A multicenter randomized study, (n = 573), that evaluated the role of aspirin in anticoagulated patients undergoing angioplasty. The primary endpoint was the rate of total bleeding, (TIMI), at 12 months follow-up. The administration of a dual therapy, (warfarin + clopidogrel), showed a significant reduction compared with the triple therapy, (19.5% vs. 44.9%, P &lt;0.001).<a href="https://solaci.org/en/2015/06/24/woest-randomized-trial-that-compared-dual-therapy-versus-triple-therapy-on-anticoagulated-patients/" title="Read more" >...</a>

Background: Octogenarian patients represent an increasingly growing population. In addition, this age group has a higher proportion of co-morbidities with more extensive and complex coronary disease. However, they have often been excluded from major studies, whose average age is usually 60 years. Despite having a more complex coronary anatomy, the role of pharmacological stent (DES)<a href="https://solaci.org/en/2015/06/24/xima-randomized-prospective-study-comparing-everolimus-eluting-stents-versus-conventional-stent-implantation-in-octogenarians/" title="Read more" >...</a>

Background: The ADAPT-DES registry showed a strong correlation between hypo-responders to clopidogrel and the likelihood of stent thrombosis at 30 days, while the impact of aspirin response has not been evaluated so far. This presentation focuses on the aspirin response impact in the clinical course of one year. Methods and Results: A total of 8,583<a href="https://solaci.org/en/2015/06/24/adapt-des-results-at-1-year-of-the-clinical-impact-of-hypo-responders-to-aspirin-and-clopidogrel/" title="Read more" >...</a>

Background: Contrast-induced nephropathy has been the subject of many studies not only because of the morbidity associated with prolonged hospital stay, (with dialysis requirement in some cases), but also with an increase in mortality in these patients. The preventive strategy hydration with saline solution 0.9% NaCl is the choice. However, the infusion rate and total<a href="https://solaci.org/en/2015/06/24/poseidon-study-a-prospective-randomized-single-center-study-comparing-a-sliding-scale-hydration-strategy-for-the-prevention-of-contrast-induced-nephropathy/" title="Read more" >...</a>

Fundamentals. Background: Although we&#8217;ve had more than a decade of experience with implanting drug-eluting stents, (DES), the best treatment for restenosis on these devices remains unknown. The drug-eluting balloons are a promising alternative which avoid the possibility of a new layer of metal on the restenotic injury. This study compared the performance of these balls<a href="https://solaci.org/en/2015/06/24/isar-desire-3-a-paclitaxel-eluting-balloon-versus-taxus-in-the-treatment-of-eluting-stent-restenosis/" title="Read more" >...</a>

Fundamentals: Previous studies have shown the benefits of a transradial approach in the context of coronary syndromes with ST-segment elevation. The aim of this study was to evaluate these benefits in AMI patients with ST-segment elevation within a window of up to 12 hours from the onset of symptoms. Methods: A randomized study conducted in<a href="https://solaci.org/en/2015/06/24/stemi-radial-a-prospective-randomized-trial-which-compares-radial-versus-femoral-access-in-patients-with-st-segment-elevation-acute-myocardial-infarction/" title="Read more" >...</a>

Introduction: The popliteal artery is a vessel considered unfavorable for the implantation of a stent due to the forces exerted in the popliteal fossa during limb flexion, which could fracture the stent antlers and compromise the outcome of the procedure at long-term. So far, stents used in popliteal lesions have not been compared with balloon<a href="https://solaci.org/en/2015/06/24/etap-endovascular-treatment-of-atherosclerotic-popliteal-artery-lesions-a-prospective-multi-center-randomized-study/" title="Read more" >...</a>

Foreword: The EPS MGUARD stent (embolic protection stent) has a fine metal structure covered by a thin polyethylene fiber mesh with pores of 5 microns wrapping the stent that might prevent distal embolization during primary angioplasty and would therefore be particularly attractive during primary angioplasty. Methods and Results: We included 432 patients referred for primary<a href="https://solaci.org/en/2015/06/24/master-trial-prospective-multicentre-randomized-trial-evaluating-the-mguard-stent-in-the-treatment-of-patients-with-acute-myocardial-infarction-with-st-segment-elevation-stemi/" title="Read more" >...</a>

This study randomized 120 patients with acute myocardial infarction after successful primary angioplasty with a residual ejection fraction (LVEF) &lt;45%. An intracoronary infusion with fixed doses of bone marrow derived stem cells vs. placebo was administered (randomization 2:1) 3 days after infarction vs. 7 (randomization 1:1). The objective was to assess ventricular and contractile function<a href="https://solaci.org/en/2015/06/24/time-use-and-duration-of-bone-marrow-derived-stem-cells-infusion-for-the-treatment-of-post-infarction-ventricular-dysfunction/" title="Read more" >...</a>

Given the individual variability of response to antiplatelet therapies, measuring platelet function and designing tailored therapies could be beneficial. The ARTIC study tested the superiority of bedside platelet function monitoring with drug adjustment vs. the conventional post DES therapy without monitoring and drug adjustment. It included 2466 patients with stable coronary disease or Non-ST Elevation<a href="https://solaci.org/en/2015/06/24/artic-study-bedside-platelet-function-monitoring-to-reduce-events-after-des-implantation/" title="Read more" >...</a>