$Masa miocárdica fraccional para evaluar la severidad de la estenosis$

A New Indicator to Assess Stenosis Severity

This study looked at the role of fractional myocardial mass (vessel-specific myocardial mass) in the assessment of stenosis physiological severity.   Researchers used CT angiography to study this new concept of myocardial mass subtended by a specific vessel, which could reduce anatomical-physiological mismatch.   The study included 463 patients with 724 lesions evaluated by multislice<a href="https://solaci.org/en/2016/08/29/a-new-indicator-to-assess-stenosis-severity/" title="Read more" >...</a>

cangrelor vs. clopidogrel infartos peri-procedimiento

Peri-Procedural MI Reduction: Cangrelor or Clopidogrel?

Cangrelor is an intravenous P2Y12 inhibitor approved to reduce peri-procedural ischemic events in patients undergoing PCI that have not previously received any other P2Y12 inhibitor.   The CHAMPION PHOENIX trial randomized a total of 11,145 patients to cangrelor vs. clopidogrel.   The study sought to explore the effect of cangrelor on peri-procedural acute myocardial infarction<a href="https://solaci.org/en/2016/08/22/peri-procedural-mi-reduction-cangrelor-or-clopidogrel/" title="Read more" >...</a>

Optimal Duration of DAPT: How to Predict Long-Term Events

Courtesy of Dr. Santiago F. Coroleu.   Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel after percutaneous coronary intervention (PCI) reduces the risk for coronary thrombotic events (CTEs) at the expense of increasing risk for major bleeding (MB). However, the lack of information to accurately predict the occurrence of each event in out-of-hospital patients under<a href="https://solaci.org/en/2016/08/17/optimal-duration-of-dapt-how-to-predict-long-term-events/" title="Read more" >...</a>

Pre-TAVI Mitral Regurgitation Is Associated with Higher Mortality

Courtesy of Dr. Carlos Fava.   This study sought to analyze the clinical impact and the level of improvement of mitral regurgitation (MR) in patients who receive a transcatheter aortic valve replacement (TAVR), and to find potential candidates for double valve repair with percutaneous techniques.   Of 1.110 patients included, 177 (15.9%) suffered from severe pre-TAVR mitral<a href="https://solaci.org/en/2016/08/16/pre-tavi-mitral-regurgitation-is-associated-with-higher-mortality/" title="Read more" >...</a>

DES in primary PCI: The Best Option?

Courtesy of Dr. Brian Nazareth Donato.   The relative safety of drug-eluting stents (DES) and conventional bare-metal stents (BMS) in primary angioplasty (percutaneous coronary intervention, PCI) in patients with ST elevation myocardial infarction (STEMI) is still subject of debate.   A search was carried out using Medline, CENTRAL, EMBASE, TCTMD and Cardiosource. There were 9673 patients included,<a href="https://solaci.org/en/2016/08/10/des-in-primary-pci-the-best-option/" title="Read more" >...</a>

$celulas madre angina refractaria$

Stem Cells: A New Alternative for Refractory Angina?

Courtesy of Dr. Agustín Vecchia.   Recent investigations and certain randomized trials suggest that the administration of CD34+ stem cells to patients with refractory angina improves exercise tolerance and decreases angina frequency.   The following is a phase 3, randomized, double-blind multicenter trial comparing three groups of patients: active treatment through intramyocardial administration of CD34+ stem cells (autologous, purified), standard of care<a href="https://solaci.org/en/2016/08/10/stem-cells-a-new-alternative-for-refractory-angina/" title="Read more" >...</a>

BVS: Comparable to Second-Generation DES in Complex Lesions

A center carrying out a mid- to long-term follow-up of the performance of everolimus-eluting bioresorbable scaffolds (Absorb) observed that this new device has an acceptable rate of major cardiovascular events, when compared to second-generation drug-eluting stents. Furthermore, although the population was complex and non-selected, no cases of early thrombosis were reported. This study enrolled 249 patients<a href="https://solaci.org/en/2016/08/03/bvs-comparable-to-second-generation-des-in-complex-lesions/" title="Read more" >...</a>

Hugo Londero: “The arrival of interventional cardiology has changed many physicians’ personalities”.

He grew up in the 40s, surrounded by cap screws, dental crowns and damp from the Paraná River. His father, mother and two brothers, were dentists. Years later, his daughter and niece would also become dentists. But since his early years, Hugo Londero had known he would become a physician. He was certain his greatest<a href="https://solaci.org/en/2016/08/02/hugo-londero-the-arrival-of-interventional-cardiology-has-changed-many-physicians-personalities/" title="Read more" >...</a>

Non-Compliant Balloons Improve Bifurcation Outcomes

Courtesy of Dr. Carlos Fava. The provisional approach is the standard strategy to treat bifurcations, but it might cause dissection of the ostium, a serious complication of the side branch. The use of non-compliant balloons (NCB) ensures uniform, constant, and controlled expansion along balloon length, reducing the risk of dissection. The COBIS II registry enrolled<a href="https://solaci.org/en/2016/08/01/non-compliant-balloons-improve-bifurcation-outcomes/" title="Read more" >...</a>

Ticagrelor Reduces Events in Diabetics with Prior MI

    All studies on diabetics have shown these patients have higher risk rates of thrombotic events. This study sought to determine the optimal antiaggregation therapy with ticagrelor to prevent thrombotic events in diabetic patients with prior MI. The study analyzed diabetic patient and non-diabetic patient subgroups (n=6806 and n=14355, respectively) from the PEGASUS–TIMI 54<a href="https://solaci.org/en/2016/07/29/ticagrelor-reduces-events-in-diabetics-with-prior-mi/" title="Read more" >...</a>