primary angioplasty

Colchicine could reduce restenosis in diabetic patients treated with BMS

Original title: Colchicine Treatment for the Prevention of Bare-Metal Stent Restenosis in Diabetic Patients. Reference: Spyridon Deftereos et al. J Am Coll Cardiol 2013;61:1679–85. In stent restenosis is more frequent in diabetic patients, who therefore find DES particularly beneficial. However, there is a subset of these patients with contraindication to prolonged double antiaggregation, due to a programmed surgery...

More evidence for drug eluting balloons in the femoropopliteal region

Original title: 2-Year Results of Paclitaxel-Eluting Balloons for Femoropopliteal Artery Disease. Evidence From a Multicenter Registry. Reference: Antonio Micari et al. J Am Coll Cardiol Intv 2013;6:282–9. Paclitaxel-eluting balloons appear safe and effective for treating atherosclerotic lesions in the femoropopliteal region, leaving the stent only as a rescue strategy against a suboptimal outcome. However, the vast majority of...

IVUS improves outcomes in long lesions with DES

Original title: Randomized Comparison of Clinical Outcomes between Intravascular Ultrasound and Angiography-Guided Drug-Eluting Stent Implantation for Long Coronary Artery Stenosis. Reference: Jung-Sun Kim et al. J Am Coll Cardiol Intv 2013. Article in press. Treating long lesions is difficult and the chance of instant thrombosis may be higher in these lesions. Coronary intravascular ultrasound (IVUS) can help in...

The largest series of femoropopliteal in-stent restenosis to date 

Original title: Treatment of Femoropopliteal In-Stent Restenosis With Paclitaxel-Eluting Stents. Zilver PTX Global Registry. ZILVER-PTX. Reference: Thomas Zeller et al. J Am Coll Cardiol Intv 2013;6:274–81. Femoropopliteal in-stent restenosis (ISR) is reported in between 19% and 37% of lesions a year and this incidence increases with lesion length.  The ZILVER-PTX study tested the self-expanding paclitaxel-eluting nitinol stent (Cook...

A moderate dose of midazolam and fentanyl is effective in reducing radial spasms 

Original title: Moderate Procedural Sedation and Opioid Analgesia During Transradial Coronary Interventions to Prevent Spasm. A Prospective Randomized Study. Reference: Spyridon Deftereos et al. J Am Coll Cardiol Intv 2013;6:267–73. The trans-radial approach has become the preferred diagnostic and therapeutic study for evidence of minor vascular complications, shorter hospital stays, less blood loss and better outcomes in acute...

A moderate dose of midazolam and fentanyl is effective in reducing radial spasms 

Original title: Moderate Procedural Sedation and Opioid Analgesia During Transradial Coronary Interventions to Prevent Spasm. A Prospective Randomized Study. Reference: Spyridon Deftereos et al. J Am Coll Cardiol Intv 2013;6:267–73. The trans-radial approach has become the preferred diagnostic and therapeutic study for evidence of minor vascular complications, shorter hospital stays, less blood loss and better outcomes in acute...

Paclitaxel eluting balloon in the femoropopliteal region

Original title: Paclitaxel-Coated Versus Uncoated Balloon Angioplasty Reduces Target Lesion Revascularization in Patients With Femoropopliteal Arterial Disease. A Meta-Analysis of Randomized Trials. Reference: Salvatore Cassese et al. Circ Cardiovasc Interv. 2012;5:582-589. Balloon angioplasty is one of the most frequent alternatives used in patients with peripheral vascular disease, especially in the femoropopliteal region.  However, its effectiveness is reduced in...

Women have a higher mortality rate in ST-segment elevation acute myocardial infarction 

Original title: Is the difference in outcome between men and women treated by primary percutaneous coronary intervention age dependent?: Gender difference in STMI stratified on age Reference: Amber M Otten et, al.European Heart Journal Acute Cardiovascular Care January 31:1-8 Numerous publications have shown that women have worse outcomes than men in chronic ischemic heart disease but their evolution...

Stent implantation in the popliteal artery is feasible.

Original title: Treatment of Complex Atherosclerotic PoplitealArtery Disease With a New Self-Expanding Interwoven Nitinol Stent. 12-Month Results of the Leipzig SUPERA Popliteal Artery Stent Registry. Reference: Dierk Scheinert, et al. J Am Coll Cardiol Intv 2013;6:65–71 Currently, peripheral angioplasty (PTA) of the popliteal artery is a real challenge since stent implantation is controversial and the outcome of balloon...

Revascularization reduces mortality in patients with high risk coronary artery disease based on multi-slice CT

Original title: All-cause mortality benefit of coronary revascularization vs. medical therapy in patients without known coronary artery disease undergoing coronary computed tomographic angiography: results from CONFIRM (Coronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter Registry) Reference: James K Min et al. European Heart Journal (2012) 33, 3088–3097 doi:10.1093/eurheartj/ehs315. Several large studies have shown revascularization reduces mortality...

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