Courtesy of the SBHCI. Intrepid is a 43-, 46-, and 50-mm nitinol self-expanding valve with bovine pericardial leaflets that is placed using a transapical delivery system with a 35-Fr access. This pilot study enrolled 50 patients with severe mitral regurgitation who were symptomatic and at a high surgical risk, or in whom surgery was contraindicated. Read...
Courtesy of Dr. Carlos Fava The EVEREST II trial showed the MitraClip had similar mortality rate to that of surgery but, even though residual mitral valve regurgitation (MR) is associated to a strong negative impact, little is known about post MitraClip increased transvalvular gradient and its implication. 268 patients undergoing MC implantation were analyzed....
Courtesy of Dr. Carlos Fava. Aortic valve calcification and mitral annular calcification have the same etiology and are frequently present in high-risk patients undergoing transcatheter aortic valve replacement (TAVR). The implications of mitral annular calcification for patients undergoing TAVR has not been entirely clarified yet. The study examined 782 patients with severe aortic stenosis who underwent...
Courtesy of Dr. Carlos Fava. This study sought to analyze the clinical impact and the level of improvement of mitral regurgitation (MR) in patients who receive a transcatheter aortic valve replacement (TAVR), and to find potential candidates for double valve repair with percutaneous techniques. Of 1.110 patients included, 177 (15.9%) suffered from severe pre-TAVR mitral...
Fundamentos: A regurgitação mitral severa (MR) representa a segunda doença cardíaca valvar mais prevalente nos países ocidentais. De um terço a metade dos pacientes que necessitam de reparo da valva mitral / substituição são considerados de muito alto risco para cirurgia. O procedimento percutâneo mitral de reparo de borda a borda surgiu como uma alternativa...
Original title: Multicenter Evaluation of a Next-Generation Balloon-Expandable Transcatheter Aortic Valve. Reference: John Webb, et al. J Am Coll Cardiol 2014;64:2235-43 Percutaneous aortic valve replacement is starting to be a reasonable alternative in patients at intermediate risk. One hundred and fifty patients who received SAPIEN 3rd generation percutaneous aortic valve implantation were analyzed prospectively. The STS score of...
Original title: 4-Year Results of a Randomized Controlled Trial of Percutaneous Repair Versus surgery for Mitral Regurgitation. Reference: Laura Mauri, et al. J Am Coll Cardiol 2013;62:317-28 Surgical treatment of mitral regurgitation (MR) is currently recommended by either valve replacement or valvuloplasty. Devices are being developed to address this disease giving the benefits of percutaneous treatments. The EVEREST...
Original title: 5 Years Experience With Trancatheter Tranaspical Mitral Valve –in Valve Implantation for Bioprosthetic Valve Dysfunction Reference: Anson Cheung et al. J Am Coll Cardiol 2013;61:1759–66. Percutaneous valves development, first aortic and now mitral, has brought an opportunity to improve life quality and extend life for high risk non-surgical patients. 23 patients received transapical implantation in mitral...
Original title: Acute Severe Mitral Regurgitation Following Balloon Mitral Valvulotomy: Echocardiographic Feature, Operative Finfing and Outcome in 50 Surgical Cases. Reference: Manjunath C. Nanjappa, et al. Catherization and Cardiovascular Intervention 81:603-608 (2013) Severe Mitral Insufficiency Following Mitral Valvotomy (VPM) is a major complication; though not frequent, (0.9%-2%) it is life threatening and requires resolution through valve replacement. The...
Reference: Durand E. et al (JACC CV interventions 2012 in press)1 When percutaneous aortic valve replacement (AVR) first began the procedure required a large-bore sheath (22-24 F), being the most frequent surgical strategy when using general anesthesia. Continuous technological advances achieved the miniaturization of devices which allow the procedure to be performed with a much...