The aim of this study was to compare the usefulness of primary angioplasty only to culprit vessel versus complete revascularization guided by fractional flow reserve (FFR) in patients admitted pursuing an acute myocardial infarction with ST-segment elevation and have multiple injuries vessels. After a successful primary angioplasty to culprit artery, patients were randomized 1:1 to...
The benefit of myocardial revascularization (angioplasty or surgery) guided by fractional flow reserve (FFR) in the context of acute coronary syndromes is poorly studied in the literature. The aim of this study was to compare myocardial revascularization guided by FFR versus Angiography in patients admitted suffering a non-ST segment elevation myocardial infarction. 350 patients were...
The aim of this study was to compare angioplasty guided by fractional flow reserve (FFR) versus conventional angiography in bifurcations treated with provisional stent technique for lateral branch. The study included patients with bifurcations 1,1,1 or 0,1,1 of Medina classification and lateral branches, superior to 2.5 mm. 2nd generation pharmacological stents were used. After stent...
Review: Stable coronary disease remains a scenario where percutaneous coronary intervention, (PCI), has not cleared the edges. In a study conducted in 28 centers in Europe and the United States, a design model was created where all patients enrolled consecutively, (all comers trial in order to avoid selection bias), received an invasive functional assessment using...
Several studies tested the utility of fractional flow reserve (FFR) to assess coronary lesions functionally. The FFR required for its measurement amaximum hyperemia that usually, is achieved with adenosine infusion. The “InstantaneousWave-freeRatio™” or iFR, has the advantage of not requiring maximum hyperemia.This prospective, multicenter, observational study that included 690 patients detectedthat iFR adequately classified 91.6%...
Original title: Randomized Comparison of FFR-Guided and Angiography-Guided Provisional Stenting of True Coronary Bifurcation Lesions The DKCRUSH-VI (Double Kissing Crush Versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions VI) Trial. Reference: Shao-Liang Chen et al. J Am Coll Cardiol Intv. 2015. Online before print. Angiography for guiding the need to implant a stent in the side...
Original title: FFR in the Transradial Era: Will Hand Vein Adenosine Infusion Suffice?A Comparative Study of the Extent, Rapidity, and Stability of Hyperemia From Hand and Femoral Venous Routes of Adenosine Administration. Reference: Peter Scott et al. J Am Coll Cardiol Intv. 2015, online before print. The aim of this study was to compare the administration of...
Original title: Prognostic Value of Fractional Flow Reserve Linking Physiologic Severity to Clinical Outcomes. Reference: Nils P. Johnson et al. J Am Coll Cardiol 2014;64:1641–54. Fractional flow reserve (FFR) has become an essential tool for guiding treatment, but its graded relationship to prognosis and its influence by medical treatment vs revascularization, remains unclear. The hypothesis of this study...
Original title: Atherosclerotic Plaque Characteristics by CT Angiography Identify Coronary Lesions That Cause IschemiaA Direct Comparison to Fractional Flow Reserve. Reference: Hyung-Bok Park et al. J Am CollCardiolImg. 2015;8(1):1-10. This trial evaluated the characteristics of arteriosclerotic plaques and its association with lesion ischemia by CT angiography (CTA) vs fractional flow reserve (FFR). FFR is the gold standard to...
Original title: The impact of age flow reserve-guided percutaneous coronary intervention: A FAME (Fractional Flow Reserve versus Angiography for Multivessel Evaluation) trial substudy. Reference: Hong-Seok Lim et al. International Journal of Cardiology 2014; 177:66-70 The FAME study has shown the benefit of FFR guided PCI, but the question as to whether age affects lesion evaluation remains unclear. A...