The transcatheter treatment of patent foramen ovale (PFO) has been shown to reduce thromboembolic events in patients with cryptogenic stroke. However, most of large randomized studies have failed to include patients with thrombophilia, either inherited or acquired. For instance, the RESPECT study excluded patients with antiphospholipid antibodies (AFA) or hyperhomocysteinemia, while the REDUCE screened for...
A new edition of the ProEducar Educational Bulletin has arrived for Fellows and interventionists in training. On this occasion, this bulletin addresses in depth the Percutaneous Closure of the Patent Foramen Ovale. Discover the ProEducar Educational Bulletin HERE (spanish version)
Cryptogenic stroke patients with migraine have high prevalence (79%) of patent foramen ovale (PFO) with right to left shunt. However, the timing of stroke in migraineurs is not usually associated to a migraine attack. These observations are consistent with the hypothesis that the most likely mechanism of stroke in these patients with migraine is a...
A new randomized controlled trial of patients who underwent patent foramen ovale (PFO) closure in cryptogenic stroke may provide certain morphological echocardiographic features that might allow us to better choose patients who would benefit more from PFO closure versus those for whom medical therapy would be more appropriate. Among patients with a recent cryptogenic stroke...
Migraine is one of the more frequent disabling disorders worldwide, but its physiopathology remains unclear. Since migraine is quite heterogeneous, individual therapies may not be effective for all patients. We still lack strategies to help us predict which patient subset might respond best to certain therapies. Read also: “Amplatzer and Figulla Devices Prove to Be...
Courtesy of Dr. José Álvarez. In patients with presumed paradoxical embolism through a patent foramen ovale (PFO) who are at high risk of recurrent thromboembolic events, percutaneous PFO closure is an alternative to pharmacological treatment. This closure has been shown to be safe and feasible with different devices including various technologies based on an umbrella,...
It is hypothesized that the presence of a right-left shunt can trigger migraine attacks. The aim of this study was to evaluate whether the closure of a patent foramen ovale may help treat patients with migraine with aura refractory to treatment. A total of 107 patients were included; 53 in the group of foramen ovale...
Ralph Stephan von Bardeleben2013-05-21
References: Matthew Nayor et al. Contemporary Approach to Paradoxical Embolism. Circulation. 2014;129:1892-1897. Marco Hernandez-Enrıquez et al. Current Indications for Percutaneous Closure of Patent Foramen Ovale. Rev Esp Cardiol. 2014;67(8):603–607. The debate on patent foramen ovale behavior in different clinical contexts remains open, no pun intended. Based on numerous observational studies and expert recommendations, when facing the...
Patent foramen ovale closure is the standard treatment for cryptogenic stroke patients. However, there are is little information on its long-term evolution. The aim of this study was to determine clinical outcomes (death, ischemic or bleeding events) after foramen ovale closure over a 10-year evolution. The study included 201 consecutive patients (mean age 47...