DES

Renal angioplasty versus medical treatment, no clinical benefit and only a modest help to control blood pressure

Original title: Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis. CORAL trial. Reference: Christopher J. Cooper et al. DOI: 10.1056/NEJMoa1310753   Between 1 and 5% of the hypertensive population has renal artery stenosis and in general, this is combined with peripheral and coronary vascular disease. The renal artery stenosis may result in hypertension, ischemic nephropathy, and multiple long-term...

Noncardiac surgery is safe after 6 months after implantation of a DES

Original title: Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. Reference: Hawn MT et al. JAMA 2013;DOI:10.1001 In the patients who underwent non cardiac surgery and had coronary angioplasty with stent history  within 2 years there was not increased in major cardiac events (MACE ) with the exception of those who were...

Cilostazol reduces restenosis of DES in lesions larger than 40 mm.

Original title: Comparison of Dual Versus Triple Antiplatelet Therapy After Drug-Eluting Stent According to Stent Length (from the Pooled Analysis of DECLARE Trials). Reference: Seung-Whan Lee et al. Am J Cardiol 2013, article in press. Cilostazol, an inhibitor of phosphodiesterase III , associated with aspirin and clopidogrel showed decrease angiographic restenosis both in conventional stents as well as...

Paclitaxel eluting balloon . More effective in restenosis of BMS than DES

Original title: A multicenter randomized comparison of paclitaxel-coated balloon catheter with conventional balloon angioplasty in patients with bare-metal stent restenosis and drug-eluting stent restenosis. Referencia: Seiji Habara et al. Am Heart J 2013;166:527-533.e2. Paclitaxel – eluting balloons have recently emerged as an option for treating in-stent restenosis, both conventional stents ( BMS ) and with drugs (DES )....

DES versus Bare in primary angioplasty at five years. Initial advantage is reducing

Original: title Long-Term Outcome After Drug-Eluting VersusBare-Metal Stent Implantation in Patients WithST-Segment Elevation Myocardial Infarction. 5 Years Follow-Up From the Randomized DEDICATION (Drug Elution and DistalProtection in Acute Myocardial Infarction) Trial. Reference: Lene Holmvang et al. J Am CollCardiolIntv 2013, article in press.   Primary angioplasty reduced mortality and reinfarction compared with thrombolytics in patients experiencing an ST...

Double DES in bifurcations, double thrombosis risk

Original title: Late Thrombosis After Double Versus Single Drug-Eluting Stent in the Treatment of Coronary Bifurcations A Meta-analysis of Randomized and Observational Studies. Reference: Marco Zimarino et al. J Am Coll Cardiol Intv 2013. Article in press. In the era of drug-eluting stents, (DES), several randomized and observational studies have been conducted trying to find the best strategy...

Low Gradient Severe Aortic Stenosis despite Preserved Ejection Fraction

Original title: Invasive Hemodynamic Characteristics of Low Gradient Severe Aortic Stenosis Despite Preserved Ejection Fraction. Reference: Juliane Lauten et al. J Am Coll Cardiol 2013;61:1799–808. Although the pathophysiology, clinical features, and natural course of severe aortic stenosis have been extensively described, management recommendations are still evolving. The current European and American guidelines recommend a valve area cutoff of...

IVUS improves outcomes in long lesions with DES

Original title: Randomized Comparison of Clinical Outcomes between Intravascular Ultrasound and Angiography-Guided Drug-Eluting Stent Implantation for Long Coronary Artery Stenosis. Reference: Jung-Sun Kim et al. J Am Coll Cardiol Intv 2013. Article in press. Treating long lesions is difficult and the chance of instant thrombosis may be higher in these lesions. Coronary intravascular ultrasound (IVUS) can help in...

Modest correlation between IVUS and FFR in intermediate lesions assessment

Original title: FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study Reference: Ron Waksman et al. J Am Coll Cardiol 2013. Article in Press For patients with angiographically assessed intermediate lesions such as stenosis between 40% and 80%, criteria that favor revascularization remains under debate.  Fractional Flow Reserve (FFR) is considered the gold standard to assess intermediate lesions,...

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