stents

ISAR-TRIPLE: 6 weeks versus 6 months of clopidogrel in patients with oral anticoagulation and drug-eluting stent

There are a significant number of patients receiving drug-eluting stents and besides, require oral anticoagulation. The combination of anticoagulants, aspirin, and clopidogrel greatly increases the rate of bleeding, because of this, the time of the triple scheme should be as short as possible.&nbsp; The aim of this study was to compare the triple therapy for<a href="https://solaci.org/en/2015/06/24/isar-triple-6-weeks-versus-6-months-of-clopidogrel-in-patients-with-oral-anticoagulation-and-drug-eluting-stent/" title="Read more" >...</a>

SECURITY: 6 months versus 12 months of dual anti-aggregation using 2nd generation DES

This multicenter noninferiority design work included 1399 patients randomized to receive 6 months (n = 682) versus 1 year (n = 717) dual anti-aggregation after implantation of 2nd generation drug-eluting stent. The primary end point was a composite of cardiac death, myocardial infarction, stroke, definite or probable thrombosis, and major bleeding. At 12 months follow-up<a href="https://solaci.org/en/2015/06/24/security-6-months-versus-12-months-of-dual-anti-aggregation-using-2nd-generation-des/" title="Read more" >...</a>

OCT-STEMI: Primary angioplasty guided by OCT

This study included 201 patients suffering ST-segment elevation acute coronary syndrome and randomized to the use of optical coherence tomography (OCT) versus conventional angiography for the procedure. OCT-guided group used more stents per patient (1.4 versus 1.2, p = 0.03) and greater release pressure. During control OCT suboptimal results were found in a third of<a href="https://solaci.org/en/2015/06/24/oct-stemi-primary-angioplasty-guided-by-oct/" title="Read more" >...</a>

CTO-IVUS: IVUS clinical impact in total occlusions with 2nd generation DES

While the use of intravascular ultrasound (IVUS) during coronary intervention proved useful in multiple studies, there is limited evidence in the literature regarding its use in specifically in chronic total occlusions. The IVUS may help guide in recognizing the true lumen and better distal positioning, better coverage of stent, an optimal apposition and expansion, diagnose<a href="https://solaci.org/en/2015/06/24/cto-ivus-ivus-clinical-impact-in-total-occlusions-with-2nd-generation-des/" title="Read more" >...</a>

DKCRUSH-VI: FFR versus conventional angiography in true bifurcations and provisional stent

The aim of this study was to compare angioplasty guided by fractional flow reserve (FFR) versus conventional angiography in bifurcations treated with provisional stent technique for lateral branch. The study included patients with bifurcations 1,1,1 or 0,1,1 of Medina classification and lateral branches, superior to 2.5 mm. 2nd generation pharmacological stents were used.&nbsp; After stent<a href="https://solaci.org/en/2015/06/24/dkcrush-vi-ffr-versus-conventional-angiography-in-true-bifurcations-and-provisional-stent/" title="Read more" >...</a>

RIBS IV: Drug-eluting balloon versus everolimus-eluting stent on in-stent restenosis

This prospective, multicenter, randomized trial compared the paclitaxel-eluting balloon versus everolimus-eluting stent to treat patients with in-stent restenosis. 309 patients were included in total (154 received the drug-eluting balloon, and 155 received the everolimus-eluting stent). There were no differences in the characteristics of both groups. At one year the rate of cardiac death, myocardial infarction<a href="https://solaci.org/en/2015/06/24/ribs-iv-drug-eluting-balloon-versus-everolimus-eluting-stent-on-in-stent-restenosis/" title="Read more" >...</a>

TITAN-AMI: Final results of bio-active coated stent

Previous studies suggest the excellent performance of the bioactive coated stent TITAN 2 compared with drug-eluting stents (DES). The aim of the study was to evaluate the results of this device in patients undergoing both ST segment elevation and without ST segment elevation acute coronary syndrome. A total of 1066 patients were included, of whom<a href="https://solaci.org/en/2015/06/24/titan-ami-final-results-of-bio-active-coated-stent/" title="Read more" >...</a>

TRYTON: dedicated stent for bifurcations not inferior than the provisional technic

This study compared the clinical and angiographic results of the use of the provisional stent technique versus the 2 stents technique (TRYTON device at the side branch) in true bifurcations.&nbsp; The study with non-inferiority design, randomized 704 patients in total to drug-eluting stent in the main branch plus the TRYTON device in the side branch<a href="https://solaci.org/en/2015/06/24/tryton-dedicated-stent-for-bifurcations-not-inferior-than-the-provisional-technic/" title="Read more" >...</a>

COBRA: culotte technique versus self-expanding dedicated stent to treating bifurcations

This work compared the safety and efficacy of the culotte technique versus the use of self-expanding Biolimus A9 (AXXESS) eluting stent evaluating the healing of the vessel by OCT besides quantitative angiography and clinical events. In one, group (n = 20) bifurcated stent system AXXESS plus everolimus-eluting stents in the main distal branch and side<a href="https://solaci.org/en/2015/06/24/cobra-culotte-technique-versus-self-expanding-dedicated-stent-to-treating-bifurcations/" title="Read more" >...</a>

CIBELES: Xience V comparative study vs Cypher for the treatment of total chronic occlusions.

Spanish-Portuguese multicentre CIBELES study (Raul Moreno, Madrid, Spain) compared two drug-eluting stents &#8211; an everolimus (Xience V, Abbott Vascular, USA) and a sirolimus-releasing eluting stent (Cypher Select, Cordis Corporation, Miami Lakes, Florida, USA) in the context of total chronic coronary occlusions. With a non-inferiority design, the study randomized 208 patients (1:1), using as the primary<a href="https://solaci.org/en/2015/06/24/cibeles-xience-v-comparative-study-vs-cypher-for-the-treatment-of-total-chronic-occlusions/" title="Read more" >...</a>

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