Original title: Incidence and predictors of stent trombosis: a single-centre study of 5833 consecutive patients undergoing coronary artery stenting Reference: Javaid Iqbal et al. EuroInterventional 2013;9:62-69 Though potentially fatal, stent thrombosis is a low frequency event associated to stent malapposition, fractures, resistance to antiplatelet therapies, and diseases such as diabetes and kidney disease, among other factors. 5883 pacients...
Original title: Residual SYNTAX score after PCI for triple vessel coronary artery disease: quantifying the adverse effect of incomplete revascularisation. Reference: Christopher J. Malkin et al. EuroIntervention 2013;8:1286-1295. In the angioplasty branch of the SYNTAX study, complete revascularization was reached in 56.7% of the population. On the other hand, in the real world, around 40% of patients that...
Original title: Percutaneous Left Atrial Appendage Closure for Stroke Prophylaxis in Patients With Atrial Fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) Trial. Reference: Vivek Y. Reddy et al. Circulation. 2013;127:720-729. Atrial fibrillation is the most common sustained arrhythmia in the world and its importance lies...
Original title: Renal Sympathetic Denervation for Treatment of Drug-Resistant Hypertension Clinical Perspective Reference: Murray D. Ester et al. Circulation 2012; 126: 2976-2982 Renal sympathetic activation contributes to the pathogenesis of hypertension. The Symplicity HTN – 2 was a multicenter, randomized study which demonstrated that renal denervation produced a significant decrease in blood pressure at 6 months in patients...
Original title: Characteristics of Ischemic Brain Lesions After Stenting or Endarterectomy for Symptomatic Carotid Artery Stenosis : Results From the International Carotid Stenting Study-Magnetic Resonance Imaging Substudy (ICSS-MRI). Reference: Henrik Gensicke et al. Stroke 2013;44:80-86. This work is a sub-study using magnetic resonance imaging (MRI) of the International Carotid Stenting Study (ICSS) that randomized carotid angioplasty (CAS) or...
Original title: Strategies for Multivessel Revascularization in Patients with Diabetes. The FREEDOM Trial. Reference: Michael E. Farkouh et al. N Engl J Med 2012. DOI: 10.1056/NEJMoa1211585 This study was designed to determine the best revascularization strategy in diabetic patients with multivessel using current techniques of angioplasty (PCI) and surgery (CABG). Randomized 1:1 diabetic patients with injuries > 70%...
Reference: Généreux, et al, for the PARTNER Trial Investigators. JACC 2012; 60 (12):1043-62 Original title: Vascular complications after Transcatheter Aortic Valve Replacement: Insights From the PARTNER (Placement of AoRTic TraNscathetER Valve) Trial The purpose of the study was to investigate the incidence, predictors and vascular complications impact after catheter aortic valve implantation (TAVI) in the PARTNER...
Reference: Planer et al. International Journal of Cardiology 2012 (in press) Prognosis of patients enrolled in acute myocardial infarction with ST segment elevation (STEMI) has improved markedly, particularly as a result of reperfusion therapy. Despite these improvements, patients with diabetes mellitus (DM) are a high risk group in the short and long term compared with...