This study evaluated the safety and effectiveness of the CoreValve transcatheter valve replacement in patients with severe aortic stenosis with extreme risk for surgery. The primary end point was a composite of all-cause mortality and stroke at 24 months. The rate of death from any cause or cerebrovascular accident at 24 months was 38% for...
PARTNER cohort B: 5-year results of a balloon-expandable valve on inoperable patients
This study included 358 patients considered inoperable, randomized to TAVR with expandable balloon valve versus conservative treatment. The 5-year end points included all-cause mortality, cardiac mortality, re-hospitalization, and stroke. At 5 years, mortality from all causes was lower in TAVR group versus conservative treatment group (71.8% versus 93.6%, P <0.0001). By dividing patients by STS...
CLEAN-TAVI: transcatheter aortic valve replacement with cerebral protection
The stroke is a leading complication of post transcatheter aortic valve implantation increasing up to 3 times the mortality of these patients. In the works performed neuroimaging new post, TAVR defects were observed in two-thirds of patients and this increases the risk of post clinical stroke. There is a missing data in the literature of...
American Registry for percutaneous aortic valve replacement,one-year evolution of nearly 6000 patients
TVT STS / ACC registrywas developed to obtain data from all patients undergoing percutaneous aortic valve replacement (TAVR) in the United States. The clinical outcome at 30 days was recently published (Macket al, JAMA 2013) but there are few data on the longer-term treatment that is already incorporated in clinical practice in the United States.The...
CoreValve superior to surgical aortic valve replacement in high-risk patients
The aim of this study was to compare percutaneous aortic valve replacement (TAVR) with the self-expanding Valve Core with conventional surgery in patients at high surgical risk. Patients with a valve area < 0.8 cm2 , valvular index ≤ 0.5 cm2 , a mean gradient of > 40 mmHg or peak speeds above 4m /s...
PARTNER cohort B: Clinical events at 3 years follow-up in patients with
Background: Percutaneous aortic valve implantation (TAVI) is the treatment of choice for patients with severe aortic stenosis considered inoperable according to clinical outcomes at 12 months as reported in the PARTNER study, which demonstrated a reduction in mortality and an improvement in the quality of life for patients. However, the long term benefit of this...
Educational Journal N° 98
1. ESTUDIOS DE TECNOLOGIAS EN INTERVENCIONES CORONARIAS • RIBS IV – Presentador: Fernando Alfonso • ABSORB II – Presentador: Patrick Serruys 2. ESTUDIOS DE FARMACOLOGIA EN INTERVENCIONES CORONARIAS • ISAR-TRIPLE – Presentador: Nikolaus Sarafoff • SECURITY – Presentador: Antonio Colombo • BRIGHT – Presentador: Yalin Hang 3. ESTUDIOS EN IMÁGENES CORONARIAS • IVUS-CTO – Presentador:...
Results of the new repositionable and retrievable percutaneous valve system
Original title: Transcatheter Aortic Valve Replacement for Severe Symptomatic Aortic Stenosis Using a Repositionable Valve System. 30-Day Primary Endpoint Results From the REPRISE II Study. Reference: Ian T. Meredith AM et al. J Am Coll Cardiol 2014;64:1339–48. Transcatheter aortic valve replacement (TAVR) showed results comparable to those of surgery in patients at high surgical risk, but complications can...
Stress echocardiography in low flow, low gradient aortic stenosis with deteriorated systolic function
Echocardiography Favaloro Foundation. Buenos Aires, Argentina. JACC Cardiovascular Imaging has recently published a retrospective analysis including severe aortic stenosis patients (< 1 cm²), with low gradient (mean aortic gradient Patients that had undergone dobutamine stress echocardiography (DSE) to distinguish pseudo aortic stenosis (n=49) were selected. These results were used to determine flow reserve (FR). The...
The delay between the indication and the embodiment of the procedure decrease the effectiveness of percutaneous aortic valve replacement
Original title: Impact of wait times on the effectiveness of transcatheter aortic-valve replacement (TAVR) in severe aortic valve disease: a discrete event simulation model. Reference: Wijeysundera HC et al. Can J Cardiol. 2014; Epub ahead of print. Once patients are accepted for percutaneous aortic valve replacement (TAVR), the higher the expected for the valve, the greater the risk...