Original title: The MASTER Trial – Prospective, Randomized, Multicenter Evaluation of a Polyethylene Terephthalate Micronet Mesh–Covered Stent (MGuard) in ST-Segment Elevation Myocardial Infarction. Reference: Gregg W. Stone et. al. J Am Coll Cardiol 2012; 60: 1975-1984 Primary angioplasty has proven effective in restoring epicardial flow but myocardial perfusion is often suboptimal. One of the main mechanisms is distal…
Bleeding risk in ACS. Do the scores we have work?
Original title: Comparing the predictive validity of three contemporary bleeding risk scores in acute coronary syndrome Reference: European Heart Journal: Acute Cardiovascular Care 2012 1: 222 DOI: 10.1177/2048872612453924 The aim of this study was to compare the validity of the three most widely used scores to predict the risk of bleeding in patients who are hospitalized for acute…
Predictors of invasive versus conservative treatment in elderly patients with acute coronary syndromes.
Original title: Predictors of Treatment in Acute Coronary Syndromes in the Elderly: Impact on Decision Making and Clinical Outcome After Interventional Versus Conservative Treatment. Reference: Harald Rittger et al. Catheterization and Cardiovascular Interventions 80:735–743 (2012). This study, recently published in Cath Cardiovasc Interven, was performed to determine the factors that helped physicians decide to be conservative or invasive.…
To discontinue clopidogrel after a year of infarction can be risky
Reference: Charlot et al. European Heart Journal 2012 (in press). International guideline recommendations approve giving dual antiplatelet therapy for a period of not less than 12 months after acute myocardial infarction. However, the benefit is unknown if the therapy is extended beyond 12 months. Perhaps its extension could be particularly useful in patients receiving pharmacological…
Renal failure in acute myocardial infarction
Reference: Fox y colaboradores. Short-term Outcomes of Acute Myocardial Infarction in Patients with Acute Kidney Injury: A Report from the National Cardiovascular Data Registry. Circulation 2012 (in press). The presence of chronic renal failure is common in patients referred for angioplasty. Its presence is associated with increased mortality and bleeding. However, the prevalence is unknown as…
Hyperglycemia on admission, an excess risk for infarction
Reference: Planer et al. International Journal of Cardiology 2012 (in press) Prognosis of patients enrolled in acute myocardial infarction with ST segment elevation (STEMI) has improved markedly, particularly as a result of reperfusion therapy. Despite these improvements, patients with diabetes mellitus (DM) are a high risk group in the short and long term compared with…
Unstable Angina
Reference: Jneid y colaboradores. JACC 2012 (inpress).
System Delays for STEMI patients linked to subsequent heart failure care
Reference: Terkelsen CJ, Jensen LO, Tilsted H-H, et al. Health care system delay and heart failure in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: Follow-up of population-based medical registry data. Ann Intern Med 2011; 155: 361-7. In patients with ST-segment myocardial infarction (STEMI), delays in obtaining primary percutaneous coronary intervention (PCI)…
Coronary CTA Use in Emergency Department saves time and money
Reference: Goldstein JA, Chinnaiyan KM, Abidov A, et al. The CT-STAT (coronary computed tomographic angiography for systemic triage of acute chest pain patients to treatment) trial. J Am Coll Cardiol 2011; 58: 1414-22. Using coronary computed tomographic angiography (CTA) as a screening tool for low-risk patients with chest pain in the emergency department achieves lower costs…
Ticagrelor vs. Clopidogrel in ST elevation MI: Pros and cons
Platelet Inhibition in the PLATO study: insights from the ECG substudy. En el Estudio PLATO quedó evidenciado que el Ticagrelor disminuyó la mortalidad a 12 meses en comparación con el Clopidogrel en el tratamiento de pacientes post-angioplastía por un síndrome coronario agudo o por un cuadro estable (4,5 vs. 5,9%; P<0.001). Estos resultados fueron del…
Tres Reglas para Identificar Infarto en la Guardia
Prioridad en la Evaluación Electrocardiográfica Inmediata en la Guardia: Validación de un Algoritmo En las actuales directrices internacionales se recomienda la inmediata realización ( Con el objeto de identificar los escenarios clínicos asociados a la presentación de un paciente con IAMST, un estudio epidemiológico recientemente publicado analizó todos los casos registrados durante el período 2007…