Optimal Duration of DAPT: How to Predict Long-Term Events

Courtesy of Dr. Santiago F. Coroleu.   Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel after percutaneous coronary intervention (PCI) reduces the risk for coronary thrombotic events (CTEs) at the expense of increasing risk for major bleeding (MB). However, the lack of information to accurately predict the occurrence of each event in out-of-hospital patients under<a href="https://solaci.org/en/2016/08/17/optimal-duration-of-dapt-how-to-predict-long-term-events/" title="Read more" >...</a>

DES in primary PCI: The Best Option?

Courtesy of Dr. Brian Nazareth Donato.   The relative safety of drug-eluting stents (DES) and conventional bare-metal stents (BMS) in primary angioplasty (percutaneous coronary intervention, PCI) in patients with ST elevation myocardial infarction (STEMI) is still subject of debate.   A search was carried out using Medline, CENTRAL, EMBASE, TCTMD and Cardiosource. There were 9673 patients included,<a href="https://solaci.org/en/2016/08/10/des-in-primary-pci-the-best-option/" title="Read more" >...</a>

BVS: Comparable to Second-Generation DES in Complex Lesions

A center carrying out a mid- to long-term follow-up of the performance of everolimus-eluting bioresorbable scaffolds (Absorb) observed that this new device has an acceptable rate of major cardiovascular events, when compared to second-generation drug-eluting stents. Furthermore, although the population was complex and non-selected, no cases of early thrombosis were reported. This study enrolled 249 patients<a href="https://solaci.org/en/2016/08/03/bvs-comparable-to-second-generation-des-in-complex-lesions/" title="Read more" >...</a>

Non-Compliant Balloons Improve Bifurcation Outcomes

Courtesy of Dr. Carlos Fava. The provisional approach is the standard strategy to treat bifurcations, but it might cause dissection of the ostium, a serious complication of the side branch. The use of non-compliant balloons (NCB) ensures uniform, constant, and controlled expansion along balloon length, reducing the risk of dissection. The COBIS II registry enrolled<a href="https://solaci.org/en/2016/08/01/non-compliant-balloons-improve-bifurcation-outcomes/" title="Read more" >...</a>

DAPT after PCI with EES: 6 or 12 Months?

Original Title: 6-Month versus 12-Month Dual-Antiplatelet Therapy Following Long Everolimus-Eluting Stent Implantation. The IVUS-XPL Randomized Clinical Trial. Reference: Hong et al. JACC Cardiovasc Interv. 2016 May 11. [Epub ahead of print]   Courtesy of Dr. Brian Nazareth Donato.   This publication stems from the IVUS-XPL published by JAMA in November 2015. This study presents outcomes on the<a href="https://solaci.org/en/2016/07/25/dapt-after-pci-with-ees-6-or-12-months/" title="Read more" >...</a>

stent liberador de drogas protusion de placa

Tissue Protrusion after DES: Adverse Events at Long Term?

Original Title: Tissue Protrusion after Stent Implantation. An ADAPT-DES Intravascular Ultrasound Substudy. Reference: Fuyu Qiu et al. J Am Coll Cardiol Intv. 2016;9(14):1499-1507.   After DES implantation we may observe tissue protrusion (plaque or thrombus) relatively often, especially in unstable lesions; however, its clinical impact has not been studied. The aim of this study was<a href="https://solaci.org/en/2016/07/21/tissue-protrusion-after-des-adverse-events-at-long-term/" title="Read more" >...</a>

balon_farmacologico_reestenosis_instrastent

DEB, the Best Option to Treat Superficial Femoral ISR

Original Title: Paclitaxel-eluting balloon versus standard balloon angioplasty in in-stent restenosis of the superficial femoral and proximal popliteal artery: 1-year results of the PACUBA trial. Reference: Kinstner CM et al. J Am Coll Cardiol Intv. 2016;9:1386-1392.   Patients with symptomatic femoropopliteal in-stent restenosis (ISR) have better patency at one year if treated with drug eluting<a href="https://solaci.org/en/2016/07/13/deb-the-best-option-to-treat-superficial-femoral-isr/" title="Read more" >...</a>

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Stent Fracture: More Frequent than Expected

Original Title: Incidence and Clinical Outcome of Stent Fractures on the Basis of 6555 Patients and 16482 Drug Eluting Stents From 4 Centers. Reference: Kan J et al. JACC Cardiovasc Interv. 2016 Jun 13;9(11):1115-23. Courtesy of Dr. Guillermo Migliaro. Stent fracture (SF) has been associated with instent restenosis (ISR), stent thrombosis (ST) and repeat revascularization<a href="https://solaci.org/en/2016/06/28/stent-fracture-more-frequent-than-expected/" title="Read more" >...</a>

Instent restenosis: Drug eluting balloons or drug eluting stents?

Original Title: Long-Term Results of Everolimus-Eluting Stents versus Drug-Eluting Balloons in Patients with Bare-Metal In-Stent Restenosis 3-Year Follow-Up of the RIBS V Clinical Trial. Reference: Alfonso F. et al. JACC Cardiovasc Interv. 2016 Jun 27;9(12):1246-55.   Courtesy of Dr. Agustín Vecchia.   RIBS V 3 year follow up Stents have become the gold standard for<a href="https://solaci.org/en/2016/06/28/instent-restenosis-drug-eluting-balloons-or-drug-eluting-stents/" title="Read more" >...</a>

STEMI: Best P2Y12 inhibitor according to network meta-analysis

Original Title: Optimal P2Y12 inhibitor in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a network meta-analysis. Reference: Rafique AM et al. J Am Coll Cardiol Intv 2016;9:1036–46.   Courtesy of Dr. Alejandro Lakowsky.     Researchers drew up a network meta-analysis incorporating 37 trials with more than 88,000 patients undergoing ST elevation<a href="https://solaci.org/en/2016/06/22/stemi-best-p2y12-inhibitor-according-to-network-meta-analysis/" title="Read more" >...</a>