Original title: Colchicine Treatment for the Prevention of Bare-Metal Stent Restenosis in Diabetic Patients. Reference: Spyridon Deftereos et al. J Am Coll Cardiol 2013;61:1679–85. In stent restenosis is more frequent in diabetic patients, who therefore find DES particularly beneficial. However, there is a subset of these patients with contraindication to prolonged double antiaggregation, due to a programmed surgery...
Original title: Moderate Procedural Sedation and Opioid Analgesia During Transradial Coronary Interventions to Prevent Spasm. A Prospective Randomized Study. Reference: Spyridon Deftereos et al. J Am Coll Cardiol Intv 2013;6:267–73. The trans-radial approach has become the preferred diagnostic and therapeutic study for evidence of minor vascular complications, shorter hospital stays, less blood loss and better outcomes in acute...
Original title: Moderate Procedural Sedation and Opioid Analgesia During Transradial Coronary Interventions to Prevent Spasm. A Prospective Randomized Study. Reference: Spyridon Deftereos et al. J Am Coll Cardiol Intv 2013;6:267–73. The trans-radial approach has become the preferred diagnostic and therapeutic study for evidence of minor vascular complications, shorter hospital stays, less blood loss and better outcomes in acute...
Original title: Transcatheter Aortic Valve Implantation With the Edwards SAPIEN Versus the Medtronic CoreValve Revalving System Devices. A Multicenter Collaborative Study: The PRAGMATIC Plus Initiative (Pooled-RotterdAm-Milano-Toulouse In Collaboration). Reference: Alaide Chieffo et al. J Am Coll Cardiol 2013;61:830–6. Since the introduction of percutaneous aortic valve replacement (TAVR), two devices have been widely used. For one side, the self-expanding...
Original title: Percutaneous Left Atrial Appendage Closure for Stroke Prophylaxis in Patients With Atrial Fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) Trial. Reference: Vivek Y. Reddy et al. Circulation. 2013;127:720-729. Atrial fibrillation is the most common sustained arrhythmia in the world and its importance lies...
Original title: Consensus document on the radial approach in percutaneous cardiovascular interventions: position paper by the European Association of Percutaneous Cardiovascular Interventions and Working Groups on Acute Cardiac Care and Thrombosis of the European Society of Cardiology. Reference: Martial Hamon et al. EuroIntervention 2013; 8-online publish-ahead-of-print January 2013. The European Society of Cardiology (ESC) recently published a consensus...
Original title: Trends in outcome after transfemoral transcatheter aortic valve implantation. Pooled-RotterdAm-Milano-Toulouse In Collaboration Plus (PRAGMATICPlus) initiative. Reference: Nicolas M. Van Mieghem et al. Am Heart J 2012;0:1-10. Article in press. Since its introduction in 2002, Transfemoral Transcatheter Aortic Valve Implantation (TAVI) has turned into a viable and safe strategy to treat patients with severe acute stenosis and...
Original title: Reduction in First and Recurrent Cardiovascular Events with Ticagrelor Compared with Clopidogrel in the PLATO Study. Reference: Payal Kohli et al. CIRCULATION AHA.112.124248. In analyzing randomized and monitored study outcomes, we usually observe that after the occurrence of any primary outcome event patients are typically blocked for further analysis. This practice limits the information on subsequent...
Original title: Assessment of Clinical Outcomes related to Early Discharge alter elective Percutaneous Coronary Intervention: COED PCI Reference: Purushothaman Muthusamy MD, et al. Catheterization and Cardiovascular Intervention 81:6-13 (2013) The standard procedure in most institutions is that after angioplasty (PTCA) patients are discharged the next morning. There are some reports in which they were ambulatory but the safety...
Original title: Association of Clopidogrel Pretreatment with mortality, Cardiovascular events, and Major Bleeding among patients undergoing percutaneous coronary intervention. A systematic review and Mata-analysis. Reference: Anne Bellemain-Appaix, MD et al. for the ACTION group. The loading of clopidogrel before coronary angioplasty is an accepted practice by most clinical and interventional cardiologists but, nevertheless, it is only based on...