coronary stenosis

IVUS-XPL: IVUS superior to angiography for guiding DES implantation in long lesions

Original Title: Effect of intravascular ultrasound-guided vs angiography-guided everolimus-eluting stent implantation: the IVUS-XPL randomized clinical trial. Presenter: Hong S-J. Patients with long coronary lesions have better clinical results after a year of second generation DES implantation when interventions are guided by IVUS, instead of angiography. The benefit was attributed to a lower revascularization rate of ischemia<a href="https://solaci.org/en/2015/11/20/ivus-xpl-ivus-superior-to-angiography-for-guiding-des-implantation-in-long-lesions/" title="Read more" >...</a>

FAME at 5 years: FFR Should Guide All Multivessel PCIs

Though the benefit of FFR (fractional flow reserve) over angiography is statistically important only over the first 2 years, this pattern is maintained at long term according to FAME 5 year follow up, presented at the ECS and simultaneously published in The Lancet. Between the second and fifth year, the number of patients at risk<a href="https://solaci.org/en/2015/11/16/fame-at-5-years-ffr-should-guide-all-multivessel-pcis/" title="Read more" >...</a>

ILUMIEN II: OCT guided stenting versus IVUS

The main predictor of adverse outcomes (thrombosis and restenosis) after implantation of a stent is the degree of expansion according to published studies using coronary intravascular ultrasound (IVUS). It is unknown whether optical coherence tomography (OCT), in this sense, provides similar information as the IVUS. The aim of this study was to compare the degree<a href="https://solaci.org/en/2015/06/24/ilumien-ii-oct-guided-stenting-versus-ivus/" title="Read more" >...</a>

OCT-STEMI: Primary angioplasty guided by OCT

This study included 201 patients suffering ST-segment elevation acute coronary syndrome and randomized to the use of optical coherence tomography (OCT) versus conventional angiography for the procedure. OCT-guided group used more stents per patient (1.4 versus 1.2, p = 0.03) and greater release pressure. During control OCT suboptimal results were found in a third of<a href="https://solaci.org/en/2015/06/24/oct-stemi-primary-angioplasty-guided-by-oct/" title="Read more" >...</a>

FAME II: This randomized trial compared a stent implantation guided by fractional flow reserve (FFR) with optimal medical treatment.

This randomized trial with an initial plan to include 1832 patients, compared stent implantation guided by fractional flow reserve (FFR) versus optimal medical treatment. In this study, we invasively evaluated the severity of lesion by FFR. Of this population, only patients who had lesions with significant translesional gradient (FFR &lt;0.9) were included in the study<a href="https://solaci.org/en/2015/06/24/fame-ii-this-randomized-trial-compared-a-stent-implantation-guided-by-fractional-flow-reserve-ffr-with-optimal-medical-treatment/" title="Read more" >...</a>

DESolve I FIM: Evaluation of a FIM trial results of a bioabsorbable stent (15 patients).

&nbsp;This trial is a prospective evaluation of DESolveTM bioabsorbable coronary stent implantation in a 15 patient cohort enrolled in New Zealand and Belgium. At 6 months follow up, late lumen loss was 0,19 mm, binary restenosis was 0% and thrombosis was absent. OCT evaluation showed excellent stent apposition, and 98% of evaluated struts were covered<a href="https://solaci.org/en/2015/06/24/desolve-i-fim-evaluation-of-a-fim-trial-results-of-a-bioabsorbable-stent-15-patients/" title="Read more" >...</a>

CLI-OPCI: Optical coherence tomography (OCT)-guided stent implantation vs. conventional angiography guided angioplasty.

CLI-randomized study CLI-OPCI (n = 670, 1:1) evaluated the impact of stent implantation guided by angiography and optical coherence tomography (OCT), versus angioplasty guided alone by angiography. All patients who had been subjected to stent placement were then evaluated by angiography.&nbsp; Arm OCT, after an optimal angiographic result, an intracoronary OCT evaluation was performed. In<a href="https://solaci.org/en/2015/06/24/cli-opci-optical-coherence-tomography-oct-guided-stent-implantation-vs-conventional-angiography-guided-angioplasty/" title="Read more" >...</a>

XIMA: Randomized prospective study comparing everolimus eluting stents versus conventional stent implantation in octogenarians.

Background: Octogenarian patients represent an increasingly growing population. In addition, this age group has a higher proportion of co-morbidities with more extensive and complex coronary disease. However, they have often been excluded from major studies, whose average age is usually 60 years. Despite having a more complex coronary anatomy, the role of pharmacological stent (DES)<a href="https://solaci.org/en/2015/06/24/xima-randomized-prospective-study-comparing-everolimus-eluting-stents-versus-conventional-stent-implantation-in-octogenarians/" title="Read more" >...</a>

CENTURY: new clinical results of sirolimus-eluting degradable polymer stent

This new stent is a sirolimus-eluting low-profile cobalt chrome platform (80 &micro;m) with a rapid resorption polymer (3 months). Theoretically, it presents less risk of inflammation of the vessel due to the kinetics of drug elution and polymer degradation. The objective of this study was to test the safety and efficacy of the new device.<a href="https://solaci.org/en/2015/06/24/century-new-clinical-results-of-sirolimus-eluting-degradable-polymer-stent/" title="Read more" >...</a>

BIOSS: results of the new drug-eluting stent for bifurcations

This new device is a stainless steel platform of 120 &micro;m thick with a sirolimus-eluting bio-absorbable polymer. It has two separate parts: a larger diameter proximal part and a smaller diameter distal part connected by two 1.2 mm structures. The objective of this study was to test (first in man) the device in bifurcations. We<a href="https://solaci.org/en/2015/06/24/bioss-results-of-the-new-drug-eluting-stent-for-bifurcations/" title="Read more" >...</a>

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