angioplasty

PRAGUE 19: bioabsorbable platform for patients with ST segment elevation

Absorbable bioplatforms are considered safe and effective in stable patients but their use in the context of acute myocardial infarction with ST segment elevation has not been reported. Low risk of heart attack with low Killip classification could be the stage for this device. 87 consecutive patients experiencing myocardial infarction with ST elevation underwent primary<a href="https://solaci.org/en/2015/06/24/prague-19-bioabsorbable-platform-for-patients-with-st-segment-elevation/" title="Read more" >...</a>

SCAAR: Heparin versus bivalirudin in patients with myocardial infarction without ST segment elevation.

We evaluated 41,537 patients admitted with myocardial infarction without ST elevation on the SCAAR register and who had not received IIBIIIB glycoprotein inhibitors and divided them into two groups: 31,351 patients who received heparin versus 10,186 who received bivalirudin. We adjusted baseline characteristics of the two groups using the Propensity score with the exception of<a href="https://solaci.org/en/2015/06/24/scaar-heparin-versus-bivalirudin-in-patients-with-myocardial-infarction-without-st-segment-elevation/" title="Read more" >...</a>

SYNTAX II: multiple vessels using iFR / FFR and IVUS

This study is still in progress and includes patients using SYNTAX II score based on functional invasive evaluation with iFR / FFR and performing angioplasty guided by IVUS using the biodegradable polymer everolimus eluting stent. The study seeks to prove superiority versus the first generation paclitaxel-eluting stent and non-inferiority versus surgery using historical data. We<a href="https://solaci.org/en/2015/06/24/syntax-ii-multiple-vessels-using-ifr-ffr-and-ivus/" title="Read more" >...</a>

FREEDOM: Insulin dependent versus non-insulin dependent with multivessel disease

From the total of 1900 patients in the FREEDOM study, 1248 did not require insulin (631 received angioplasty and 617 received CABG) and 602 if required (325 received angioplasty and 277 received CABG). Insulin dependent patients were more obese, with higher glycosylated hemoglobin, increased incidence of heart failure and increased incidence of acute coronary syndromes.<a href="https://solaci.org/en/2015/06/24/freedom-insulin-dependent-versus-non-insulin-dependent-with-multivessel-disease/" title="Read more" >...</a>

HYBRID: Hybrid revascularization in patients with multi-vessel

We included 200 patients (100 with hybrid revascularization and 100 with conventional surgery). The complete revascularization rate was similar between both groups (70%). Also, the event-free survival was similar with 92% for conventional surgery group and 89% for the hybrid. The revascularization of the anterior descending artery with breast bridge and angioplasty to the rest<a href="https://solaci.org/en/2015/06/24/hybrid-hybrid-revascularization-in-patients-with-multi-vessel/" title="Read more" >...</a>

LEVANT 2: Initial results from the new drug eluting balloon for femoropopliteal lesions

This prospective multicenter study randomized 476 patients 2:1 to paclitaxel eluting balloon versus conventional balloon for femoropopliteal region lesions with the primary objective of assessing death, free amputationsurvival and reintervention at 6 months. At 6 months follow-up a higher rate of restenosis with conventional balloon was observed.These are preliminary results and we must wait for<a href="https://solaci.org/en/2015/06/24/levant-2-initial-results-from-the-new-drug-eluting-balloon-for-femoropopliteal-lesions/" title="Read more" >...</a>

RIBS V: Pharmacological balloon vs second-generation drug-eluting stent in the treatment of BMS restenosis

The ideal therapy for treating in-stent restenosis continues to be debated . The pharmacological balloons showed good results in this context, but no direct comparisons available of pharmacological balloonsversus second-generation DES.This prospective, multicenter randomized 189 patients with in-stent restenosis of conventional stents receiving pharmacological balloon or everolimusDES.The primary endpoint was angiographicat 9 months spotting a<a href="https://solaci.org/en/2015/06/24/ribs-v-pharmacological-balloon-vs-second-generation-drug-eluting-stent-in-the-treatment-of-bms-restenosis/" title="Read more" >...</a>

SAFE-PCI for Women: Radial versus femoral access for women

Radial access is associated with a lower rate of vascular and bleeding complications however female patients with smaller diameter arteries such access might be technically more difficult. This prospective, randomized, multicenter study compared both approaches in the context of coronary angioplasty in female patients. 1787 patients were randomized (893 in the radial group and 894<a href="https://solaci.org/en/2015/06/24/safe-pci-for-women-radial-versus-femoral-access-for-women/" title="Read more" >...</a>

PRAMI: Treating other lesions in addition to the culprit of an acute infarction reduces events.

In the context of an ST-segment elevation myocardial infarction, primary angioplasty to treat the culprit lesion improves the prognosis. The role of angioplasty in unrelated arteries is not well established. Between 2008 and 2013, 465 patients with myocardial infarction underwent primary angioplasty and were randomized to preventive (234 patients) vs non-preventive angioplasty (231 patients). The<a href="https://solaci.org/en/2015/06/24/prami-treating-other-lesions-in-addition-to-the-culprit-of-an-acute-infarction-reduces-events/" title="Read more" >...</a>

PARIS: Interruption of dual antiplatelet treatment can be safe depending on the clinical context and treatment time

The cessation of dual antiplatelet treatment increased the risk of post coronary intervention adverse events. It is unclear whether the risk varies through time or if it depends on the reason for the interruption or both. The PARIS (patterns of non-adherence to anti-platelet regimens in stented patients) register is a prospective, observational study in patients<a href="https://solaci.org/en/2015/06/24/paris-interruption-of-dual-antiplatelet-treatment-can-be-safe-depending-on-the-clinical-context-and-treatment-time/" title="Read more" >...</a>

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