The new generation SAPIEN 3 valve was designed to reduce paravalvular aortic regurgitation. The objective of this work was to evaluate the influence of “oversizing” for SAPIEN 3 valve both in relation to the area and the perimeter and determine if calcium ring influences the degree of failure.

A lesser degree of oversizing need it to prevent moderate to severe aortic failure was observed. Being the ideal valve size 0 to 5% more than the size of the ring. The higher the valvular calcification degree index, higher the degree of aortic failure post procedure.

Conclusion

The study showed SAPIEN 3valve has low rate of moderate to severe aortic regurgitation in a low oversizing scenario.

Philipe Blanke
2015-05-20

Original title: Influence of computed tomography-based over-sizing on the incidence of paravalvular regurgitation of a new-generation transcatheter valve: early results of the intermediate-risk S3 cohort PARTNER II trial.