Original title: A Prospective Randomized Trial of Trombectomy Versus No Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesion. MUSTELA (MUltidevice Thrombectomy in Acute ST-Segment ELevation Acute Myocardial Infarction) Trial Reference: Marco De Carlo, et al. J Am Coll Cardiol Intv 2012;5:1223–30 The main objective during primary PCI is myocardial reperfusion, which is limited by distal<a href="https://solaci.org/en/2013/01/10/thrombus-aspiration-is-useful-in-ami/" title="Read more" >...</a>
Does the systematic use of clopidogrel reduce events prior to angioplasty?
Original title: Association of Clopidogrel Pretreatment with mortality, Cardiovascular events, and Major Bleeding among patients undergoing percutaneous coronary intervention. A systematic review and Mata-analysis. Reference: Anne Bellemain-Appaix, MD et al. for the ACTION group. The loading of clopidogrel before coronary angioplasty is an accepted practice by most clinical and interventional cardiologists but, nevertheless, it is only based on<a href="https://solaci.org/en/2013/01/02/does-the-systematic-use-of-clopidogrel-reduce-events-prior-to-angioplasty/" title="Read more" >...</a>
Self-expanding stents improve positioning in primary angioplasty
Original title: Self-Expanding Versus Balloon-Expandable Stents in Acute Myocardial Infarction: Results From the APPOSITION II Study Reference: Robert-Jan van Geuns et al. J Am Coll Cardiol Intv 2012;5:1209–19 Acute myocardial infarction is associated with vasoconstriction and thrombus occlusion. Resolution of these two points during the first hours after primary angioplasty can lead to poor extension and poor positioning<a href="https://solaci.org/en/2012/12/21/self-expanding-stents-improve-positioning-in-primary-angioplasty/" title="Read more" >...</a>
Tres Reglas para Identificar Infarto en la Guardia
Prioridad en la Evaluación Electrocardiográfica Inmediata en la Guardia: Validación de un Algoritmo En las actuales directrices internacionales se recomienda la inmediata realización ( Con el objeto de identificar los escenarios clínicos asociados a la presentación de un paciente con IAMST, un estudio epidemiológico recientemente publicado analizó todos los casos registrados durante el período 2007<a href="https://solaci.org/en/2011/01/01/tres-reglas-para-identificar-infarto-en-la-guardia-2/" title="Read more" >...</a>
ULTIMATE III: Use of IVUS for Coronary De Novo Lesion Drug Coated Balloon Angioplasty
Percutaneous coronary intervention (PCI) with drug eluting stents (DES) can present limitations, especially in the form of stent thrombosis or instent restenosis (ISR). These findings have furthered the development of drub coated balloons (DCB). The safety and efficacy of DCB have already been shown in the context of ISR and de novo small vessel coronary<a href="https://solaci.org/en/2024/07/12/ultimate-iii-use-of-ivus-for-coronary-de-novo-lesion-drug-coated-balloon-angioplasty/" title="Read more" >...</a>
Complex PCI in Octogenarian
The octogenarian population has already reached 137 million and continues to grow. It is estimated to triple by 2050. This increase represents a big challenge, seeing as these patients are often more fragile, present more complex coronary artery disease and multiple comorbidities. This generally requires two or more procedures and more experience both from operators<a href="https://solaci.org/en/2024/06/18/complex-pci-in-octogenarian/" title="Read more" >...</a>
BIONYX: Onyx vs. Orsiro At 5 Years
Onyx is a zotarolimus-eluting stent (ZES), designed with thin struts and a platinum core that enhances its radiological visibility. This can be beneficial in complex situations with limited visibility, such as in patients who are obese or present severe calcification, two particularly frequent characteristics in diabetic or elderly patients. The BIONYX study was a randomized<a href="https://solaci.org/en/2024/06/05/bionyx-onyx-vs-orsiro-at-5-years/" title="Read more" >...</a>
TAVR in Bicuspid Valves
Bicuspid aortic valve (BAV) disease affects 1%-2% of the population and manifests with severe aortic stenosis in the middle-aged. It characterizes for a very different anatomy with more calcification than the tricuspid aortic valve. At present, surgical aortic valve replacement (SAVR) is the first treatment indication. TAVR in this scenario has shown, in different studies,<a href="https://solaci.org/en/2024/05/07/tavr-in-bicuspid-valves/" title="Read more" >...</a>
Lithotripsy in the Left Main Coronary Artery
A lesion ≥50% in the left main coronary artery (LMCA) is considered severe, according to various scientific societies, regardless of the presence of symptoms or ischemia, due to the extent of myocardium at risk. In such cases, revascularization is indicated. In many patients, lesions in this section of the coronary artery have severe calcification, which<a href="https://solaci.org/en/2024/03/13/lithotripsy-in-the-left-main-coronary-artery/" title="Read more" >...</a>
Should We Treat Obstructive Coronary Artery Disease in TAVI?
Coronary artery disease, both obstructive and non-obstructive, often coexists with significant aortic stenosis. Therapeutic decision-making in this scenario remains controversial, not only regarding the need for treatment, but also about when it should be addressed, considering its pros and cons. Various analyses have yielded contradictory data, as most lesions are chronic and stable. Currently, the<a href="https://solaci.org/en/2024/02/07/should-we-treat-obstructive-coronary-artery-disease-in-tavi/" title="Read more" >...</a>