Direct Stent, no clinical utility in patients undergoing elective

 Original title: The Independent Value of a Direct Stenting Strategy on Early and Late Clinical Outcomes in Patients Undergoing Elective Percutaneous Coronary Intervention. Reference: Gabriel L. Sardi et al. Catheterization and Cardiovascular Interventions 81:949–956 (2013).   The use of direct stenting (DS) without pre-stenting dilation has proven to be a safe strategy, especially with the<a href="https://solaci.org/en/2013/06/18/direct-stent-no-clinical-utility-in-patients-undergoing-elective/" title="Read more" >...</a>

Adenosine, the best vasodilator to improve blood flow in primary angioplasty

Original title: Open Label, Randomized, Placebo-Controlled Evaluation of Intracoronary Adenosine or Nitroprusside Alter Thrombus Aspiration During Primary Percutaneous Coronary Intervention for the Prevention of Microvascular Obstruction in Acute Myocardial Infartion . The Reopen-AMI Study Reference: Giampaolo Niccoli, et al. J Am Coll Cardiol Intv 2013. Article in Press One of the challenges of PCI is to achieve the<a href="https://solaci.org/en/2013/06/13/adenosine-the-best-vasodilator-to-improve-blood-flow-in-primary-angioplasty/" title="Read more" >...</a>

A real challenge: Primary PCI on an Unprotected Left Main Coronary Culprit Lesion

Original title: A Systematic Review and Meta-Analysis on Primary Percutaneous Coronary Intervention on an Unprotected Left Main Coronary Artery Culprit Lesion in the setting of Acute Myocardial Infarction Reference: Marije M. Vis et al. J Am Coll Cardiol Intv 2013;6:317–24 Acute myocardial infarction with a significantly compromised unprotected left main coronary artery culprit lesion is relatively rare (4%<a href="https://solaci.org/en/2013/04/24/a-real-challenge-primary-pci-on-an-unprotected-left-main-coronary-culprit-lesion/" title="Read more" >...</a>

MitraClip® in real life

Original title: Acute outcomes after MitraClip® therapy in highly aged patients: results from the German TRAnscatheter Mitral valve Interventions (TRAMI) Registry. Reference: Wolfgang Schillinger et al. EuroIntervention 2013; 8-online publish-ahead-of-print April 2013. Recently, percutaneous repair of the mitral valve with MitraClip®, (Abbott Vascular, Santa Clara, CA, USA), has emerged as an option for patients with severe mitral regurgitation,<a href="https://solaci.org/en/2013/04/17/mitraclip-in-real-life/" title="Read more" >...</a>

5 Year Follow Up Outcome of Zotarolimus Eluting Stent

Original title: The “Final” 5-Year Follow-Up From the ENDEAVOR IV Trial Comparing a Zotarolimus-Eluting Stent With a Paclitaxel-Eluting Stent. ENDEAVOR IV Investigators Reference: Ajay J. Kirtane et al. J Am Coll Cardiol Intv 2013. Article in press. The ENDEAVOR IV was a randomized controlled study with a noninferiority design that compared the Endeavor zotarolimus eluting stent (Medtronic, Santa<a href="https://solaci.org/en/2013/04/12/5-year-follow-up-outcome-of-zotarolimus-eluting-stent/" title="Read more" >...</a>

Complete revascularization in one procedure is more cost effective and as safe as in stages.

Original title: Staged Versus One-time Complete Revascularization With Percutaneous Coronary Intervention for Multivessel Coronary Artery Disease Patients Without ST-Elevation Myocardial Infarction. Reference: Edward L. Hannan et al. Circ Cardiovasc Interv 2013;6;12-20. There is evidence that in patients with multi-vessel disease affected by an acute coronary syndrome (ACS) with ST segment elevation, only the cause lesion should be treated<a href="https://solaci.org/en/2013/03/04/complete-revascularization-in-one-procedure-is-more-cost-effective-and-as-safe-as-in-stages/" title="Read more" >...</a>

Ischemic preconditioning reduces infarct size in patients treated with primary angioplasty

Original title: Preinfarction Angina Reduces Infarct Size in ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention Reference: Ronald Reiter et al. Circ Cardiovasc Interv. 2013;6:00-00. Ischemic preconditioning (IPC) is a phenomenon whereby transitory ischemia episodes protect the myocardium against a more prolonged episode.  Until now, IPC has been the most effective approach to protect the myocardium. Pre infarction<a href="https://solaci.org/en/2013/02/08/ischemic-preconditioning-reduces-infarct-size-in-patients-treated-with-primary-angioplasty/" title="Read more" >...</a>

Spontaneous coronary artery dissection (SCAD) is associated with fibro-muscular dysplasia in other territories

Original title: Spontaneous Coronary Artery Dissection. Prevalence of Predisposing Conditions Including Fibromuscular Dysplasia in a Tertiary Center Cohort Reference: Jacqueline Saw, et al. J Am Coll Cardiol Intv 2013;6:44 –52 Non atherosclerotic spontaneous coronary artery dissection (Non atherosclerotic SCAD) is a rare disease that is associated with acute myocardial infarction and sudden death.  This condition is more common<a href="https://solaci.org/en/2013/01/24/spontaneous-coronary-artery-dissection-scad-is-associated-with-fibro-muscular-dysplasia-in-other-territories/" title="Read more" >...</a>

Intracoronary enalaprilat reduces periprocedural injury.

Original title: Intracoronary Enalaprilat to Reduce Microvascular Damage During Percutaneous Coronary Intervention (ProMicro) Study. Reference: Fabio Mangiacapra et al. J Am Coll Cardiol 2013. Article in press Angiotensin converting enzyme (ACE) inhibitors improve clinical outcomes in patients with coronary artery disease and improve epicardial flow in patients with acute ST-segment elevation.  Beyond the long-term protective effect of oral<a href="https://solaci.org/en/2013/01/22/intracoronary-enalaprilat-reduces-periprocedural-injury/" title="Read more" >...</a>

Thrombus Aspiration is useful in AMI

Original title: A Prospective Randomized Trial of Trombectomy Versus No Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesion. MUSTELA (MUltidevice Thrombectomy in Acute ST-Segment ELevation Acute Myocardial Infarction) Trial Reference: Marco De Carlo, et al. J Am Coll Cardiol Intv 2012;5:1223–30 The main objective during primary PCI is myocardial reperfusion, which is limited by distal<a href="https://solaci.org/en/2013/01/10/thrombus-aspiration-is-useful-in-ami/" title="Read more" >...</a>