Original Title: Biolimus A9 drug-coated stent vs. bare metal stent in patients presenting with ACS. A pre-specified LEADERS FREE ACS sub-study. Presenter: C.K. Naber. In ACS patients with high bleeding risk, guidelines recommend 3 to 6 months of dual ATP treatment for DES implantation or one month in case of conventional stenting. The...
Original Title: Revascularization in Patients with Multivessel Coronary Artery Disease and Severe Left Ventricular Systolic Dysfunction: Everolimus Eluting Stents vs Coronary Artery Bypass Graft Surgery Reference: Bangalore et al. Circulation. 2016 May 5. Epub ahead of print. Courtesy of Dr. Guillermo Migliaro. Guidelines recommend coronary artery bypass graft surgery (CABG) over percutaneous coronary...
Courtesy of Dr. Agustín Vecchia. There is no doubt cases of post out of hospital cardiac arrest (OHCA) secondary to an ST elevation acute coronary syndrome (STEMI) should be submitted to a coronary angiogram and eventually an angioplasty (PCI). However, in patients with non ST elevation MI, the use of a similar invasive strategy is...
Original Title: Clinical outcomes following “off-label” versus “established” indication of bioresorbable scaffolds for treatment of coronary artery disease in a real-world population. Reference: Tadashi Miyazaki, et al EuroIntervention 2016;11:475-478. Courtesy of Dr. Carlos Fava. Bioresorbable scaffolds (BSB) have shown their benefit in different studies, but there is little information available on “off label”...
Original Title: Optimal Strategy for Provisional Side Branch Intervention in Coronary Bifurcation Lesions. 3 – Year Outcomes of the SMART – STRATEGY Randomized Trial. Reference: Song YB et al. J Am Coll Cardiol Intv 2016;9:517-26. Courtesy of Dr. José A. G. Álvarez. The present publication is about the three year follow up outcomes of...
Original Title: CT Angiography for the Prediction of Hemodynamic Significance in Intermediate and Severe Lesions. Head-to-Head Comparison with Quantitative Coronary Angiography Using Fractional Flow Reserve as the Reference Standard. Reference: Matthew J. Budoff et al. J Am Coll Cardiol Img. 2016;9(5):559-564. The aim of this study was to compare the diagnostic accuracy of non-invasive...
Título original: Transulnar versus transradial access for coronary angiography or percutaneous coronary intervention: A meta-analysis of randomized controlled trials. Khagendra Dahal. Et al. Catheterization and cardiovascular Intervention 2016:87;857-865 Courtesy of Dr. Carlos Fava. Transradial access site (TRA) has been shown beneficial over the femoral (TFA), but there is little information on translunar access (TUA) that could...
The use of morphine in patients undergoing ST elevation acute coronary syndromes is associated to higher platelet reactivity and lower thrombolysiscapacity, according to this small study. The negative effects seem to resolve 2 days after administration. This transient effect is believed to be the result of the inhibition of the normal muscular activity of the...
EARLY-BAMI outcomes show the endovenous administration of metropol before primary PCI does not reduce infarct size. This double blind study randomized 683 STEMI patients within 12 hours of symptom onset to endovenous metropol (two 5 mg bolus, the first in the ambulance and the second before PCI) vs. placebo. Primary end point was infarct size...
This meta-analyzis of contemporary studies comparing the safety and efficacy of bivalirudin vs. heparin showed no differences in mortality between the two drugs and, consistently with other studies, bivalirudin was associated with an increased risk of acute stent thrombosis. During ACC 2015, the MATRIX study did succeed in showing global differences between the two drugs...