Courtesy of Dr. Carlos Fava. In most randomized or observational studies, women comprise more than 50% of patients undergoing TAVR, and they have showed better evolution, compared against surgery. The main differences between men and women with severe aortic stenosis are that women have smaller annular dimension, shorter distance to coronary ostia, smaller peripheral arteries, and<a href="https://solaci.org/en/2018/01/24/win-tavi-the-largest-female-tavr-registry-so-far/" title="Read more" >...</a>
What Is the Long-Term Outcome of Lesions Deferred Using FFR/iFR?
The presence of inducible ischemia is an essential prerequisite to obtain clinical benefits from revascularization through angioplasty. In that sense, the measurement of fractional flow reserve (FFR) is the gold standard as regards invasive methods assessing the functional significance of epicardial artery stenosis. As opposed to FFR, the measurement of the instantaneous wave-free ratio (iFR)<a href="https://solaci.org/en/2018/01/18/what-is-the-long-term-outcome-of-lesions-deferred-using-ffr-ifr/" title="Read more" >...</a>
iFR in Nonculprit Lesions: Measurement Timing May Change History
During primary angioplasty, it is not uncommon to see several other lesions in coronary arteries. Current guidelines advise against the treatment of these lesions in the same primary angioplasty procedure, although there is evidence supporting such a course of action that may warrant changes in these recommendations. The functional assessment of these nonculprit lesions may<a href="https://solaci.org/en/2017/12/19/ifr-in-nonculprit-lesions-measurement-timing-may-change-history/" title="Read more" >...</a>
How Is Renal Function Affected by Endoprosthesis Implantation?
The occurrence of renal failure after any endovascular intervention is associated with increased morbility and mortality. After a coronary intervention (whether it be angioplasty or surgery), renal failure increases mortality 20-fold. Relatedly, surgical repair of an abdominal aortic aneurysm with renal failure is also associated with a significant increase in the number of events. Read<a href="https://solaci.org/en/2017/12/14/how-is-renal-function-affected-by-endoprosthesis-implantation/" title="Read more" >...</a>
Non-Invasive FFR: CT Evolves from Anatomical to Functional
In the US, more than 4 million patients with chronic stable angina are looking to rule out heart disease. Most undergo functional diagnostic studies that might lead to invasive coronary angiography followed by revascularization. CT has become an alternative diagnostic tool thanks to its precision to rule out heart disease (negative predictive value between 97<a href="https://solaci.org/en/2017/12/01/non-invasive-ffr-ct-evolves-from-anatomical-to-functional/" title="Read more" >...</a>
7 articles on angioplasty that can draw your attention
1) Balloon Angioplasty: A Reasonable Plan B for Chronic Thromboembolic Hypertension Thromboembolic pulmonary hypertension is caused by pulmonary artery stenosis caused by organized thrombi. The only treatment potentially healing for this disease is surgical thrombectomy. However, patients with lesions in very peripheral branches or high surgical risk patients with comorbidities might benefit from a plan B,<a href="https://solaci.org/en/2017/11/27/7-articles-on-angioplasty-that-can-draw-your-attention/" title="Read more" >...</a>
DKCRUSH-V: Left Main, Not Just Another Bifurcation
Cardiac Artery Bypass Graft Surgery has been shown more effective than percutaneous coronary intervention (basically because it renders lower revascularization rate) in patients with severe left main bifurcation lesions receiving 1st generation drug eluting stents. This is why the 2014 American guidelines recommend CABG for most patients. But the EXCEL and the NOBLE trials brought back hope to<a href="https://solaci.org/en/2017/11/22/dkcrush-v-left-main-not-just-another-bifurcation/" title="Read more" >...</a>
Efficacy of Micromesh-Covered Stents in Carotid Artery Stenting
Most literature, old and recent, associates carotid artery stenting with a higher rate of stroke (although minor) when compared with carotid endarterectomy during the acute period. However, 30-day outcomes of angioplasty and surgery are comparable. Many technical advancements, including new stent designs and different cerebral protection mechanisms, have improved the outcomes of angioplasty in clinical<a href="https://solaci.org/en/2017/11/10/efficacy-of-micromesh-covered-stents-in-carotid-artery-stenting/" title="Read more" >...</a>
EXCEL-QOL Substudy: Similar Quality of Life both with CABG and Left Main PCI
Courtesy of SBHCI. According to a new quality of life sub-study, the “EXCEL”, both coronary artery bypass graft and left main PCI are associated with significant clinical improvement in terms of angina frequency, tolerance to exertion and treatment satisfaction. At 12 and 36 months, there were no significant differences between PCI and surgery after several quality of<a href="https://solaci.org/en/2017/11/01/excel-qol-substudy-similar-quality-of-life-both-with-cabg-and-left-main-pci/" title="Read more" >...</a>
2.0-mm DES for Very Small Vessels: Are They Viable?
The reference vessel diameter is a fundamental factor for restenosis after coronary angioplasty even with drug-eluting stents. The smallest sized stents available are 2.25 mm in diameter, but even smaller vessels can be symptomatic. This was a prospective multicenter trial of the Resolute Onyx 2.0-mm zotarolimus-eluting stent. The primary endpoint was target lesion failure. Read also: “Effects<a href="https://solaci.org/en/2017/10/25/2-0-mm-des-for-very-small-vessels-are-they-viable/" title="Read more" >...</a>