This study was designed to compare the apposition and neointimal coverage of struts by optical coherence tomography (OCT) of the new self-expanding sirolimus &nbsp;eluting stent (STENTYS SES) at 4 and 9 months in patients with STE-ACS. 152 patients randomized to STENTYS SES (n = 90) versus zotarolimus-eluting balloon-expandable stent (n = 62) were included. The<a href="https://solaci.org/en/2015/06/24/apposition-iv-self-expanding-des-in-acute-coronary-syndrome/" title="Read more" >...</a>

This study compared the clinical and angiographic results of the use of the provisional stent technique versus the 2 stents technique (TRYTON device at the side branch) in true bifurcations.&nbsp; The study with non-inferiority design, randomized 704 patients in total to drug-eluting stent in the main branch plus the TRYTON device in the side branch<a href="https://solaci.org/en/2015/06/24/tryton-dedicated-stent-for-bifurcations-not-inferior-than-the-provisional-technic/" title="Read more" >...</a>

This multicenter work from Japanrandomized 3200 patients to receive biodegradable polymer biolimus eluting stent(Nobori) or everolimus-eluting stent with permanent polymer (Xience / Promus). The primary end point for efficacy was any revascularizationlesion. A two year follow up the Nobori stent was non-inferior to death or myocardial infarction (7.83% versus 7.69%) and TLR (6.23% versus 5.95%).&nbsp;<a href="https://solaci.org/en/2015/06/24/next-trial-biodegradable-polymer-stent-nobori-was-similar-to-the-permanent-polymer-stents-xience-promus-at-2-years/" title="Read more" >...</a>

The use of drug-eluting stents versus bare metal stents is controversial in some clinical situations in patients at high risk of bleeding.This study randomized 1606 patients considered at low risk of restenosis but with high risk of bleeding receiving Zotarolimus eluting stent (Endeavor) or conventional stent.The clinical characteristics were similar between the two groups with<a href="https://solaci.org/en/2015/06/24/zeus-trial-patients-with-increased-risk-of-bleeding-may-benefit-from-eluting-stents-zotarolimus/" title="Read more" >...</a>

This randomized trial of a single center with consent obtained after randomization compared the use of bivalirudin versus heparin with the use of glycoprotein inhibitors arescue only in patients having ST segment elevation myocardial infarction.The primary efficacy endpoint was a composite of death, stroke, and myocardial revascularization of the target lesion and the primary safety<a href="https://solaci.org/en/2015/06/24/heat-ppci-bivalirudin-raises-major-cardiac-events-and-does-not-reduce-bleeding-the-most-controversial-and-criticized-study-at-the-acc-14/" title="Read more" >...</a>

Initial therapy for intermittent claudication has been historically the gear train, however, especially in recent years; the number of peripheral angioplasties has increased, proving highly effective for this condition. The aim of this study was to compare the clinical effectiveness of endovascular revascularization plus exercise versus exercise alone in patients with intermittent claudication. The study<a href="https://solaci.org/en/2015/06/24/erase-endovascular-treatment-plus-exercise-versus-exercise-alone-to-treat-claudication/" title="Read more" >...</a>

This randomized trial with an initial plan to include 1832 patients, compared stent implantation guided by fractional flow reserve (FFR) versus optimal medical treatment. In this study, we invasively evaluated the severity of lesion by FFR. Of this population, only patients who had lesions with significant translesional gradient (FFR &lt;0.9) were included in the study<a href="https://solaci.org/en/2015/06/24/fame-ii-this-randomized-trial-compared-a-stent-implantation-guided-by-fractional-flow-reserve-ffr-with-optimal-medical-treatment/" title="Read more" >...</a>

Randomized prospective study comparing the everolimus-eluting polymer-coated stent versus a biodegradable polymer with biolimus coated stent.&nbsp; While the use of first generation DES effectively reduces restenosis and reintervention rates, several meta-analyzes have shown a higher rate of late events of thrombotic origin associated with inflammatory phenomena and delayed reendothelialization at the site of implantation compared<a href="https://solaci.org/en/2015/06/24/compare-ii-a-randomized-prospective-study-compared-the-permanent-polymer-everolimus-eluting-stent-with-a-biodegradable-polymer-biolimus-coated-stent/" title="Read more" >...</a>

&nbsp;IABP-SHOCK II: Intra-aortic balloon use impact on 30-day mortality in patients with cardiogenic shock.&nbsp; Holger Thiele2012-08-26 Original title:&nbsp;IABP-SHOCK II: Randomized comparison of intraaortic balloon counterpulsation versus optimal medical therapy in addition to early revascularization in acute myocardial infarction complicated by cardiogenic shock

Review: Stable coronary disease remains a scenario where percutaneous coronary intervention, (PCI), has not cleared the edges. In a study conducted in 28 centers in Europe and the United States, a design model was created where all patients enrolled consecutively, (all comers trial in order to avoid selection bias), received an invasive functional assessment using<a href="https://solaci.org/en/2015/06/24/fame-ii-ischemia-guided-ig-percutaneous-coronary-intervention-pci-is-superior-to-medical-treatment/" title="Read more" >...</a>