According to the EXCEL trial, peri-procedural infarction was more common after left main coronary artery surgery compared with angioplasty, and it was strongly associated with increased 3-year mortality after controlling all possible confounding variables. This increased mortality was only present in extensive infarctions with an increase in CK-MB ≥10×. The EXCEL trial seems to want<a href="https://solaci.org/en/2019/07/05/peri-procedural-infarction-in-angioplasty-vs-surgery-in-the-left-main-coronary-artery/" title="Read more" >...</a>
What Happens When We Are Blinded by Left Main Disease and Ignore All Other Lesions?
According to this recent Excel analysis, mortality seems to rise when the SYNTAX II score is not taken into account when defining the revascularization strategy. The difference does not reach statistical significance and further studies are required, but the message is clear: the left main coronary artery is not the only thing that matters; other<a href="https://solaci.org/en/2019/06/24/what-happens-when-we-are-blinded-by-left-main-disease-and-ignore-all-other-lesions/" title="Read more" >...</a>
Radial Access Is Always Preferred, Even for Treatment of the Left Main Coronary Artery
The potential need for a 7-Fr guidewire, the use of several coronary guidewires and/or a kissing balloon, and the requirement of indispensable monitoring by intravascular ultrasound (IVUS) have been used by some interventional cardiologists as excuses to resist radial access. In that sense, left main coronary artery angioplasty was the last stand of femoral access.<a href="https://solaci.org/en/2019/01/04/radial-access-is-always-preferred-even-for-treatment-of-the-left-main-coronary-artery/" title="Read more" >...</a>
TCT 2018 | MAIN COMPARE: Angioplasty vs. Surgery for Left Main Coronary Artery Disease at 10 Years
Several studies (some of them recent, some of them not so much so) have compared left main coronary artery angioplasty and myocardial revascularization surgery. Combined, these works compose a large corpus of evidence, but follow-up has not gone beyond 5 years in any case. The main aim of this study (presented at TCT 2018 and published simultaneously<a href="https://solaci.org/en/2018/10/08/tct-2018-main-compare-angioplasty-vs-surgery-for-left-main-coronary-artery-disease-at-10-years/" title="Read more" >...</a>
EXCEL Sub-Study: The Site of the Left Main Coronary Artery Lesion Does Not Alter History
The EXCEL study, originally presented at TCT 2016 and published simultaneously in the New England Journal of Medicine (NEJM), showed that angioplasty and surgery in patients with left main coronary artery disease have similar rates of mortality, infarction, and stroke at 3 years. This sub-study, recently published in J Am Coll Cardiol Intv, adds that the<a href="https://solaci.org/en/2018/07/17/excel-sub-study-the-site-of-the-left-main-coronary-artery-lesion-does-not-alter-history/" title="Read more" >...</a>
Should Sex Be Taken into Account with Left Main Coronary Artery Revascularization?
The EXCEL trial did not find the sex of patients with left main coronary artery disease to be an independent predictor of adverse events after revascularization. However, women who underwent angioplasty had a trend towards worse outcomes, a finding that might be related to comorbidities and somewhat increased chances of peri-procedural complications. In its formal<a href="https://solaci.org/en/2018/07/10/should-sex-be-taken-into-account-with-left-main-coronary-artery-revascularization/" title="Read more" >...</a>
EuroPCR 2018 | SYNTAX III REVOLUTION: Excellent Correlation Between Angiography and Computerized Tomography in Patients with Left Main and Multivessel Disease
In patients with left main or three-vessel coronary disease, heart team decisions on revascularization strategy (angioplasty or surgery) may be made based solely on noninvasive computerized tomography (CT) angiography, since there is great correlation between its results and those determined by conventional angiography. For the SYNTAX III REVOLUTION study, Dr. Serruys and his colleagues randomized<a href="https://solaci.org/en/2018/05/24/europcr-2018-syntax-iii-revolution-excellent-correlation-between-angiography-and-computerized-tomography-in-patients-with-left-main-and-multivessel-disease/" title="Read more" >...</a>
DES XL for Left Main Coronary Artery Lesions
DES XL for Left Main Coronary Artery Lesions. Presenters: Dr. Carlos Calderas, Venezuela. Dr. Alejandro Ricalde, México. This video, sponsored and funded by Medtronic, was filmed during SOLACI-CACI 2017 Congress, at Hilton Buenos Aires Hotel (in Argentina). Do you want to take a look at all other SOLACI-CACI 2017 Congress Medtronic cases? Watch them We are interested in your<a href="https://solaci.org/en/2018/01/12/des-xl-for-left-main-coronary-artery-lesions/" title="Read more" >...</a>
Current Perspectives on the Left Main Coronary Artery
Current Perspectives on the Left Main Coronary Artery. Presenters: Dr. Oscar Méndiz, Argentina. Dr. Fernando Cura, Argentina. Dr. Ricardo Lluberas, Uruguay. This video, sponsored and funded by Medtronic, was filmed during SOLACI-CACI 2017 Congress, at Hilton Buenos Aires Hotel (in Argentina). Do you want to take a look at all other SOLACI-CACI 2017 Congress Medtronic cases? Watch them We<a href="https://solaci.org/en/2018/01/12/current-perspectives-on-the-left-main-coronary-artery/" title="Read more" >...</a>
Quality of Life Between Surgery and Angioplasty for the Treatment of Left Main Disease
In recent years, angioplasty with drug-eluting stents (DES) has emerged as an alternative to myocardial revascularization surgery in patients with left main coronary artery disease. Both European and American guidelines offer a Class IIa recommendation for left main coronary artery (LMCA) angioplasty in selected patients. The EXCEL (Evaluation of Xience Versus Coronary Artery Bypass Surgery for<a href="https://solaci.org/en/2018/01/11/quality-of-life-between-surgery-and-angioplasty-for-the-treatment-of-left-main-disease/" title="Read more" >...</a>