Difference in mortality with surgery versus angioplasty in diabetic multivessel patients

Original title: Comparison of coronary artery bypass surgery and percutaneous coronary intervention in patients with diabetes: A meta-analysis of randomized controlled trials. Reference: Verma S. et al. Lancet Diabetes Endocrinol. 2013;Epub ahead of print. The FREEDOM study was the last of the randomized studies that compared the results of surgery versus coronary angioplasty in diabetic multivessel patients showing a<a href="https://solaci.org/en/2013/09/18/n-3620/" title="Read more" >...</a>

Primary angioplasty , a race against time

Original title: Door-to-Balloon Time and Mortality among Patients Undergoing Primary PCI. Reference: Daniel S. Menees et al. N Engl J Med 2013;369:901-9. For more than a decade has been ranked , like a race, to the delay times that occur in hospitals until angioplasty is performed in the context of an infarct with ST segment elevation . Several<a href="https://solaci.org/en/2013/09/13/n-3606/" title="Read more" >...</a>

Ticagrelor reduces in-stent thrombosis in patients with acute coronary syndromes

Original title: Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: An analysis from the prospective randomized PLATO trial. Reference: Steg PG et al. Circulation. 2013; Epub ahead of print The PLATO study randomized 18624 patients with acute coronary syndrome to receive ticagrelor   (180 mg loading dose followed by 90 mg twice daily )<a href="https://solaci.org/en/2013/09/12/n-3599/" title="Read more" >...</a>

Low flow impact on outcomes following TAVI should be taken into account

Original title: Impact of Low Flow on the Outcome of High-Risk Patients Undergoing Transcatheter Aortic Valve Replacement. Reference: Florent Le Ven, et al. J Am Coll Cardiol 62;9:792-788 A study of low flow (SVi <35ml/m2) in the context of severe aortic stenosis has shown it is a predictor of worse outcomes after surgery, even though evolution with medical<a href="https://solaci.org/en/2013/08/26/n-3550/" title="Read more" >...</a>

Stent Thrombosis in the Real World

Original title: Incidence and predictors of stent trombosis: a single-centre study of 5833 consecutive patients undergoing coronary artery stenting Reference: Javaid Iqbal et al. EuroInterventional 2013;9:62-69 Though potentially fatal, stent thrombosis is a low frequency event associated to stent malapposition, fractures, resistance to antiplatelet therapies, and diseases such as diabetes and kidney disease, among other factors. 5883 pacients<a href="https://solaci.org/en/2013/05/31/n-2773/" title="Read more" >...</a>

Incomplete revascularization: no longer a binary variable

Original title: Residual SYNTAX score after PCI for triple vessel coronary artery disease: quantifying the adverse effect of incomplete revascularisation. Reference: Christopher J. Malkin et al. EuroIntervention 2013;8:1286-1295. In the angioplasty branch of the SYNTAX study, complete revascularization was reached in 56.7% of the population. On the other hand, in the real world, around 40% of patients that<a href="https://solaci.org/en/2013/04/05/n-2822/" title="Read more" >...</a>

Appendage trans-catheter closure is equivalent to anticoagulation in fibrillated patients.

Original title: Percutaneous Left Atrial Appendage Closure for Stroke Prophylaxis in Patients With Atrial Fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) Trial. Reference: Vivek Y. Reddy et al. Circulation. 2013;127:720-729. Atrial fibrillation is the most common sustained arrhythmia in the world and its importance lies<a href="https://solaci.org/en/2013/03/01/n-2927/" title="Read more" >...</a>

Renal denervation at one year, the benefit remains.

Original title: Renal Sympathetic Denervation for Treatment of Drug-Resistant Hypertension Clinical Perspective Reference: Murray D. Ester et al. Circulation 2012; 126: 2976-2982 Renal sympathetic activation contributes to the pathogenesis of hypertension. The Symplicity HTN – 2 was a multicenter, randomized study which demonstrated that renal denervation produced a significant decrease in blood pressure at 6 months in patients<a href="https://solaci.org/en/2013/01/18/n-3214/" title="Read more" >...</a>

MRI different injuries post carotid angioplasty versus endarterectomy.

Original title: Characteristics of Ischemic Brain Lesions After Stenting or Endarterectomy for Symptomatic Carotid Artery Stenosis : Results From the International Carotid Stenting Study-Magnetic Resonance Imaging Substudy (ICSS-MRI). Reference: Henrik Gensicke et al. Stroke 2013;44:80-86. This work is a sub-study using magnetic resonance imaging (MRI) of the International Carotid Stenting Study (ICSS) that randomized carotid angioplasty (CAS) or<a href="https://solaci.org/en/2013/01/17/n-3207/" title="Read more" >...</a>

Diabetics with multivessel, must keep waiting.

Original title: Strategies for Multivessel Revascularization in Patients with Diabetes. The FREEDOM Trial. Reference: Michael E. Farkouh et al. N Engl J Med 2012. DOI: 10.1056/NEJMoa1211585 This study was designed to determine the best revascularization strategy in diabetic patients with multivessel using current techniques of angioplasty (PCI) and surgery (CABG). Randomized 1:1 diabetic patients with injuries > 70%<a href="https://solaci.org/en/2012/11/08/n-3732/" title="Read more" >...</a>