Coronary microvascular dysfunction (CMD) is a paramount factor involved in the development of anginal syndromes. Among patients with angina and nonobstructive coronary artery disease with CMD, two patterns have been identified using minimal microvascular resistance: structural CMD, and functional CMD. Structural CMD is characterized by decreased coronary flow reserve (CFR) in the presence of increased...
Positron emission tomography (PET) with F sodium fluoride (F-NaF) allows for the assessment of microcalcification activity (MA) in a wide variety of cardiovascular conditions, including atherosclerosis. In coronary artery disease, this tracer correlates with progressive disease and allows for the prediction of atherosclerosis progression. Unlike PETs, computed tomography (CT) allows for the evaluation of an...
According to this new meta-analysis (presented at AHA 2021 and published in The Lancet), mortality is similar between surgery and angioplasty to treat left main coronary artery in patients with simple or intermediate anatomy. This new study estimates that, after 5 years, mortality with surgery would be 11.2% vs. 10.2% with angioplasty, a non-significant difference. This debate...
✔️ Watch again the session “Current & Immediate Future Role of Imaging in Structural and Coronary Heart Disease” in the SOLACI-CACI 2021 Congress. 👨🏫 Program: 02:27 – Computer Tomography in TAVR: Planning, Predicting Complications, and Follow-up – Mariano Falconi 19:26 – Multi-Imaging Evaluation in Mitral Regurgitation Intervention – Fabián Salmo 31:10 – New Prognosis Tools...
After 10 years of follow-up, there were no significant differences in the rates of major adverse cardiovascular or cerebrovascular events among patients with left main coronary artery disease randomized to angioplasty or surgery. Since this was the first study to randomize patients with left main coronary artery disease to angioplasty or surgery, it enrolled very few...
Low grade inflammation shown by elevated plasma concentrations of high-sensitive C-reactive protein are a risk factor for coronary artery disease (CAD) patients. There is also evidence to support low grade inflammation could be related to higher risk of cancer. This prospective study evaluated the relation between low grade systemic inflammation and the risk of cancer in...
The use of ticagrelor in patients with stable coronary artery disease significantly reduces the rate of major cardiovascular events when compared against aspirin, according to this study presented on Sunday at ESC 2019 simultaneously published in NEJM, though the cost in terms of major bleeding seems unacceptable. Primary end point rate (composite of cardiovascular death,...
The II International Symposium on Innovations in the Treatment of Coronary Artery Disease and Structural Heart Disease will take place on July 31st, 2019 at the Syrian-Lebanese Hospital in São Paulo. This event seeks to provide a better understanding of indications and clinical and interventional strategies for complex heart conditions, such as left main coronary...
We need more evidence to guide us in the management of silent ischemia. Confirmed asymptomatic coronary artery disease is a problem for cardiologists, who lack enough evidence to guide a risk-benefit assessment that justifies revascularization. Revascularizing the outcome of a functional assessment may reduce the rates of death and infarction, or it may just be...
Several studies (some of them recent, some of them not so much so) have compared left main coronary artery angioplasty and myocardial revascularization surgery. Combined, these works compose a large corpus of evidence, but follow-up has not gone beyond 5 years in any case. The main aim of this study (presented at TCT 2018 and published simultaneously...