Original Title: Regression of Paravalvular Aortic Regurgitation and Remodeling of Self-Expanding Transcatheter Aortic Valve. An Observation From the CoreValve U.S. Pivotal Trial. Reference: Jae K. Oh et al. J Am Coll Cardiol Img. 2015, online first. The aim of this study was to describe the natural evolution and the clinical significance of paravalvular aortic insufficiency after...
Percutaneous Treatment of Mitral Regurgitation
Igor F. Palacios2014-08-08 Director of Interventional CardiologyMassachusetts General HospitalProfessor of MedicineHarvard Medical School
Mitral valve repair in moderate ischemic mitral regurgitation
Article Up to 50% of acute myocardial infarctions are associated to mitral regurgitation of some degree and 10% of these cases present, at least, moderate regurgitation. Ischemic mitral regurgitation is associated to an increase of mortality and morbidity. For surgical patients with moderate regurgitation, the benefits mitral valve repair remain unclear. 301 patients were randomized...
SALUS: New percutaneous valve with promising results regarding aortic regurgitation post implant.
Aortic regurgitation after valve implantation has been shown to be a long -term mortality predictor. The aim of this study was to test the new Direct Flow Medical system, which is more flexible prosthesis with a lower profile that could result in minor aortic regurgitation and less need for post expansion. This multicenter study included...
CHOICE Trial: Same mortality, less aortic regurgitation and need for a second prosthetic for Edwards Sapien XT valve versus Medtronic CoreValve
So far, there had been no published randomized studies comparing balloon-expandable Edwards’s prosthesis and self-expandingCoreValve. The aim of this study was to compare the results between the two thin aortic prosthesis in high-risk surgical patients with severe symptomatic aortic stenosis undergoing valve replacement by percutaneous transfemoral access. This was a multicenter work (five centers in...
Plastic versus mitral valve replacement in ischemic mitral regurgitation
Unlike degenerative mitral insufficiency, ischemic failure is due to an increase in the left ventricular cavity, the loss of its elliptical form, ring dilation and displacement of the papillary muscles leading to the loss of coaptation the leaflets. European and American guidelines suggest the intervention on the mitral valve in patients with ischemic mitral regurgitation...
DISCOVER: new low profile valve with little post-implant regurgitation
The objective of the study was to assess events after 30 days with the DirectFLOW Medical Valve device in patients with severe aortic stenosis and high surgical risk. The device is designed to reduce post-implant aortic regurgitation; it has a low profile and high navigability and requires no post-dilatation or rapid pacing. The study included...
TAVI, also a promising option for severe aortic regurgitation
Original title: Initial German Experience With Tranapical Implantation of a Second-Generation Trascatheter heart Valve for the Treatment of Aortic Regurgitation. Reference: Moritz Seiffert, et al. JACC Cardiovasc Interv. 2014 Oct;7(10):1168-74. There is a group of patients with severe aortic regurgitation and they are not candidates for surgery; percutaneous implant is an option, but until now, there is little...
Similar mortality outcomes with MitraClip and surgery in high risk patients with severe mitral valve regurgitation
Original title: Survival of transcatheter mitral valve repair compared with surgical and conservative treatment in high-surgical-risk patients. Reference: Swaans MJ et al. J Am CollCardiolIntv. 2014;7:875-881. In high-surgical-risk patients with symptomatic severe mitral valve regurgitation, MitraClip for transcatheter mitral valve repair and surgery showed similar survival rates in addition to superiority when compared to standard medical treatment. This...