180 patients with colchicine 0.5 mg twice daily from 48-72 hs. before surgery versus 180 patients to placebo were randomized. The medication was continued for a month. The aim of the study was to evaluate whether colchicine was able to avoid the post-pericardiotomy syndrome.  The post pericardiotomy syndrome occurred in 19.4% of patients in the...

The new generation drug-eluting everolimus or biolimus stents have proved superior to the first generation. However, neo intimal proliferation and late thrombosis remains a problem not yet solved same for all drug-eluting stents. The Absorb (Abbott Vascular, Abbott Park, IL, USA) is the first absorbable vascular support approved for clinical use. The EVERBIO II study...

The current recommendation for dual anti-aggregation post-DES implantation is 12 months. However, the ideal length for specific types of stents is unclear. This study aimed to evaluate the clinical non-inferiority at 3 months versus 12 months of dual anti-platelet therapy in patients undergoing coronary angioplasty with zotarolimus-eluting stents. The study randomized 1:1 to 3 months...

There is no strong evidence in the literature that the polymer type isolated (permanent or degradable) influences clinical outcomes after angioplasty and if the time of double anti-aggregation should be different with the degradable polymer. This work, with non-inferiority design, aimed to compare the sirolimus-eluting biodegradable polymer stent (Tivoli) versus the permanent polymer sirolimus-eluting stent...

Mild refractory hypertension patients were defined as those with daytime systolic BP 135-149 and diastolic BP 90-94 mmHg in ambulatory monitoring. They were randomized to renal denervation (n = 35) versus control invasive procedure (n = 36). The primary end point was the change in systolic pressure of 24 hours ambulatory monitoring at 6 months....

It is hypothesized that the presence of a right-left shunt can trigger migraine attacks. The aim of this study was to evaluate whether the closure of a patent foramen ovale may help treat patients with migraine with aura refractory to treatment. A total of 107 patients were included; 53 in the group of foramen ovale...

There are a significant number of patients receiving drug-eluting stents and besides, require oral anticoagulation. The combination of anticoagulants, aspirin, and clopidogrel greatly increases the rate of bleeding, because of this, the time of the triple scheme should be as short as possible.  The aim of this study was to compare the triple therapy for...

TRYTON is a cobalt chromium device specifically dedicated for bifurcation lesions to be implanted in the side branch. Circumflex artery is the major lateral branch fund the coronary tree. Between 2008 and 2011 this work included 52 patients with left main coronary unprotected lesions who underwent angioplasty with drug-eluting stent in the coronary trunk left...

This record has been created in order to evaluate the results of percutaneous aortic valve replacement in the UK and currently includes more than 4500 patients with 100% follow-up for mortality. The 3-year mortality was 61.6 % beyond the device or path. Atrial fibrillation, renal failure, chronic obstructive pulmonary disease and a EuroSCORE > 18.5...

Previous studies suggest the excellent performance of the bioactive coated stent TITAN 2 compared with drug-eluting stents (DES). The aim of the study was to evaluate the results of this device in patients undergoing both ST segment elevation and without ST segment elevation acute coronary syndrome. A total of 1066 patients were included, of whom...