acute myocardial infarction

Intracoronary enalaprilat reduces periprocedural injury.

Original title:&nbsp;Intracoronary Enalaprilat to Reduce Microvascular Damage During Percutaneous Coronary Intervention (ProMicro) Study.&nbsp;Reference:&nbsp;Fabio Mangiacapra et al. J Am Coll Cardiol 2013. Article in press Angiotensin converting enzyme (ACE) inhibitors improve clinical outcomes in patients with coronary artery disease and improve epicardial flow in patients with acute ST-segment elevation.&nbsp; Beyond the long-term protective effect of oral<a href="https://solaci.org/en/2013/01/22/intracoronary-enalaprilat-reduces-periprocedural-injury/" title="Read more" >...</a>

Serum fibrinogen is a better predictor of periprocedural events than platelet reactivity.

Original title:&nbsp;Elevated Plasma Fibrinogen Rather Than Residual Platelet Reactivity After Clopidogrel Pre-Treatment Is Associated With an Increased Ischemic Risk During Elective Percutaneous Coronary Intervention.&nbsp;Reference:&nbsp;Lawrence Ang et al. J Am Coll Cardiol 2013;61:23&ndash;34. Platelet function tests have identified differences in the response of each patient to clopidogrel and minor platelet inhibition has been associated with thrombotic<a href="https://solaci.org/en/2013/01/09/serum-fibrinogen-is-a-better-predictor-of-periprocedural-events-than-platelet-reactivity/" title="Read more" >...</a>

Ticagrelor, even better than we thought

Original title:&nbsp;Reduction in First and Recurrent Cardiovascular Events with Ticagrelor Compared with Clopidogrel in the PLATO Study.&nbsp;Reference:&nbsp;Payal Kohli et al. CIRCULATION AHA.112.124248. In analyzing randomized and monitored study outcomes, we usually observe that after the occurrence of any primary outcome event patients are typically blocked for further analysis.&nbsp; This practice limits the information on subsequent<a href="https://solaci.org/en/2013/01/08/ticagrelor-even-better-than-we-thought/" title="Read more" >...</a>

Are reversal flow cerebral protection devices useful in carotid angioplasty?

Original title:&nbsp;Prospective, Multicenter European Study of the GORE Flor Reversal System for Providing Neuroprotection During Carotid Artery Stenting&nbsp;Reference:&nbsp;Dimitrios Nikas, et, al.Catheterization and Cardiovascular Intervention 80:1060-1068&nbsp; Cerebral protection systems (CPS) have proved useful in carotid angioplasty stenting (CAS), although it is not clear what the advantages are in respect to carotid endarterectomy, except in high risk<a href="https://solaci.org/en/2012/12/12/are-reversal-flow-cerebral-protection-devices-useful-in-carotid-angioplasty/" title="Read more" >...</a>

Complex angioplasty with ventricular assist

Original title:&nbsp;Real-Word of the Impella 2.5 Circulatory Support System in Complex High-Risk Percutaneous Coronary Intervention: The USpella Registry&nbsp;Reference:&nbsp;Brijeshwar maini, et al. Catheterization and Cardiovscular Intervention For about a decade angioplasty has begun to be performed in increasingly complex patients (PE) such as those with left coronary trunk injury, 3-vessel injury, poor ventricular function and surgically<a href="https://solaci.org/en/2012/11/29/complex-angioplasty-with-ventricular-assist/" title="Read more" >...</a>

Stent MGuard, primary angioplasty with a higher TIMI III

Original title:&nbsp;The MASTER Trial &#8211; Prospective, Randomized, Multicenter Evaluation of a Polyethylene Terephthalate Micronet Mesh&ndash;Covered Stent (MGuard) in ST-Segment Elevation Myocardial Infarction.&nbsp;Reference:&nbsp;Gregg W. Stone et. al. J Am Coll Cardiol 2012; 60: 1975-1984 Primary angioplasty has proven effective in restoring epicardial flow but myocardial perfusion is often suboptimal. One of the main mechanisms is distal<a href="https://solaci.org/en/2012/11/19/stent-mguard-primary-angioplasty-with-a-higher-timi-iii/" title="Read more" >...</a>

In patients with stroke history, Ticagrelor is superior to Clopidogrel

James SK, Storey RF, Khurmi N, et al. Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes and a History of Stroke or Transient Ischemic Attack. Circulation 2012. A sub-analysis of the PLATO study demonstrated similar superiority and the safety of ticagrelor in all patients, regardless of any previous history of stroke. Ticagrelor versus clopidogrel:<a href="https://solaci.org/en/2012/09/01/in-patients-with-stroke-history-ticagrelor-is-superior-to-clopidogrel/" title="Read more" >...</a>

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