Courtesy of Dr. Carlos Fava. It has been proved that in a setting of acute myocardial infarction with multivessel lesions, only the culprit vessel must be treated (if there is no hemodynamic compromise) at first, and other severe lesions are to be treated during a second session. However, proper conduct in cases with presence of chronic...
Original Title: Ventricular Assist Device in Acute Myocardial Infarction. Reference: Deepak Acharya et al. J Am Coll Cardiol. 2016;67(16):1871-1880. Patients undergoing acute myocardial infarction (AMI) with acute cardiac failure or cardiogenic shock have a high mortality rate with the conventional treatment. This study assessed the outcomes of patients with AMI receiving a durable ventricular assist...
A bioabsorbable platform implant in the context of ST segment elevation acute myocardial infarction is feasible although the subsequent cicatrization of the artery is not documented. The objective of this work was to evaluate optical coherence tomography (OCT) in patients who received everolimus-releasing bioabsorbable platform in the context of primary angioplasty. A total of 39...
Dr. David Antoniucci presented the immediate results of randomized trial SMART SMART (n=80, 1:1) comparing manual thrombectomy (MAT) vs. rheolytic aspiration (RT) in the context of ST elevation acute myocardial infarction (≤6 hours). In this study, primary outcome was residual thrombus burden after aspiration assessed with optical coherence tomography (OCT). Thrombus burden was defined as...
Fundamentals: Previous studies have shown the benefits of a transradial approach in the context of coronary syndromes with ST-segment elevation. The aim of this study was to evaluate these benefits in AMI patients with ST-segment elevation within a window of up to 12 hours from the onset of symptoms. Methods: A randomized study conducted in...
Foreword: The EPS MGUARD stent (embolic protection stent) has a fine metal structure covered by a thin polyethylene fiber mesh with pores of 5 microns wrapping the stent that might prevent distal embolization during primary angioplasty and would therefore be particularly attractive during primary angioplasty. Methods and Results: We included 432 patients referred for primary...
Background: To evaluate whether the administration of eplerenone 24 hours after an acute myocardial infarction (AMI) in patients without heart failure reduces mortality and cardiovascular morbidity. Methods and results: The study randomized 612 patients to evaluate the safety and efficacy of early treatment with eplerenone in patients with AMI. The primary end point was a...
Background: To evaluate whether the administration of eplerenone 24 hours after an acute myocardial infarction (AMI) in patients without heart failure reduces mortality and cardiovascular morbidity. Methods and results: The study randomized 612 patients to evaluate the safety and efficacy of early treatment with eplerenone in patients with AMI. The primary end point was a...
The acute chest pain is responsible for more than 11 % of queries to an emergency service . Only 10% of these patients really have an acute myocardial infarction. The standard protocol for managing these patients includes serial electrocardiogram, dosage of biomarkers and an observation time of 6-12 hours. This overloads the emergency services and...
Original title: Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. PEGASUS-TIMI 54. Referencia: Marc P. Bonaca et al. N Engl J Med. 2015 Mar 14. Patients with acute myocardial infarction (AMI) have an increased risk of recurrent events suggesting that this population could benefit from intensive secondary prevention. Current guidelines recommend adding to aspirin an...