aortic stenosis

CLEAN-TAVI: transcatheter aortic valve replacement with cerebral protection

The stroke is a leading complication of post transcatheter aortic valve implantation increasing up to 3 times the mortality of these patients. In the works performed neuroimaging new post, TAVR defects were observed in two-thirds of patients and this increases the risk of post clinical stroke.&nbsp; There is a missing data in the literature of<a href="https://solaci.org/en/2015/06/24/clean-tavi-transcatheter-aortic-valve-replacement-with-cerebral-protection/" title="Read more" >...</a>

DISCOVER Trial: Results at one year of the new nonmetallic percutaneous aortic valve

Direct Flow Medical prosthesis is a nonmetallic, repositionable, recaptured valve (even after posts dilate), that does not require a pacemakers use during both implantation and post-dilatation.&nbsp; The aim of this study was to evaluate new valve results to one year in patients with symptomatic severe aortic stenosis with 19 and 26 mm ring, EuroScore of<a href="https://solaci.org/en/2015/06/24/discover-trial-results-at-one-year-of-the-new-nonmetallic-percutaneous-aortic-valve/" title="Read more" >...</a>

SALUS: New percutaneous valve with promising results regarding aortic regurgitation post implant.

Aortic regurgitation after valve implantation has been shown to be a long -term mortality predictor. The aim of this study was to test the new Direct Flow Medical system, which is more flexible prosthesis with a lower profile that could result in minor aortic regurgitation and less need for post expansion. This multicenter study included<a href="https://solaci.org/en/2015/06/24/salus-new-percutaneous-valve-with-promising-results-regarding-aortic-regurgitation-post-implant/" title="Read more" >...</a>

CoreValve superior to surgical aortic valve replacement in high-risk patients

The aim of this study was to compare percutaneous aortic valve replacement (TAVR) with the self-expanding Valve Core with conventional surgery in patients at high surgical risk. Patients with a valve area &lt; 0.8 cm2 , valvular index &le; 0.5 cm2 , a mean gradient of &nbsp;&gt; 40 mmHg or peak speeds above 4m /s<a href="https://solaci.org/en/2015/06/24/corevalve-superior-to-surgical-aortic-valve-replacement-in-high-risk-patients/" title="Read more" >...</a>

CHOICE Trial: Same mortality, less aortic regurgitation and need for a second prosthetic for Edwards Sapien XT valve versus Medtronic CoreValve

So far, there had been no published randomized studies comparing balloon-expandable Edwards&rsquo;s prosthesis and self-expandingCoreValve. The aim of this study was to compare the results between the two thin aortic prosthesis in high-risk surgical patients with severe symptomatic aortic stenosis undergoing valve replacement by percutaneous transfemoral access. This was a multicenter work (five centers in<a href="https://solaci.org/en/2015/06/24/choice-trial-same-mortality-less-aortic-regurgitation-and-need-for-a-second-prosthetic-for-edwards-sapien-xt-valve-versus-medtronic-corevalve/" title="Read more" >...</a>

GARY: German Aortic Valve Registry.

Presentation Summary: The German Aortic Stenosis Registry collected data from German centers. 13,860 patients who were undergoing valve replacement surgery or percutaneous valve implant in 2011 were included. As recommended in the European Cardiovascular Guidelines, this national registry suggests that percutaneous implant represents the dominant treatment of this disease, especially in high-risk patients. In high-risk<a href="https://solaci.org/en/2015/06/24/gary-german-aortic-valve-registry/" title="Read more" >...</a>

REPRISE II: LOTUS valve for percutaneous aortic valve replacement

The aim of this study was to evaluate the safety and efficacy of the new device in patients with severe aortic stenosis at high surgical risk. We included 120 patients with a mean age of 84 years and the aortic valve area of 0.7 cm2. The device was successfully implanted in all patients with a<a href="https://solaci.org/en/2015/06/24/reprise-ii-lotus-valve-for-percutaneous-aortic-valve-replacement/" title="Read more" >...</a>

Promising results of TAVR in Bicuspid Aortic

Original title:&nbsp;Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Disease.&nbsp;Reference:&nbsp;Darren Mylotte, et al. J Am Coll Cardiol 2014;64:2330-9 The bicuspid aortic valve (BAV) is present between 0.5% and 2% of the general population and up to 20% of patients older than 80 years who require aortic valve surgery. Literature on &nbsp; &nbsp; transcatheter aortic valve<a href="https://solaci.org/en/2015/01/08/promising-results-of-tavr-in-bicuspid-aortic/" title="Read more" >...</a>

Transcatheter Aortic Valve Replacement showed better results than conventional surgery in high risk diabetic patients.

Original title:&nbsp;Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes and Severe Aortic Stenosis at High Risk for Surgery An Analysis of the PARTNER Trial (Placement of Aortic Transcatheter Valve).&nbsp;Reference:&nbsp;Lindman BR et al. J Am Coll Cardiol. 2014 Mar 25;63(11):1090-9. Diabetes is associated to greater morbidity and mortality after surgical aortic valve replacement (SAVR),<a href="https://solaci.org/en/2014/03/26/transcatheter-aortic-valve-replacement-showed-better-results-than-conventional-surgery-in-high-risk-diabetic-patients/" title="Read more" >...</a>

Transcatheter Aortic Valve Replacement in patients with low ejection fraction: comparable outcomes with good ejection fraction patients.

Original title:&nbsp;Relation of Pre-procedural Assessment of Myocardial Contractility Reserve on Outcomes of Aortic Stenosis Patients with Impaired Left Ventricular Function Undergoing Transcatheter Aortic Valve Implantation&nbsp;Reference:&nbsp;Israel M. Barbash et al. Am J Cardiol. 2014, Epub ahead of print. &nbsp; Transcatheter aortic valve replacement (TAVI) is associated with a better left ventricular function (LV) in patients with<a href="https://solaci.org/en/2014/03/19/transcatheter-aortic-valve-replacement-in-patients-with-low-ejection-fraction-comparable-outcomes-with-good-ejection-fraction-patients/" title="Read more" >...</a>

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