Cardiovascular disease is the worldwide leading cause of death. Changes in lifestyle, diet and sedentary routine have increased risk factors. The age between 3 and 5 years is a great opportunity to intervene prospectively-effective to change lifestyle. The study was conducted in Colombia with preschool age children and intervention results were evaluated at 6-8 years...
Previous small studies have suggested that low-dose dopamine or neseritide can enhance congestive signs of acute heart failure without altering renal function. 360 patients were included within 24 hours of admission for heart failure with a glomerular filtration rate between 15 and 60 ml/min/1.73 m2. The primary endpoint was the improvement in the congestive signs...
SORT OUT V randomized trial (Odense University Hospital, Denmark) compared Nobori stent, a drug-eluting stent with biodegradable polymer eluting biolimus, versus CYPHER a drug-eluting stent with permanent polymer in the real world. Danish researchers used a non-inferiority design, by means of a primary objective of the study, the combined rate of major cardiac events (cardiac...
Spanish-Portuguese multicentre CIBELES study (Raul Moreno, Madrid, Spain) compared two drug-eluting stents – an everolimus (Xience V, Abbott Vascular, USA) and a sirolimus-releasing eluting stent (Cypher Select, Cordis Corporation, Miami Lakes, Florida, USA) in the context of total chronic coronary occlusions. With a non-inferiority design, the study randomized 208 patients (1:1), using as the primary...
It is shown that hypertension is associated with the occurrence of stroke but immediate treatment for an acute stroke itself is unclear. This study randomized 4071 acute stroke patients enrolled in an anti-hypertensive treatment (systolic pressure reduction by 10-25 % in the first 24 hours) versus control (stopping all antihypertensive drugs). The study included patients...
Randomized prospective study comparing the everolimus-eluting polymer-coated stent versus a biodegradable polymer with biolimus coated stent. While the use of first generation DES effectively reduces restenosis and reintervention rates, several meta-analyzes have shown a higher rate of late events of thrombotic origin associated with inflammatory phenomena and delayed reendothelialization at the site of implantation compared...
Read article James Mckenney.2012-03-25
Read article Michele Brignole.2012-03-25
Editorial Read article William Weintraub.2012-03-26
