This work compared the safety and efficacy of the culotte technique versus the use of self-expanding Biolimus A9 (AXXESS) eluting stent evaluating the healing of the vessel by OCT besides quantitative angiography and clinical events. In one, group (n = 20) bifurcated stent system AXXESS plus everolimus-eluting stents in the main distal branch and side...
Bruckheimer, Elchanan (Israel)2014-04-25
Dangas , George D. (USA)2014-04-25
This multicenter work from Japanrandomized 3200 patients to receive biodegradable polymer biolimus eluting stent(Nobori) or everolimus-eluting stent with permanent polymer (Xience / Promus). The primary end point for efficacy was any revascularizationlesion. A two year follow up the Nobori stent was non-inferior to death or myocardial infarction (7.83% versus 7.69%) and TLR (6.23% versus 5.95%). ...
The use of drug-eluting stents versus bare metal stents is controversial in some clinical situations in patients at high risk of bleeding.This study randomized 1606 patients considered at low risk of restenosis but with high risk of bleeding receiving Zotarolimus eluting stent (Endeavor) or conventional stent.The clinical characteristics were similar between the two groups with...
SORT OUT V randomized trial (Odense University Hospital, Denmark) compared Nobori stent, a drug-eluting stent with biodegradable polymer eluting biolimus, versus CYPHER a drug-eluting stent with permanent polymer in the real world. Danish researchers used a non-inferiority design, by means of a primary objective of the study, the combined rate of major cardiac events (cardiac...
The EVOLUTION study, (Dr. Junbo Ge, Shanghai Institute, China), compared two sirolimus-eluting stents, one with permanent polymer (Cypher Select, Cordis Corporation, Miami Lakes, Florida, USA) and another with degradable polymer (Excel, JW Medical System Ltd, Weihai, China). A randomized (2:1) was used, open and non-inferiority, including 1923 patients in 30 centers in China (December 2008...
Professor Serruys presented the results of the TROFI trial that compares the minimal intra-stent flow area in STEMI patients post primary PCI with or without manual thrombus aspiration. The minimal intra-stent flow area helps assess thrombus burden and is defined as: (stent area + incomplete stent apposition area) – (intralulminal defect area attached to the...
CLI-randomized study CLI-OPCI (n = 670, 1:1) evaluated the impact of stent implantation guided by angiography and optical coherence tomography (OCT), versus angioplasty guided alone by angiography. All patients who had been subjected to stent placement were then evaluated by angiography. Arm OCT, after an optimal angiographic result, an intracoronary OCT evaluation was performed. In...
The DISCOVER FLOW trial has recently showed an excellent correlation between fractional flow reserve values (FFR) traditionally obtained with coronary CT angiography (CCTA) and the ones obtained with a non invasive technology derived from multi slice computerized tomography (MSCT). Researchers used a novel technology that allows deriving non invasive FFR from MSCT data. Dr. Bon-Kwon...