According to the European Society of Cardiology (ESC Guidelines 2021) an early invasive strategy is recommended (<24h) for high-risk patients with acute coronary syndrome with no ST elevation (NSTE-ACS), namely patients presenting a rise or fall in cardiac troponin, dynamic ST- or T-wave changes and GRACE risk score >140. Early intervention (<2h) is reserved for<a href="https://solaci.org/en/2022/06/09/when-is-the-ideal-timing-for-nste-acs-percutaneous-intervention/" title="Read more" >...</a>
Revascularization Using DES in Infrapopliteal Disease: Meta-Analysis and Change of Paradigm?
Peripheral vascular disease (PVD) has been under-studied and under-recognized in comparison with ischemic heart disease and stroke, despite its well-known impact on quality of life and its associated morbidity and mortality. According to a systematic review, it was estimated that in 2015 about 238 million people globally had PVD. This number is on the rise.<a href="https://solaci.org/en/2022/06/01/revascularization-using-des-in-infrapopliteal-disease-meta-analysis-and-change-of-paradigm/" title="Read more" >...</a>
Coronary Angioplasty Evolution According to Syntax II: 5-Year Followup
It has been long since the SYNTAX (NEJM 2009) came out comparing percutaneous coronary intervention (PCI) against coronary artery bypass grafting (CABG). That emblematic study associated PCI with first generation drug eluting stents (Taxus) with increased major cardiac and cerebrovascular events (all-cause mortality, AMI, stroke, or any revascularization – MACCE) vs. CABG, at 5 years,<a href="https://solaci.org/en/2022/05/05/coronary-angioplasty-evolution-according-to-syntax-ii-5-year-followup/" title="Read more" >...</a>
IVUS-Guided Coronary Angioplasty: Promising Results at 3-Year Follow-Up
Intravascular ultrasound (IVUS) to guide drug-eluting stent (DES) implantation has been evaluated in several studies. Two randomized studies, IVUS-XPL (Impact of Intravascular Ultrasound Guidance on the Outcomes of Xience Prime Stents in Long Lesions) and ULTIMATE (Intravascular Ultrasound Guided Drug Eluting Stents Implantation in All-Comers Coronary Lesions), have shown fewer repeat revascularizations compared with angiography-guided<a href="https://solaci.org/en/2022/05/02/ivus-guided-coronary-angioplasty-promising-results-at-3-year-follow-up/" title="Read more" >...</a>
Should We Start Stenting with DES in Femoropopliteal Territory?
Percutaneous intervention of femoropopliteal lesions have been the standard strategy these past two decades. The development of drug eluting stents (DES) or drug eluting balloons (DEB) has improved patency rate compared against conventional balloon angioplasty. The ILLUMINA -a multicenter study- looked into the polymer free self-expanding stent NiTiDES, which showed at 1 year an 87%<a href="https://solaci.org/en/2022/04/07/should-we-start-stenting-with-des-in-femoropopliteal-territory/" title="Read more" >...</a>
IVUS in Femoropopliteal PCI: Should We Start Using It?
For approximately two decades now, PCI has been the treatment of choice in femoropopliteal territory, and even though technological developments and increasing operator experience have indeed improved outcomes, IVUS (which has showed great benefits in PCI, even reducing left main mortality) is hardly used in this territory. This was a prospective randomized controlled study including<a href="https://solaci.org/en/2022/03/29/ivus-in-femoropopliteal-pci-should-we-start-using-it/" title="Read more" >...</a>
Wire Jailing at Side Branch to Prevent Occlusion After Main Vessel Stenting: Should It Be the Standard of Care?
While the ideal treatment for coronary bifurcation is provisional stenting, this can be associated with side branch occlusion, which leads to severe adverse events. To prevent this complication, several treatments have been proposed. One of them is wire jailing at side branch before stent implantation in the main vessel. However, the actual benefit of this<a href="https://solaci.org/en/2022/03/29/wire-jailing-at-side-branch-to-prevent-occlusion-after-main-vessel-stenting-should-it-be-the-standard-of-care/" title="Read more" >...</a>
REVERSE-IT | Bentracimab: Progress on the Antidote for Ticagrelor in Emergency Scenarios
Optimizing an antiplatelet therapy after an acute coronary syndrome (ACS) aims at reducing the major adverse cardiac events (MACE) caused by atherosclerotic disease. Ticagrelor is a potent P2Y12 inhibitor that directly prevents platelet activation. It is characterized by a rapid and consistent onset of action throughout its administration (twice daily) and its proven pleiotropic effects,<a href="https://solaci.org/en/2022/03/25/reverse-it-bentracimab-progress-on-the-antidote-for-ticagrelor-in-emergency-scenarios/" title="Read more" >...</a>
Sorrow for the Loss of Dr. Sousa
On behalf of the Latin American Society of Interventional Cardiology (SOLACI), We extend our deepest condolences for the departure of our esteemed professor Doctor José Eduardo Morais Rego Sousa, renowned hemodynamist and interventional cardiologist, former Director of the Institute of Cardiology Dante Pazzanese, the Brazilian Society of Interventional Cardiology (SBHCI) and a pillar in the<a href="https://solaci.org/en/2022/03/16/sorrow-for-the-loss-of-dr-sousa/" title="Read more" >...</a>
IVUS in Acute Coronary Syndrome: A New Requirement?
The use of intravascular ultrasound (IVUS) has seen exponential growth across registries over the years, combined with mounting and increasingly robust evidence. The fact that it will enable us to characterize plaque morphology and extension prior the intervention, and even assess stent expansion post intervention, has turned it into a pillar of our efforts to<a href="https://solaci.org/en/2022/03/07/ivus-in-acute-coronary-syndrome-a-new-requirement/" title="Read more" >...</a>