Original Title: Meta-analysis of the long-term effect of routine aspiration thrombectomy in patients undergoing primary percutaneous coronary intervention. Reference: Mancini JG et al. Am J Cardiol. 2016; Epub ahead of print. A large meta-analyzis confirms routine aspiration thrombectomy in the context of primary PCI has no clinical benefit and could increase the risk of...
Stenting carotídeo sin stroke ¿Cómo lograr el patrón de oro en la seguridad? Dr. Robert Bersin (Estados Unidos)
Rutger-Jan Nuis 2014-10-30 MD, MSc, PhDDepartment of CardiologyThoraxcenter Rotterdam, Netherlands
There are many doubts about the benefit of manual thromboaspiration, not only in terms of improvement of the clinical end point but also the potential risk of stroke. The TOTAL (n = 10732) was a randomized study of routine manual thrombectomy versus angioplasty only in the context of ST segment elevation acute myocardial infarction and...
The aim of this study was to evaluate the effectiveness of supplementation with folic acid in primary prevention of stroke in hypertensive patients. Patients were randomized 1:1 to a fixed combination of enalapril 10 mg and folic acid 0.8 mg daily (n = 10,348) or only 10 mg enalapril (n = 10,354) followed at a...
Cardiac surgery with cardiopulmonary bypass results in an inflammatory response of the body that is usually associated with adverse outcome. The preventive use of corticosteroids attenuates this response although the benefit is not documented.7507 patients with a planned cardiac surgery were randomizedto methylprednisolone or placebo with the primary objective of assessing the mortality at 30...
It is shown that hypertension is associated with the occurrence of stroke but immediate treatment for an acute stroke itself is unclear. This study randomized 4071 acute stroke patients enrolled in an anti-hypertensive treatment (systolic pressure reduction by 10-25 % in the first 24 hours) versus control (stopping all antihypertensive drugs). The study included patients...
Fundamentals: Etiology of cryptogenic stroke stills a major challenge for medicine. Paradoxical embolism remains one of the possible causes. Undoubtedly, adults between 20 and 54 years represent a significant proportion of this population, and this is associated with a high morbidity and high costs not only in relation to the pathology itself but also to...
Background: The association between paradoxical embolism, including cryptogenic stroke, and the presence of patent foramen oval (PFO) has been found in previous clinical studies. However, the benefit of percutaneous PFO closure versus medical treatment is not clear, especially after the negative results of the randomized CLOSURE I trial. This study included patients with PFO and...
An hour before the presentation of the PREVAIL study, the ACC announced the cancellation of the release of the study results. Due to an error in the email system, results of the study were reported a few hours before his presentation. The ACC in an unprecedented decision cancelled the presentation of the study as well...