Article The goal of this study was to assess the efficacy of low doses of aspirin (AAS) for primary prevention of cardiovascular events in Japanese elderly patients with multiple risk factors for arteriosclerosis but with no history of heart disease. This open study included patients between 60 and 85 with risk factors such as high...
FACTOR 64: Routine coronary CT angiography in patients at high risk for heart disease.
Article 900 patients with asymptomatic diabetes mellitus were randomized to CT angiography vs. Standard management. Primary end point was a combination of death, infarction and unstable angina. 63% of patients randomized to CT angiography presented some degree of heart disease and 4.7% presented severe lesions. This resulted in more coronary interventions, more use of statins...
PRIMA: Closure of patent foramen ovale in patients with migraine with aura refractory
It is hypothesized that the presence of a right-left shunt can trigger migraine attacks. The aim of this study was to evaluate whether the closure of a patent foramen ovale may help treat patients with migraine with aura refractory to treatment. A total of 107 patients were included; 53 in the group of foramen ovale...
CTO-IVUS: IVUS clinical impact in total occlusions with 2nd generation DES
While the use of intravascular ultrasound (IVUS) during coronary intervention proved useful in multiple studies, there is limited evidence in the literature regarding its use in specifically in chronic total occlusions. The IVUS may help guide in recognizing the true lumen and better distal positioning, better coverage of stent, an optimal apposition and expansion, diagnose...
ORBIT II: atherectomy for heavily calcified lesions
The aim of this study was to evaluate the safety and efficacy of coronary orbital atherectomy system Diamondback to prepare de novo lesions severely calcified to stent implantation. This orbital atherectomy system is the first approved by the FDA to treat this type of injury, so the study had no control group. The rate of...
Clinical Indications of CTO recanalization
Quesada, Ramón (USA)2014-04-24
TOPCAT: Spironolactone in heart failure with preserved ejection fraction
The aldosterone blockade has shown benefit in the treatment of heart failure with systolic dysfunction after stroke. The aim of this study was to evaluate the effect of spironolactone in patients with preserved ejection fraction. This was a multicenter, randomized study that included 1722 patients in the spironolactone group and 1723 in the placebo group....
SMART: Manual Thrombectomy vs. Rheolytic Aspiration in ST-segment Elevation Acute Myocardial Infarction.
Dr. David Antoniucci presented the immediate results of randomized trial SMART SMART (n=80, 1:1) comparing manual thrombectomy (MAT) vs. rheolytic aspiration (RT) in the context of ST elevation acute myocardial infarction (≤6 hours). In this study, primary outcome was residual thrombus burden after aspiration assessed with optical coherence tomography (OCT). Thrombus burden was defined as...
Estudio STAMPEDE: La cirugía bariátrica demostró beneficio metabólico comparado con el tratamiento medico optimo en el control de factores de riesgo cardiovascular en diabéticos tipo II obesos.
Read article Editorial Philip Raymond Schauer.2012-03-25