme risk for surgery. The primary end point was a composite of all-cause mortality and stroke at 24 months. The rate of death from any cause or cerebrovascular accident at 24 months was 38% for...
CoreValve superior to surgical aortic valve replacement in high-risk patients
The aim of this study was to compare percutaneous aortic valve replacement (TAVR) with the self-expanding Valve Core with conventional surgery in patients at high surgical risk. Patients with a valve area < 0.8 cm2 , valvular index ≤ 0.5 cm2 , a mean gradient of > 40 mmHg or peak speeds above 4m /s...
CHOICE Trial: Same mortality, less aortic regurgitation and need for a second prosthetic for Edwards Sapien XT valve versus Medtronic CoreValve
So far, there had been no published randomized studies comparing balloon-expandable Edwards’s prosthesis and self-expandingCoreValve. The aim of this study was to compare the results between the two thin aortic prosthesis in high-risk surgical patients with severe symptomatic aortic stenosis undergoing valve replacement by percutaneous transfemoral access. This was a multicenter work (five centers in...
COREVALVE EXTREME RISK: Promising results with CoreValve in very high-risk patients
Percutaneous aortic valve implantation ( TAVI ) recently demonstrated its superiority over medical treatment in patients with severe aortic stenosis and high surgical risk. Furthermore patients receiving TAVI showed a survival surgery equivalent to one year. This study included 471 patients with symptomatic severe aortic stenosis discarded of surgery due a very high risk. The...