acute myocardial infarction

PCI with everolimus eluting stent or CABG for multivessel coronary artery disease.

Original title:&nbsp;Everolimus-Eluting Stents or Bypass Surgery for Multivessel Coronary Disease.&nbsp;Reference:&nbsp;Sripal Bangalore, M.D. et al. N Engl J Med. 2015 Mar 26;372(13):1213-22. Coronary artery bypass grafting (CABG) have had better outcomes than percutaneous coronary intervention (PCI) in the treatment of multivessel coronary disease. &nbsp;However, this information comes from studies that do not include new generation stents.<a href="https://solaci.org/en/2015/04/09/pci-with-everolimus-eluting-stent-or-cabg-for-multivessel-coronary-artery-disease/" title="Read more" >...</a>

Zotarolimus eluting stent with one month of dual antiplatelet therapy

Original title:&nbsp;Zotarolimus-Eluting Versus Bare-Metal Stents in Uncertain Drug-Eluting Stent Candidates.&nbsp;Reference:&nbsp;Marco Valgimigli et al. J Am Coll Cardiol. 2015;65(8):805-815. The use of drug eluting stents (DES) in patients at high risk of bleeding or thrombosis has not been studied prospectively. Data on patients at high risk of bleeding and low restenosis are limited. This study compared<a href="https://solaci.org/en/2015/02/25/zotarolimus-eluting-stent-with-one-month-of-dual-antiplatelet-therapy/" title="Read more" >...</a>

Net clinical benefit of bivalirudin in STEMI patients

Original title:&nbsp;Bivalirudin Versus Heparin With or Without Glycoprotein IIb/IIIa Inhibitors in Patients With STEMI Undergoing Primary Percutaneous Coronary Intervention: Pooled Patient-Level Analysis From the HORIZONS-AMI and EUROMAX Trials.&nbsp;Reference:&nbsp;Stone GW et al. J Am CollCardiol. 2015 Jan 6;65(1):27-38. The HORIZONS-AMI (Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction) that included 3602 STEMI patients undergoing<a href="https://solaci.org/en/2015/01/29/net-clinical-benefit-of-bivalirudin-in-stemi-patients/" title="Read more" >...</a>

Never ending controversy over the duration of post DES dual antiplatelet therapy

Original title:&nbsp;Second Generation Drug-Eluting Stents Implantation Followed by Six Versus Twelve-Month &#8211; Dual Antiplatelet Therapy- The SECURITY Randomized Clinical Trial.&nbsp;Reference:&nbsp;Antonio Colombo et al. J Am CollCardiol. 2014 Nov 18;64(20):2086-97. The optimal duration of dual antiplatelet therapy after second-generation DES implantation is still debated and apparently will remain controversial for some time. The aim of this<a href="https://solaci.org/en/2015/01/15/never-ending-controversy-over-the-duration-of-post-des-dual-antiplatelet-therapy/" title="Read more" >...</a>

Enoxaparin appears superior to unfractionated heparin in patients undergoing primary angioplasty

Original title:&nbsp;A direct comparison of intravenous enoxaparin with unfractionated heparin in primary percutaneous coronary intervention (from the ATOLL trial).&nbsp;Reference:&nbsp;Collet et al. Am J Cardiol. 2013; Epub ahead of print. ATOLL study analysis suggests that enoxaparin is superior to unfractionated heparin in reducing ischemic events and mortality in patients&nbsp; suffering ST elevation acute myocardial infarction (STEMI)<a href="https://solaci.org/en/2013/09/16/enoxaparin-appears-superior-to-unfractionated-heparin-in-patients-undergoing-primary-angioplasty/" title="Read more" >...</a>

Primary angioplasty , a race against time

Original title:&nbsp;Door-to-Balloon Time and Mortality among Patients Undergoing Primary PCI.&nbsp;Reference:&nbsp;Daniel S. Menees et al. N Engl J Med 2013;369:901-9. For more than a decade has been ranked , like a race, to the delay times that occur in hospitals until angioplasty is performed in the context of an infarct with ST segment elevation . Several<a href="https://solaci.org/en/2013/09/13/primary-angioplasty-a-race-against-time/" title="Read more" >...</a>

Carotid angioplasty prior to central venous catheter. The best option to solve combined problems.

Original title:&nbsp;A Direct Comparison of Early and Late Outcomes with Three Approaches to Carotid Revascularization and Open Heart Surgery.&nbsp;Reference:&nbsp;Mehdi H. Shishehbor et al. J Am Coll Cardiol, article in press. &nbsp; The prevalence of severe carotid stenosis (&gt; 80%) in patients planning to have a Central Venous Catheter (CVC) is estimated at between 6 and<a href="https://solaci.org/en/2013/08/08/carotid-angioplasty-prior-to-central-venous-catheter-the-best-option-to-solve-combined-problems/" title="Read more" >...</a>

The Importance of TIMI 3 flow in primary angioplasty

Original title:&nbsp;Predicitors of suboptimal TIMI flow alter primary angioplasty for acute myocardial infarction: results from the HORIZON-AMI trial.&nbsp;Reference:&nbsp;Adriano Caixeta et al. &nbsp;Eurointervention 2013;9:220-227 Primary angioplasty showed greater efficacy than thrombolytics but one out of every four patients cannot achieve TIMI 3 flow. The Horizons-AMI trial randomized 3,602 patients to receive bivalirudin or heparin plus inhibitors<a href="https://solaci.org/en/2013/07/05/the-importance-of-timi-3-flow-in-primary-angioplasty/" title="Read more" >...</a>

DES versus Bare in primary angioplasty at five years. Initial advantage is reducing

Original: title&nbsp;Long-Term Outcome After Drug-Eluting VersusBare-Metal Stent Implantation in Patients WithST-Segment Elevation Myocardial Infarction. 5 Years Follow-Up From the Randomized DEDICATION (Drug Elution and DistalProtection in Acute Myocardial Infarction) Trial.&nbsp;Reference:&nbsp;Lene Holmvang et al. J Am CollCardiolIntv 2013, article in press. &nbsp; Primary angioplasty reduced mortality and reinfarction compared with thrombolytics in patients experiencing an ST<a href="https://solaci.org/en/2013/07/05/des-versus-bare-in-primary-angioplasty-at-five-years-initial-advantage-is-reducing/" title="Read more" >...</a>

A real challenge: Primary PCI on an Unprotected Left Main Coronary Culprit Lesion

Original title:&nbsp;A Systematic Review and Meta-Analysis on Primary Percutaneous Coronary Intervention on an Unprotected Left Main Coronary Artery Culprit Lesion in the setting of Acute Myocardial Infarction&nbsp;Reference:&nbsp;Marije M. Vis et al. J Am Coll Cardiol Intv 2013;6:317&ndash;24 Acute myocardial infarction with a significantly compromised unprotected left main coronary artery culprit lesion is relatively rare (4%<a href="https://solaci.org/en/2013/04/24/a-real-challenge-primary-pci-on-an-unprotected-left-main-coronary-culprit-lesion/" title="Read more" >...</a>

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