The pressure ratio in the resting phase of the cardiac cycle is a newly Introduced procedure for the assessment of coronary stenoses based on pressure measurement without adenosine. It generated interest with over 1500 comparisons with the FFR since its introduction at TCT 2011. The discrepancies between the two methods have been attributed to the<a href="https://solaci.org/en/2015/06/24/advise-ii-functional-assessment-of-coronary-lesions-without-adenosine/" title="Read more" >...</a>
The first simulated 3D heart has been presented and could predict responses to treatments
Dassault Systèmes announces the launch of the first model of the world based on virtual 3D simulation of the whole human heart. Developed with a multidisciplinary team of experts to help fight cardiovascular disease, “Living Heart” project will mark a new frontier in the diagnosis, treatment and prevention of heart disease through personalized 3D virtual<a href="https://solaci.org/en/2015/06/01/the-first-simulated-3d-heart-has-been-presented-and-could-predict-responses-to-treatments/" title="Read more" >...</a>
DES and programmed surgery: reality or myth
Original title: Drug-Eluting Stents versus Bare Metal Stents Prior to Noncardiac Surgery. Reference: Sripal Bangalore, et al. Catheterization and Cardiovascular Intervention 2015;85:533-41 Drug eluting stents (DES) have proved beneficial compared to bare metal stents (BMS), but the need to program a surgical procedure after a percutaneous coronary intervention (PCI) has limited its use. This study analyzed patients receiving<a href="https://solaci.org/en/2015/05/12/des-and-programmed-surgery-reality-or-myth/" title="Read more" >...</a>
CTO revascularization is beneficial
Título original: Long-Term Survival Benefit of Revascularization Compared UIT Medical Therapy in Practice UIT Coronary Chronic Total Occlusion and Well-Developed Collateral Circulation. Reference: Woo Jin Jan, el at. J Am Coll Cardiol Interv 2015;8:271-9 Multiple studies have shown the benefit of chronic total occlusion (CTO) revascularization, but for patients presenting Rentrop 3 grade collateral circulation (CC), such benefit<a href="https://solaci.org/en/2015/03/24/cto-revascularization-is-beneficial/" title="Read more" >...</a>
Impact of kidney function on TAVI outcome
Original title: Impact of chronic kidney disease on the outcome of transcatheter aortic valve implantation: results from the FRANCE 2 Registry. Reference: Atsushi Oguri, et al. EuroIntervention 2015;10:e1-9 Globally, 13% of patients present kidney failure, which has been associated to a worse evolution not only of TAVI outcomes but also of other cardiovascular intervention outcomes. Most studies, including<a href="https://solaci.org/en/2015/02/19/impact-of-kidney-function-on-tavi-outcome/" title="Read more" >...</a>
Outcomes are still associated to operator experience and institutional volume
This study is a retrospective analysis of 2,243,209 PCI stenting procedures in the USA between 2005 and 2009. During this period, a reduction in the number of PCI procedures was observed (also observed globally) from 53 in previous years to 33 procedures per operator per year, and from 1,024 to 693 per hospital per year.<a href="https://solaci.org/en/2014/10/08/outcomes-are-still-associated-to-operator-experience-and-institutional-volume/" title="Read more" >...</a>
Worse post TAVI ejection fraction recovery in coronary artery disease patients without revascularization
Original title: Impact of coronary artery disease on left ventricular ejection fraction recovery following transcatheter aortic valve implantation. Reference: Freixa X et al. Catheter Cardiovasc Interv. 2014;Epub ahead of print. This single center study analyzed data form 56 consecutive patients with severe aortic stenosis and LVEF of ≤ 50% undergoing TAVI (transcatheter aortic valve implantation) between March 2006<a href="https://solaci.org/en/2014/10/06/worse-post-tavi-ejection-fraction-recovery-in-coronary-artery-disease-patients-without-revascularization/" title="Read more" >...</a>
The permanent pacemaker implantation after TAVI does not negatively impact on the results or even helps
Original title: Pacemaker implantation following transcatheter aortic valve implantation: Impact on late clinical outcomes and left ventricular function. Reference: Urena M et al. Circulation. 2014 Mar 18;129(11):1233-43. The need for permanent pacemaker implantation (PPI) is one of the most frequent complications associated with TAVI. Although data suggest that right ventricle stimulation has a potential negative impact, the<a href="https://solaci.org/en/2014/07/24/the-permanent-pacemaker-implantation-after-tavi-does-not-negatively-impact-on-the-results-or-even-helps/" title="Read more" >...</a>
Prognostic factors for early mortality in patients undergoing TAVI; Individual risk calculation using a simple score: Derivative analysis from FRANCE II Registry.
Original title: Predictive factors of early mortality after transcatheter aortic valve implantation: individual risk assessment using a simple escore. Reference: Heart. 2014 Apr 16. doi: 10.1136/heartjnl-2013-305314. Epub ahead of print. The decision to perform an intervention in symptomatic aortic stenosis must balance surgery or transcatheter aortic valve implantation (TAVI) risk. Factors associated with early mortality after TAVI<a href="https://solaci.org/en/2014/04/30/prognostic-factors-for-early-mortality-in-patients-undergoing-tavi-individual-risk-calculation-using-a-simple-score-derivative-analysis-from-france-ii-registry/" title="Read more" >...</a>
3rd generation zotarolimus-eluting stent non- inferior to everolimus
Original title: Third-generation zotarolimus-eluting and everolimus-eluting stents in all-comer patients requiring a percutaneous coronary intervention (DUTCH PEERS): a randomized, single-blind, multicentre, non-inferiority trial. Reference: Von Birgelen C et al. The Lancet. 2014; Epub ahead of print. In the 3rd generation zotarolimus-eluting stent, platform was modified to increase flexibility and make implant easier in complex lesions. This study was<a href="https://solaci.org/en/2014/02/13/3rd-generation-zotarolimus-eluting-stent-non-inferior-to-everolimus/" title="Read more" >...</a>