Courtesy of Dr. Carlos Fava. Patients with severe mitral regurgitation unfit for surgery due to high surgical risk are likely to develop chronic kidney disease (CKD). There is limited information available on patients with CKD receiving MitraClip. This study analyzed patients receiving MitraClip and presenting chronic kidney disease. CKD was defined as a...
Original Title: Should Transcatheter Aortic valve replacement Be Performed in Nonagenarians? Insights from the STS/ACC TVT Registry. Reference: Mani Arsalan et al. J Am Coll Cardiol. 2016 Mar 29;67(12):1387-95. Courtesy of Dr. Carlos Fava The benefit of the transcatheter aortic valve replacement (TAVI) has already been shown in the general population undergoing this procedure. The number...
This study included 329 consecutive patients derived to coronary angiography based on myocardial perfusion tests or PET scan (positron emission tomography). The extension and severity of heart disease was assessed by angiography, and coronary flow reserve (CFR) was measured non-invasively by PET. After adjusting risk factors, ejection fraction, revascularization, etc, both the severity of angiographic...
The PARIS registry was a prospective observational study in 5018 patients undergoing coronary angioplasty with stent implantation in 15 centers. Three categories were prespecified in the discontinuation of dual antiplatelet therapy: 1) discontinuation for medical guidance, 2) transient discontinuation for less than 15 days for surgery and 3) permanent abandonment of it by non-adherence or...
There is little information about the use of bioresorbable vascular devices in patients with a reference diameter ≥4mm, long, bifurcation, calcified or unstable lesions. The BVS-Expand registry is a single-center study that evaluates the safety and efficacy of this device in past populations (real world).The primary endpoint was the occurrence of MACE (cardiac death, myocardial...
A small hole in the atrial septum can cause any severe neurological disorders, patent foramen ovale (PFO) – a cause or trigger that today can be given safe treatment without drug therapy for a long duration. Before birth there is a connection between the two atria, which closes immediately after birth, but for approximately 20%...
Bioengineers at the University of California, San Diego (USA) have shown in a study of pigs that a new injectable hydrogel can repair damage caused by heart attacks by helping to grow new tissue, blood vessels and heart. The results of the study, published in the “Science Translational Medicine” Journal, clear the way to begin...
Original title: Impact of chronic kidney disease on the outcome of transcatheter aortic valve implantation: results from the FRANCE 2 Registry. Reference: Atsushi Oguri, et al. EuroIntervention 2015;10:e1-9 Globally, 13% of patients present kidney failure, which has been associated to a worse evolution not only of TAVI outcomes but also of other cardiovascular intervention outcomes. Most studies, including...
Original title: Validation and Comparison of the Long-Term Prognostic Capability of SYNTAX Store-II Among 1528 Consecutive Patients Who Underwent Left Main Percutaneous Coronary Intervention. Reference: Bo Xu, et al. JACC Cardiovascular Intervention 2014;7:1128-37. The SYNTAX angiography score is useful when deciding revascularization in multivessel, but with the addition of clinical variables in the second version, SYNTAX score...
Original title: Initial German Experience With Tranapical Implantation of a Second-Generation Trascatheter heart Valve for the Treatment of Aortic Regurgitation. Reference: Moritz Seiffert, et al. JACC Cardiovasc Interv. 2014 Oct;7(10):1168-74. There is a group of patients with severe aortic regurgitation and they are not candidates for surgery; percutaneous implant is an option, but until now, there is little...