Original Title: Early Intravenous Beta-Blockers in Patients with ST-Segment Elevation Myocardial Infarction before Primary Percutaneous Coronary Intervention. Reference: Roolvink V et al. J Am Coll Cardiol. 2016 Jun 14;67(23):2705-15. The impact of endovenous beta-blockers before primary PCI has not been established yet. This is the first double blind multicenter trial, controlled with placebo, to...
Original Title: Utilizing Post-Intervention Fractional Flow Reserve to Optimize Acute Results and the Relationship to Long-Term Outcomes Reference: Shiv K. Agarwal et al. J Am Coll Cardiol Intv. 2016;9(10):1022-1031. Courtesy of Dr. Agustín Vecchia. At present, fractional flow reserve (FFR) has become the gold standard to define ischemia in intermediate lesions, and to...
Original Title: Angiographic and Clinical Outcomes After Everolimus-Eluting Stenting for Unprotected Left Main Disease and High Anatomic Coronary Complexity. Reference: JACC Cardiovascular Interventions. Doi: 10.1016/j.jcin.2016.02.016. Courtesy of Dr. Agustín Vecchia. In patients with unprotected left main disease (ULMD) associated to complex coronary anatomy, choosing a revascularization strategy can be challenging. Current guidelines recommend surgery for...
Original Title: iFR/FFR and IVUS-guided percutaneous coronary revascularization with new-generation DES in patients with de novo three-vessel disease: 30-day outcomes of the SYNTAX II trial. Presenter: P. W. Serruys. The European Society of Cardiology guidelines recommend PCI for patients with multivessel disease and a Syntax score. A prospective, multicenter, single arm study was carried...
Original Title: Sealing intermediate non-obstructive coronary SVG lesions with DES as a new approach to maintaining vein graft patency and reducing cardiac events: the VELETI II randomized clinical trial. Presenter: J. Rodes Cabal. Non-obstructive SVG lesions affect mid-term prognosis negatively. There is little evidence on the safety and efficacy of non-obstructive intermediate SVG lesions...
Original Title: Upper extremity function post-transradial (TR)-PCI: interim results. Presenter: Eva Zwaan. The use of transradial access has increased in the clinical practice thanks to the reduction of vascular and bleeding complications in addition to the shorter time of hospitalization. The aim of this study was to assess prevalence, magnitude and mechanisms responsible...
Original Title: Optical frequency domain imaging vs. IVUS in PCI: the OPINION trial – one-year primary endpoint results. Presenter: T. Kubo. Optical coherence tomography (OCT) is increasingly being used in the daily practice given its greater capacity to define anatomical structures vs. intravascular ultrasound (IVUS). The clinical impact of this decision remains unclear. ...
Original Title: Meta-analysis of the long-term effect of routine aspiration thrombectomy in patients undergoing primary percutaneous coronary intervention. Reference: Mancini JG et al. Am J Cardiol. 2016; Epub ahead of print. A large meta-analyzis confirms routine aspiration thrombectomy in the context of primary PCI has no clinical benefit and could increase the risk of...
Original Title: Effects of Age and Sex on Clinical Outcomes after Percutaneous Coronary Intervention Relative to Coronary Artery Bypass Grafting in Patients with Triple Vessel Coronary Artery Disease. Reference: KyoheiYamaji et al. Circulation. 2016 Mar 23. [Epub ahead of print]. Sex and age are factors that are often considered in the daily practice to decide...
Both ischemic postconditioning and deferred stenting showed no benefit in randomized studies conducted as part of the DANAMI 3 program. Both the DANAMI 3-DEFER and the DANAMI 3-iPOSTshowed slight improvements in ventricular function after intervention, but clinical end points saw no change. This does not mean that outcomes should be considered negative, only that the...