After one-month dual antiplatelet therapy (DAPT) with aspirin and ticagrelor, a net clinical benefit was observed when de-escalating to clopidogrel in acute myocardial infarction (AMI) patients treated with PCI. We have discussed the pros and cons of de-escalating from a potent antiplatelets Such as ticagrelor to clopidogrel since the TOPIC presented at EuroPCR in 2017. What<a href="https://solaci.org/en/2021/05/18/acc-2021-talos-ami-de-escalating-from-ticagrelor-to-clopidogrel-after-one-month/" title="Read more" >...</a>
The most read scientific articles on interventional cardiology of april
01- Post MI Betablockers for Good? Patients receiving optimal medical treatment after MI do not seem to benefit from betablockers in the long term, provided they do not present cardiac failure or systolic function deterioration. Read more HERE 02- Thrombocytopenia and Thrombosis May Be Linked to AstraZeneca Vaccine, Analysis Reports This is one of the<a href="https://solaci.org/en/2021/05/07/the-most-read-scientific-articles-on-interventional-cardiology-of-april/" title="Read more" >...</a>
New Cardiac Failure Diagnoses after COVID-19 Infection
This is the largest study on new signs and symptoms of cardiac failure in patients after COVID-19. Even though low in prevalence, its occurrence in healthy patients with no prior risk factors is worrying. The potential for SARS-CoV 2 to directly affect the heart has been studied since the pandemic onset. These studies have shown<a href="https://solaci.org/en/2021/05/05/new-cardiac-failure-diagnoses-after-covid-19-infection/" title="Read more" >...</a>
Back to Basics: Ticagrelor Questioned and Clopidogrel in the Limelight
Yet another observational study has come to question the antiaggregation power of ticagrelor when it comes to death or MI reduction, pointing at its higher risk of bleeding vs. clopidogrel. This new analysis recently published in JAHA includes a large number of patients undergoing acute coronary syndrome (ACS) in the clinical practice. Ticagrelor has been<a href="https://solaci.org/en/2021/04/28/back-to-basics-ticagrelor-questioned-and-clopidogrel-in-the-limelight/" title="Read more" >...</a>
Cerebral Protection Devices during TAVR in the Daily Practice
The theory behind the use of cerebral protection devices during TAVR is good, but hard to test. The daily practice provides a far bigger number of patients, and therefore might be able to better show how to prevent one of the hardest events during TAVR. This study resorted to Germany’s TAVR database between 2015 and<a href="https://solaci.org/en/2021/04/21/cerebral-protection-devices-during-tavr-in-the-daily-practice/" title="Read more" >...</a>
Impact of FFR After Stenting: Useful or Mere Fun Fact?
Suboptimal fractional flow reserve (FFR) results after stenting only have a moderate impact on clinical hard points but might predict a much higher risk of reintervention. FFR has shown a huge impact on the decision-making process when it comes to revascularizing (or not) a lesion. Its impact after angioplasty has not been fully studied, particularly<a href="https://solaci.org/en/2021/04/12/impact-of-ffr-after-stenting-useful-or-mere-fun-fact/" title="Read more" >...</a>
Short Therapy and Monotherapy, Plenty of Evidence
A short dual antiplatelet therapy (DAPT) of 1 to 3 months followed by P2Y12 inhibitor monotherapy after second generation drug eluting stent (DES) implantation is safer and as effective as the traditional scheme. The idea is clear, but why hasn’t aspirin monotherapy been tested as follow up? Is aspirin old fashioned? Are there physiopathological reasons<a href="https://solaci.org/en/2021/04/12/short-therapy-and-monotherapy-plenty-of-evidence/" title="Read more" >...</a>
The Most Read Articles in Interventional Cardiology of March
01- Surgeons’ Claim on Low-Risk Patients with Aortic Stenosis Recent randomized trials including low-risk patients showed positive results for transcatheter aortic valve replacement (TAVR) compared with surgical aortic valve replacement. Read more HERE 02- Major Cause of Myocardial Injury by COVID-19 The most common cause of myocardial necrosis in patient undergoing COVID-19 infection is microthrombi. These<a href="https://solaci.org/en/2021/04/07/the-most-read-articles-in-interventional-cardiology-of-march/" title="Read more" >...</a>
Biodegradable Polymer Myth Also Debunked for ACSs
During TCT 2020 a preview of the results of the comparison of drug-eluting stents (DES) with biodegradable-polymer vs. durable-polymer in patients with acute coronary syndrome (ACS) was presented. The fine print and the final paper for HOST-REDUCE-POLYTECH-ACS are now published, and they lower the expectations set on biodegradable polymers. In patients with ACS undergoing angioplasty, biodegradable-polymer<a href="https://solaci.org/en/2021/04/05/biodegradable-polymer-myth-also-debunked-for-acss/" title="Read more" >...</a>
Five-Years After PFO Closure: Procedural Safety and Effectiveness
Five-year outcomes of the randomized REDUCE study showed a continuous benefit from patent foramen ovale (PFO) closure compared with antiplatelet agents to prevent cryptogenic strokes. The most important aspect of this result seems to be the idea that PFO closure in selected patients offers durable benefit with guaranteed long-term safety. The original results from REDUCE<a href="https://solaci.org/en/2021/03/22/five-years-after-pfo-closure-procedural-safety-and-effectiveness/" title="Read more" >...</a>